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Vol. 35 No. 11 (2023): Vol 35 Issue 11, 2023

Copyright (c) 2023 Abhijit Biswas Abhijit Biswas

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Graphene Oxide-based Gel as Potential Nanomaterial for Sustained Release of an Anticancer Drug

https://doi.org/10.14233/ajchem.2023.30266
Abhijit Biswas
Department of Chemistry, Krishnagar Government College, Krishnagar-741101, India
https://orcid.org/0000-0003-2314-7796

Corresponding Author(s) : Abhijit Biswas

biswas.abhijit5@gmail.com

Asian Journal of Chemistry, Vol. 35 No. 11 (2023): Vol 35 Issue 11, 2023

Abstract

A new graphene oxide-based gel comprised of mitoxantrone an anticancer drug and graphene oxide has been synthesized in water at room temperature. This gel-based soft material was formed due to the supramolecular interactions including hydrogen bonding, acid– base and p–p stacking. Transmission electron microscopy, atomic force microscopy, X-ray diffraction and rheological studies have been employed to characterize the gel. By introducing a small quantity of Ca2+ ions at room temperature, this hybrid gel can effectively facilitate the sustained and controlled release of mitoxantrone drug. The release of the drug molecules was checked and discussed using UV-visible spectroscopic analyses. With the advantages of this graphene oxide-based gel, the soft gel-based material could be a soft drug-releasing agent.

Keywords

Graphene Oxide Gel Controlled release. Anticancer drug Mitoxantrone
Biswas, A. (2023). Graphene Oxide-based Gel as Potential Nanomaterial for Sustained Release of an Anticancer Drug. Asian Journal of Chemistry, 35(11), 2733–2738. https://doi.org/10.14233/ajchem.2023.30266
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