Copyright (c) 2022 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
LC-MS/MS Analysis of Glyphosate, Aminomethylphosphonic acid and Glufosinate in Honey
Corresponding Author(s) : A.V. Sorokin
Asian Journal of Chemistry,
Vol. 34 No. 8 (2022): Vol 34 Issue 8, 2022
Abstract
A confirmatory method was developed and validated for determination of glyphosate (Gly), glufosinate (Glu) and aminomethylphosphonic acid (AMPA) in honey using reversed-phase high performance liquid chromatography (RP-HPLC) coupled with tandem mass-spectrometry (MS/MS). The sample preparation approach consists of extraction by acidified solutions followed by SPE on Oasis HLB, derivatization by FMOC-Cl, concentration and another SPE stage on Oasis WCX. The limit of quantification (LOQ) of 0.05 ppm was reached for Gly, AMPA and Glu. All accuracy values ranged from 85% to 110% for all analytes using both primary and secondary quantitative ion transitions (RSD ≤ 10%). Correlation coefficients were higher than 0.99. The method was applied in 2018-19 for monitoring of honey samples, which revealed agricultural territories with intensive use of glyphosate.
Keywords
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX
- S. Singh, V. Kumar, S. Datta, A.B. Wani, D.S. Dhanjal, R. Romero and J. Singh, Environ. Chem. Lett., 18, 663 (2020); https://doi.org/10.1007/s10311-020-00969-z
- C.M. Benbrook, Environ. Sci. Eur., 28, 3 (2016); https://doi.org/10.1186/s12302-016-0070-0
- http://www.weedscience.org/ (Accessed on 22.01.2022).
- M.C. Arregui, A. Lenardón, D. Sanchez, M.I. Maitre, R. Scotta and S. Enrique, Pest Manag. Sci., 60, 163 (2004); https://doi.org/10.1002/ps.775
- S.H. Bai and S.M. Ogbourne, Environ. Sci. Pollut. Res. Int., 23, 18988 (2016); https://doi.org/10.1007/s11356-016-7425-3
- T. Shushkova, I. Ermakova and A. Leontievsky, Biodegradation, 21, 403 (2010); https://doi.org/10.1007/s10532-009-9310-y
- M. Pérez Rodríguez, C. Melo, E. Jiménez and J. Dussán, Agriculture, 9, 217 (2019); https://doi.org/10.3390/agriculture9100217
- L. Simonsen, I.S. Fomsgaard, B. Svensmark and N.H. Spliid, J. Environ. Sci. Health B, 43, 365 (2008); https://doi.org/10.1080/03601230802062000
- W.M. Farina, M.S. Balbuena, L.T. Herbert, C. Mengoni Goñalons and D.E. Vázquez, Insects, 10, 354 (2019); https://doi.org/10.3390/insects10100354
- R.M. Mann and J.R. Bidwell, Arch. Environ. Contam. Toxicol., 36, 193 (1999); https://doi.org/10.1007/s002449900460
- V. Langiano and C.B.R. Martinez, Comp. Biochem. Physiol. C Toxicol. Pharmacol., 147, 222 (2008); https://doi.org/10.1016/j.cbpc.2007.09.009
- N.K. Neskovic, V. Poleksi, I. Elezovi, V. Karan and M. Budimir, Bull. Environ. Contam. Toxicol., 56, 295 (1996); https://doi.org/10.1007/s001289900044
- S. Richard, S. Moslemi, H. Sipahutar, N. Benachour and G.-E. Seralini, Environ. Health Perspect., 113, 716 (2005); https://doi.org/10.1289/ehp.7728
- V.J. Koller, M. Fürhacker, A. Nersesyan, M. Mišík, M. Eisenbauer and S. Knasmueller, Arch. Toxicol., 86, 805 (2012); https://doi.org/10.1007/s00204-012-0804-8
- N. Chamkasem, C. Morris and T. Harmon, J. Reg. Sci., 5, 1 (2017).
- F.R. Emily Guo, J. Environ. Anal. Toxicol., 5, 1 (2014); https://doi.org/10.4172/2161-0525.1000249
References
S. Singh, V. Kumar, S. Datta, A.B. Wani, D.S. Dhanjal, R. Romero and J. Singh, Environ. Chem. Lett., 18, 663 (2020); https://doi.org/10.1007/s10311-020-00969-z
C.M. Benbrook, Environ. Sci. Eur., 28, 3 (2016); https://doi.org/10.1186/s12302-016-0070-0
http://www.weedscience.org/ (Accessed on 22.01.2022).
M.C. Arregui, A. Lenardón, D. Sanchez, M.I. Maitre, R. Scotta and S. Enrique, Pest Manag. Sci., 60, 163 (2004); https://doi.org/10.1002/ps.775
S.H. Bai and S.M. Ogbourne, Environ. Sci. Pollut. Res. Int., 23, 18988 (2016); https://doi.org/10.1007/s11356-016-7425-3
T. Shushkova, I. Ermakova and A. Leontievsky, Biodegradation, 21, 403 (2010); https://doi.org/10.1007/s10532-009-9310-y
M. Pérez Rodríguez, C. Melo, E. Jiménez and J. Dussán, Agriculture, 9, 217 (2019); https://doi.org/10.3390/agriculture9100217
L. Simonsen, I.S. Fomsgaard, B. Svensmark and N.H. Spliid, J. Environ. Sci. Health B, 43, 365 (2008); https://doi.org/10.1080/03601230802062000
W.M. Farina, M.S. Balbuena, L.T. Herbert, C. Mengoni Goñalons and D.E. Vázquez, Insects, 10, 354 (2019); https://doi.org/10.3390/insects10100354
R.M. Mann and J.R. Bidwell, Arch. Environ. Contam. Toxicol., 36, 193 (1999); https://doi.org/10.1007/s002449900460
V. Langiano and C.B.R. Martinez, Comp. Biochem. Physiol. C Toxicol. Pharmacol., 147, 222 (2008); https://doi.org/10.1016/j.cbpc.2007.09.009
N.K. Neskovic, V. Poleksi, I. Elezovi, V. Karan and M. Budimir, Bull. Environ. Contam. Toxicol., 56, 295 (1996); https://doi.org/10.1007/s001289900044
S. Richard, S. Moslemi, H. Sipahutar, N. Benachour and G.-E. Seralini, Environ. Health Perspect., 113, 716 (2005); https://doi.org/10.1289/ehp.7728
V.J. Koller, M. Fürhacker, A. Nersesyan, M. Mišík, M. Eisenbauer and S. Knasmueller, Arch. Toxicol., 86, 805 (2012); https://doi.org/10.1007/s00204-012-0804-8
N. Chamkasem, C. Morris and T. Harmon, J. Reg. Sci., 5, 1 (2017).
F.R. Emily Guo, J. Environ. Anal. Toxicol., 5, 1 (2014); https://doi.org/10.4172/2161-0525.1000249