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Vol. 35 No. 12 (2023): Vol 35 Issue 12, 2023

Copyright (c) 2023 Santosh Pore

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Natural Surfactant Mediated Synthesis of 4-Aryl Substituted 3,4-Dihydropyrimidinones

https://doi.org/10.14233/ajchem.2023.30684
Santosh B. Pore
Department of Chemistry, Prof. (Dr.) N.D. Patil Mahavidyalaya, Malkapur-415101, India
https://orcid.org/0000-0002-7777-2581

Corresponding Author(s) : Santosh B. Pore

santoshbpore@gmail.com

Asian Journal of Chemistry, Vol. 35 No. 12 (2023): Vol 35 Issue 12, 2023

Abstract

Present work describes the synthesis of 4-aryl substituted 3,4-dihydropyrimidinones (DHPMs) using aqueous extract of pericarp of Sapindus trifoliatus fruit as a green catalyst. The reaction is a one-pot reaction, similar to classical Biginelli reaction employing an aromatic aldehyde, urea and active methylene compound (ethyl acetoacetate) as substrates. Desired DHPMs were yielded within 2 h at room temperature. The key advantage of the present strategy was its low dependence on organic solvents as green synthesis.

Keywords

Substituted 3,4-Dihydropyrimidinones Sapindus trifoliatus Biginelli reaction
Pore, S. B. (2023). Natural Surfactant Mediated Synthesis of 4-Aryl Substituted 3,4-Dihydropyrimidinones. Asian Journal of Chemistry, 35(12), 3037–3041. https://doi.org/10.14233/ajchem.2023.30684
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