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Vol. 38 No. 7 (2026): Vol. 38, No 7 (2026)

Copyright (c) 2026 SUNANDAN BARUAH, Nairika Deka, Ria Ghosh, Lopamudra Roy, ASIM KUMAR MALLICK, SAMIR KUMAR PAL

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Encapsulation of Chitosan Functionalised Zinc Oxide Nanoparticles in Nylon Nanofibre Matrix for Water-Resistant Antibacterial Coating

https://doi.org/10.14233/ajchem.2026.35861
Nairika Deka
Centre of Excellence Nanotechnology, Assam down town University, Gandhi Nagar, Panikhaiti, Guwahati-781026, India
https://orcid.org/0009-0009-7337-2925
Ria Ghosh
Department of Chemical and Biological Sciences, S.N. Bose National Centre for Basic Sciences, Block JD, Sector 3, Salt Lake, Kolkata-700106, India
https://orcid.org/0000-0002-5817-1852
Lopamudra Roy
Department of Applied Optics and Photonics, JD-2, Sector-III, Salt Lake, Kolkata-700106, India
Asim Kumar Mallick
Department of Pediatric Medicine, Nil Ratan Sirkar Medical College and Hospital, 38, Acharya Jagadish Chandra Bose Rd, Sealdah, Raja Bazar, Kolkata-700014, India
Samir Kumar Pal
Department of Chemical and Biological Sciences, S.N. Bose National Centre for Basic Sciences, Block JD, Sector 3, Salt Lake, Kolkata-700106, India
https://orcid.org/0000-0001-6943-5828
Sunandan Baruah
Department of Electronics & Communication, Assam Skill University, Bidya Nagar, Gerimari, Mangaldai-784125, India
https://orcid.org/0000-0003-2963-6128

Corresponding Author(s) : Sunandan Baruah

s.baruah@asu.ac.in

Asian Journal of Chemistry, Vol. 38 No. 7 (2026): Vol. 38, No 7 (2026)

Abstract

Entrapment of antibacterial agents in a hydrophobic self-supported environment is a challenge for their accessibility to the external environment to reach the bacterial infection. A self-supporting nylon nanofibre matrix (NNFM) embedded with chitosan-functionalised zinc oxide nanoparticles (CTS-ZnO NPs, ~50 nm) was developed as a photoactive antimicrobial nanohybrid. FTIR confirmed the successful functionalisation of ZnO NPs with chitosan, while XRD verified their crystalline wurtzite structure. DLS analysis demonstrated good colloidal stability and electron microscopy revealed the morphology and uniform distribution of the nanoparticles within the NNFM. Picosecond-resolved UV–Vis spectroscopy showed rapid transfer of photogenerated electrons from CTS-ZnO NPs to the NNFM, followed by their migration into the aqueous medium, where they generated reactive oxygen species (ROS). The combined effects of ROS production, ZnO and chitosan led to significant disruption of bacterial biofilms. The water-resistant nature of the nylon matrix further highlights the potential of this nanohybrid for smart wound dressings aimed at treating biofilm-associated bacterial infections.

Keywords

Zinc oxide Antibacterial Biofilm Nanofiber Staphylococcus aureus
(1)
Deka, N.; Ghosh, R.; Roy, L.; Mallick, A. K.; Pal, S. K.; Baruah, S. Encapsulation of Chitosan Functionalised Zinc Oxide Nanoparticles in Nylon Nanofibre Matrix for Water-Resistant Antibacterial Coating. ajc 2026, 38, 1912-1920.
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