Issue

Vol. 35 No. 3 (2023): Vol 35 Issue 3, 2023

Copyright (c) 2023 AJC

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Green Synthesis of Gold Nanoparticles using Carambola Fruit Extract and Evaluation of their Antioxidant and Anticancer Efficiency

https://doi.org/10.14233/ajchem.2023.26988
Alampally Bangaru Babu
Department of Chemistry, Osmania University, Hyderabad-500007, India ; Department of Chemistry, Government Degree College, Puttur-517583, India
Kanaka Durga Bhavani Anagani
Department of Chemistry, Osmania University, Hyderabad-500007, India
Pidamarthi Sravanthi
Department of Chemistry, T.T.W.R. Degree College (M), Maripeda-506315, India

Corresponding Author(s) : Kanaka Durga Bhavani Anagani

durgabhavani237@gmail.com

Asian Journal of Chemistry, Vol. 35 No. 3 (2023): Vol 35 Issue 3, 2023

Abstract

In this study, a successful synthesis of gold nanoparticles (AuNPs) using extract from the Carambola fruit was carried out. Remarkably fast reduction of Au3+ ions was observed when aqueous chloroauric acid was treated with star fruit powder at 60 ºC and this was obtained without the use of any stabilizing or reducing agents. The UV-visible, FT-IR, DLS, XRD, SEM and TEM were used to study the synthesized AuNPs. The FT-IR studies suggested that the phenolic group may have contributed to the reduction of Au3+. The DLS particle size analysis and TEM measurements revealed that AuNPs had a mean particle size of 10 nm and were nearly spherical in form. The crystalline character of AuNPs was established by TEM-SAED image and XRD analyses. Zeta potential measurements were used to analyze the stability of AuNPs. The synthesized AuNPs effectively scavenge free radicals such as DPPH, NO• and H2O2 with % inhibition values of 57.12, 58.75 and 60.23, respectively. The MTT assay of the anticancer activity demonstrated that the synthesized AuNPs worked effectively against MCF7 cell lines and are comparable to those of standard cancer drugs.

Keywords

Gold nanoparticles Carambola fruit extract Antioxidant ativity Anticancer activity
Bangaru Babu, A., Durga Bhavani Anagani, K., & Sravanthi, P. (2023). Green Synthesis of Gold Nanoparticles using Carambola Fruit Extract and Evaluation of their Antioxidant and Anticancer Efficiency. Asian Journal of Chemistry, 35(3), 739–747. https://doi.org/10.14233/ajchem.2023.26988
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. M.P. Patil, M. Kang, I. Niyonizigiye, A. Singh, J.-O. Kim, Y.B. Seo and G.-D. Kim, Colloids Surf. B Biointerfaces, 183, 110455 (2019); https://doi.org/10.1016/j.colsurfb.2019.110455
  2. C. Barai, K. Paul, A. Dey, S. Manna, S. Roy, C. Mukhopadhyay and B.G. Bag, Nano Converg., 5, 10 (2018); https://doi.org/10.1186/s40580-018-0142-5
  3. S. Miditana, S.R. Tirukkovalluri and I.M. Raju, Nano Systems: Phys. Chem. Maths, 13, 104 (2022); https://doi.org/10.17586/2220-8054-2022-13-1-104-114
  4. O.M. El-Borady, M.S. Ayat, M.A. Shabrawy and P. Millet, Adv. Powder Technol., 31, 4390 (2020); https://doi.org/10.1016/j.apt.2020.09.017
  5. E. Darabpour, N. Kashef, S.M. Amini, S. Kharrazi and G.E. Djavid, J. Drug Deliv. Sci. Technol., 37, 134 (2017); https://doi.org/10.1016/j.jddst.2016.12.007
  6. A.I. El-Batel, A.A.M. Ashem and N.M. Abdelbaky, Sringerplus, 2, 129 (2013); https://doi.org/10.1186/2193-1801-2-129
  7. M.S. Kang, S.Y. Lee, K.S. Kim and D.-W. Han, Pharmaceutics, 12, 701 (2020); https://doi.org/10.3390/pharmaceutics12080701
  8. K.K. Bharadwaj, B. Rabha, S. Pati, T. Sarkar, B.K. Choudhury, A. Barman, D. Bhattacharjya, A. Srivastava, D.
  9. aishya, H.A. Edinur, Z. Abdul Kari and N.H. Mohd Noor, Molecules, 26, 6389 (2021); https://doi.org/10.3390/molecules26216389
  10. M. Hassanisaadi, G.H. Bonjar, A. Rahdar, S. Pandey, A. Hosseinipour and R. Abdolshahi, Nanomaterials, 11, 2033 (2021); https://doi.org/10.3390/nano11082033
  11. K. Perveen, F.M. Husain, F.A. Qais, A. Khan, S. Razak, T. Afsar, P. Alam, A.M. Almajwal and M.M.A. Abulmeaty, Biomolecules, 11, 197 (2021); https://doi.org/10.3390/biom11020197
  12. B. Rabha, K.K. Bharadwaj, N. Boro, A. Ghosh, S.K. Gogoi, R.S. Varma and D. Baishya, Green Chem., 23, 7701 (2021); https://doi.org/10.1039/D1GC02260A
  13. D.A. Lomelí-Rosales, A. Zamudio-Ojeda, O.K. Reyes-Maldonado, M.E. López-Reyes, G.C. Basulto-Padilla, E.J. Lopez-Naranjo, V.M. Zuñiga-Mayo and G. Velázquez-Juárez, Molecules, 27, 1692 (2022); https://doi.org/10.3390/molecules27051692
  14. G. Suriyakala, S. Sathiyaraj, R. Babujanarthanam, K.M. Alarjani, D.S. Hussein, R.A. Rasheed and K. Kanimozhi, J. King Saud Univ. Sci., 34, 101830 (2022); https://doi.org/10.1016/j.jksus.2022.101830
  15. N. Muniyappan, M. Pandeeswaran and A. Amalraj, Environ. Chem. Ecotoxicol., 3, 117 (2021); https://doi.org/10.1016/j.enceco.2021.01.002
  16. S. Veena, T. Devasena, S.S.M. Sathak, M. Yasasve and L.A. Vishal, J. Cluster Sci., 30, 1591 (2019); https://doi.org/10.1007/s10876-019-01601-z
  17. H. Shabestarian, M. Homayouni-Tabrizi, M. Soltani, F. Namvar, S. Azizi, R. Mohamad and H. Shabestarian, Mater. Res., 20, 264 (2017); https://doi.org/10.1590/1980-5373-mr-2015-0694
  18. B. Kumar, K. Smita, K.S. Vizuete and L. Cumbal, Biol. Med., 8, 290 (2016); https://doi.org/10.4172/0974-8369.1000290
  19. J.K. Patra, Y. Kwon and K.-H. Baek, Adv. Powder Technol., 27, 2204 (2016).
  20. J.K. Patra and K.-H. Baek, Int. J. Nanomedicine, 10, 7253 (2015); https://doi.org/10.2147/IJN.S95483
  21. R. Vijayan, S. Joseph and B. Mathew, Bioprocess Biosyst. Eng., 42, 305 (2019); https://doi.org/10.1007/s00449-018-2035-8
  22. E. Mzwd, N.M. Ahmed, N. Suradi, S.K. Alsaee, A.S. Altowyan, M.A. Almessiere and A.F. Omar, Sci. Rep., 12, 10549 (2022); https://doi.org/10.1038/s41598-022-14339-y
  23. P. Kumari and A. Meena, Colloids Surf. A Physicochem. Eng. Asp., 606, 125447 (2020); https://doi.org/10.1016/j.colsurfa.2020.125447
  24. S. Suresh, S. Vennila, J.A. Lett, I. Fatimah, F. Mohammad, H.A. AlLohedan, S.F. Alshahateet, M.A.M. Hossain and M.R. Johan, Inorg. Nano-Met. Chem., 52, 173 (2022); https://doi.org/10.1080/24701556.2021.1880437
  25. N. Muthu, S.Y. Lee, K.K. Phua and S.J. Bhore, Bioinformation, 12, 420 (2016); https://doi.org/10.6026/97320630012420
  26. X.-J. Duan, W.-W. Zhang, X.-M. Li and B.-G. Wang, Food Chem., 95, 37 (2006); https://doi.org/10.1016/j.foodchem.2004.12.015
  27. L. Marcocci, L. Packer, M.T. Droy-Lefaix, A. Sekaki and M. GardesAlbert, Methods Enzymol., 234, 462 (1994); https://doi.org/10.1016/0076-6879(94)34117-6
  28. Y. Çetinkaya, H. Göçer, A. Menzek and I. Gülçin, Arch. Pharm., 345, 323 (2012); https://doi.org/10.1002/ardp.201100272
  29. A. Venkanna, B. Siva, B. Poornima, P.R. Rao Vadaparthi, K.R. Prasad, K.A. Reddy, G.B.P. Reddy and K.S. Babu, Fitoterapia, 95, 102 (2014); https://doi.org/10.1016/j.fitote.2014.03.003
  30. S.J. Nadaf, N.R. Jadhav, H.S. Naikwadi, P.L. Savekar, I.D. Sapkal, M.M. Kambli and I.A. Desai, OpenNano, 8, 100076 (2022); https://doi.org/10.1016/j.onano.2022.100076
Read More
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 3 Download : 0