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Vol. 38 No. 2 (2026): Vol 38 Issue 2, 2026

Copyright (c) 2026 Monica. S, Kavitha rani. P.R, Thamarai Chelvi. c, Hari Prasad. S

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Green Synthesis of ZnO Nanoparticles Mediated by Eleutherine bulbosa: Multifunctional Properties for Biomedical and Environmental Applications

https://doi.org/10.14233/ajchem.2026.35023
S. Monica
P.G. and Research Department of Chemistry, The Standard Fireworks Rajaratnam College for Women (Affiliated to Madurai Kamaraj University), Sivakasi-626123, India
https://orcid.org/0009-0009-9741-2485
P.R. Kavitha Rani
P.G. and Research Department of Chemistry, The Standard Fireworks Rajaratnam College for Women (Affiliated to Madurai Kamaraj University), Sivakasi-626123, India
https://orcid.org/0000-0001-6788-6465
C. Thamarai Chelvi
P.G. and Research Department of Chemistry, The Standard Fireworks Rajaratnam College for Women (Affiliated to Madurai Kamaraj University), Sivakasi-626123, India
https://orcid.org/0000-0001-6948-3416
S. Hari Prasad
P.G. and Research Department of Chemistry, University College (Affiliated to Kerala University), Thiruvananthapuram-695034, India
https://orcid.org/0000-0002-3006-3614

Corresponding Author(s) : P.R. Kavitha Rani

raghavkavitha@gmail.com

Asian Journal of Chemistry, Vol. 38 No. 2 (2026): Vol 38 Issue 2, 2026

Abstract

In this work, zinc oxide nanoparticles (ZnO NPs) were prepared using an eco-friendly aqueous extract of Eleutherine bulbosa bulbs and were characterised by spectral and morphological techniques. The XRD confirmed sharp peaks with a crystallite size of 27.21 nm. Morphological studies showed flake-like structures in SEM and predominantly spherical particles in HR-TEM. TGA demonstrated good thermal stability with a weight loss from 96% to 65%. Functionally, the ZnO NPs exhibited strong antioxidant activity (IC50 = 44.15 µg/mL) and potent anticancer effects against human breast cancer cells (IC50 = 21.12 µg/mL). Photocatalytic activity was also significant, achieving 80% methylene blue degradation under UV light within 100 min.

Keywords

Green synthesis E. bulbosa Antioxidant activity Anticancer activity Photocatalysis
(1)
Monica, S.; Rani, P. K.; Chelvi, C. T.; Prasad, S. H. Green Synthesis of ZnO Nanoparticles Mediated by Eleutherine Bulbosa: Multifunctional Properties for Biomedical and Environmental Applications. ajc 2026, 38, 434-442.
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References
  1. V. Aliko, L. Vasjari, E.S. Istifli, G. Gjonaj, F. Impellitteri, C. Faggio, E. Benedetti, S. Zugaro, A. Iannetta and M. Perugini, Aquat. Toxicol., 276, 107112 (2024); https://doi.org/10.1016/j.aquatox.2024.107112 DOI: https://doi.org/10.1016/j.aquatox.2024.107112
  2. M. Alam, Nanotechnol. Rev., 10, 1079 (2021); https://doi.org/10.1515/ntrev-2021-0069 DOI: https://doi.org/10.1515/ntrev-2021-0069
  3. K.V. Dhandapani, D. Anbumani, A.D. Gandhi, P. Annamalai, B.S. Muthuvenkatachalam, P. Kavitha and B. Ranganathan, Biocatal. Agric. Biotechnol., 24, 101517 (2020); https://doi.org/10.1016/j.bcab.2020.101517 DOI: https://doi.org/10.1016/j.bcab.2020.101517
  4. R. Singh, C. Hano, G. Nath and B. Sharma, Biomolecules, 11, 299 (2021); https://doi.org/10.3390/biom11020299 DOI: https://doi.org/10.3390/biom11020299
  5. S. Wu, S. Rajeshkumar, M. Madasamy and V. Mahendran, Artif. Cells Nanomed. Biotechnol., 48, 1153 (2020); https://doi.org/10.1080/21691401.2020.1817053 DOI: https://doi.org/10.1080/21691401.2020.1817053
  6. C.G. Joshi, A. Danagoudar, J. Poyya, A.K. Kudva and B.L. Dhananjaya, Process Biochem., 63, 137 (2017); https://doi.org/10.1016/j.procbio.2017.09.008 DOI: https://doi.org/10.1016/j.procbio.2017.09.008
  7. A. Rana, S. Pathak, D.K. Lim, S.K. Kim, R. Srivastava, S.N. Sharma and R. Verma, ACS Appl. Nano Mater., 6, 8106 (2023); https://doi.org/10.1021/acsanm.3c01351 DOI: https://doi.org/10.1021/acsanm.3c01351
  8. I. Ahmed, F.A. Mir and J.A. Banday, BioNanoSci., 13, 1541 (2023); https://doi.org/10.1007/s12668-023-01194-y DOI: https://doi.org/10.1007/s12668-023-01194-y
  9. L. Devi, P. Kushwaha, T.M. Ansari, A. Kumar and A. Rao, Biol. Trace Elem. Res., 202, 3383 (2024); https://doi.org/10.1007/s12011-023-03920-9 DOI: https://doi.org/10.1007/s12011-023-03920-9
  10. K. Fatima, M. Asif, U. Farooq, S.J. Gilani, M.N. Bin Jumah and M.M. Ahmed, ACS Omega, 9, 15882 (2024); https://doi.org/10.1021/acsomega.3c08143 DOI: https://doi.org/10.1021/acsomega.3c08143
  11. S. Sabir, M. Arshad and S.K. Chaudhari, Scient. World J., 2014, 925494 (2014); https://doi.org/10.1155/2014/925494 DOI: https://doi.org/10.1155/2014/925494
  12. M.A. Alghuthaymi, H. Almoammar, M. Rai, E. Said-Galiev and K.A. Abd-Elsalam, Biotechnol. Biotechnol. Equip., 29, 221 (2015); https://doi.org/10.1080/13102818.2015.1008194 DOI: https://doi.org/10.1080/13102818.2015.1008194
  13. C.A. Fernandes, N. Jesudoss M, A. Nizam, S.B.N. Krishna and V.V. Lakshmaiah, ACS Omega, 8, 39315 (2023); https://doi.org/10.1021/acsomega.3c04857 DOI: https://doi.org/10.1021/acsomega.3c04857
  14. S. Maher, B. Zamina, M. Riaz, S. Riaz, N. Khalid, M. Imran, S. Fahmid, H. Ishtiaq and S. Parveen, ACS Omega, 8, 46715 (2023); https://doi.org/10.1021/acsomega.3c05947 DOI: https://doi.org/10.1021/acsomega.3c05947
  15. Y. Sun, W. Zhang, Q. Li, H. Liu and X. Wang, Adv. Sens. Energy Mater., 2, 100069 (2023); https://doi.org/10.1016/j.asems.2023.100069 DOI: https://doi.org/10.1016/j.asems.2023.100069
  16. A.A. Kamarudin, N.H. Sayuti, N. Saad, N.A.A. Razak and N.M. Esa, Int. J. Mol. Sci., 22, 6747 (2021); https://doi.org/10.3390/ijms22136747 DOI: https://doi.org/10.3390/ijms22136747
  17. R.M.G. da Silva, C.P. Alves, F.C. Barbosa, H.H. Santos, K.M. Adão, F.O. Granero, C.C.M. Figueiredo, N. Nicolau Jr. and L.P. Silva, J. Ethnopharmacol., 318, 117005 (2024); https://doi.org/10.1016/j.jep.2023.117005 DOI: https://doi.org/10.1016/j.jep.2023.117005
  18. N. Panyachariwat, A. Jimtaisong and N. Saewan, Cosmetics, 11, 111 (2024); https://doi.org/10.3390/cosmetics11040111 DOI: https://doi.org/10.3390/cosmetics11040111
  19. L. Motelica, B.S. Vasile, A. Ficai, A.V. Surdu, D. Ficai, O.C. Oprea, E. Andronescu, G. Mustatea, E.L. Ungureanu and A.A. Dobre, Pharmaceutics, 15, 2470 (2023); https://doi.org/10.3390/pharmaceutics15102470 DOI: https://doi.org/10.3390/pharmaceutics15102470
  20. A. Anjum, M. Hashim, S.A. Malik, M. Khan, J.M. Lorenzo, B.H. Abbasi and C. Hano, Cancers, 13, 4570 (2021); https://doi.org/10.3390/cancers13184570 DOI: https://doi.org/10.3390/cancers13184570
  21. S. Jha, R. Rani and S. Singh, J. Inorg. Organomet. Polym., 33, 1437 (2023); https://doi.org/10.1007/s10904-023-02550-x DOI: https://doi.org/10.1007/s10904-023-02550-x
  22. M.A. Saifi, A. Negi, A. Kaur, Lakshya, R. Merugu, S. Negi and M.T. Yassin, Inorg. Chem. Commun., 186, 116214 (2026); https://doi.org/10.1016/j.inoche.2026.116214 DOI: https://doi.org/10.1016/j.inoche.2026.116214
  23. L.A. Pham-Huy, H. He and C. Pham-Huyc, Int. J. Biomed. Sci., 4, 89 (2008); https://doi.org/10.59566/IJBS.2008.4089 DOI: https://doi.org/10.59566/IJBS.2008.4089
  24. G. Pizzino, N. Irrera, M. Cucinotta, G. Pallio, F. Mannino, V. Arcoraci, F. Squadrito, D. Altavilla and A. Bitto, Oxid. Med. Cell. Longev., 2017, 8416763 (2017); https://doi.org/10.1155/2017/8416763 DOI: https://doi.org/10.1155/2017/8416763
  25. V.S. Rani, World J. Pharm. Res., 7, 1022 (2018).
  26. T. Safawo, B.V. Sandeep, S. Pola and A. Tadesse, OpenNano, 3, 56 (2018); https://doi.org/10.1016/j.onano.2018.08.001 DOI: https://doi.org/10.1016/j.onano.2018.08.001
  27. L. Florento, R. Matias, E. Tuano, K. Santiago, F. Cruz and A. Tuazon, Int. J. Biomed. Sci., 8, 76 (2012); https://doi.org/10.59566/IJBS.2012.8076 DOI: https://doi.org/10.59566/IJBS.2012.8076
  28. P. Jamdagni, P. Khatri and J.S. Rana, J. King Saud Univ. Sci., 30, 168 (2018); https://doi.org/10.1016/j.jksus.2016.10.002 DOI: https://doi.org/10.1016/j.jksus.2016.10.002
  29. G. Sangeetha, S. Rajeshwari and R. Venckatesh, Mater. Res. Bull., 46, 2560 (2011); https://doi.org/10.1016/j.materresbull.2011.07.046 DOI: https://doi.org/10.1016/j.materresbull.2011.07.046
  30. S.J. Jun, S. Kim and J.H. Han, J. Kor. Ceram. Soc., 35, 209 (1998).
  31. M. Ramesh, M. Anbuvannan and G. Viruthagiri, Spectrochim. Acta A Mol. Biomol. Spectrosc., 136, 864 (2015); https://doi.org/10.1016/j.saa.2014.09.105 DOI: https://doi.org/10.1016/j.saa.2014.09.105
  32. S.K. Das, A.R. Das and A.K. Guha, Langmuir, 25, 8192 (2009); https://doi.org/10.1021/la900585p DOI: https://doi.org/10.1021/la900585p
  33. N.M. Nurazzi, M.R.M. Asyraf, M. Rayung, M.N.F. Norrrahim, S.S. Shazleen, M.S.A. Rani, A.R. Shafi, H.A. Aisyah, M.H.M. Radzi, F.A. Sabaruddin, R.A. Ilyas, E.S. Zainudin and K. Abdan, Polymers, 13, 2710 (2021); https://doi.org/10.3390/polym13162710 DOI: https://doi.org/10.3390/polym13162710
  34. B. Naiel, M. Fawzy, A.E.D. Mahmoud and M.W.A. Halmy, Sci. Rep., 14, 13459 (2024); https://doi.org/10.1038/s41598-024-63459-0 DOI: https://doi.org/10.1038/s41598-024-63459-0
  35. K. Sarwar, Z.-H. Nazli, H. Munir, M. Aslam and A. Khalofah, Sci. Rep., 15, 20413 (2025); https://doi.org/10.1038/s41598-025-08839-w DOI: https://doi.org/10.1038/s41598-025-08839-w
  36. M. Manikanika and L. Chopra, Mater. Today Proc., 72, 1613 (2023); https://doi.org/10.1016/j.matpr.2022.09.413 DOI: https://doi.org/10.1016/j.matpr.2022.09.413
  37. N.O. Sanjeev, A.E. Valsan, S. Zachariah and S.T. Vasu, J. Hazard. Toxic Radioact. Waste, 27, 04023027 (2023); https://doi.org/10.1061/JHTRBP.HZENG-1217 DOI: https://doi.org/10.1061/JHTRBP.HZENG-1217
  38. M. Naseer, U. Aslam, B. Khalid and B. Chen, Sci. Rep., 10, 9055 (2020); https://doi.org/10.1038/s41598-020-65949-3 DOI: https://doi.org/10.1038/s41598-020-65949-3
  39. S.S. Naser, B. Ghosh, F.Z. Simnani, D. Singh, A. Choudhury, A. Nandi, A. Sinha, E. Jha, P.K. Panda, M. Suar and S.K. Verma, J. Nanotheranostics, 4, 248 (2023); https://doi.org/10.3390/jnt4030012 DOI: https://doi.org/10.3390/jnt4030012
  40. J. Gupta, J. Mohapatra and D. Bahadur, Dalton Trans., 46, 685 (2017); https://doi.org/10.1039/C6DT03713E DOI: https://doi.org/10.1039/C6DT03713E
  41. B. Naiel, M. Fawzy, M.W.A. Halmy and A.E.D. Mahmoud, Sci. Rep., 12, 20370 (2022); https://doi.org/10.1038/s41598-022-24805-2 DOI: https://doi.org/10.1038/s41598-022-24805-2
  42. A. Narayana, S.A. Bhat, A. Fathima, S.V. Lokesh, S.G. Surya and C.V. Yelamaggad, RSC Adv., 10, 13532 (2020); https://doi.org/10.1039/D0RA00478B DOI: https://doi.org/10.1039/D0RA00478B
  43. D. Mutukwa, R. Taziwa and L.E. Khotseng, Nanomaterials, 12, 3456 (2022); https://doi.org/10.3390/nano12193456 DOI: https://doi.org/10.3390/nano12193456
  44. A.I. Osman, Y. Zhang, M. Farghali, A.K. Rashwan, A.S. Eltaweil, E.M. Abd El-Monaem, I.M.A. Mohamed, M.M. Badr, I. Ihara, D.W. Rooney and P.-S. Yap, Environ. Chem. Lett., 22, 841 (2024); https://doi.org/10.1007/s10311-023-01682-3 DOI: https://doi.org/10.1007/s10311-023-01682-3
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