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Vol. 34 No. 7 (2022): Vol 34 Issue 7, 2022

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Synthesis of Nickel Oxide Nanoparticles from Syzygium cumini Plant Fruit Pulp Extract: Study of their Antibacterial, Antifungal and Cytotoxic Activities on CHO Cells

https://doi.org/10.14233/ajchem.2022.23750
Lalitha Ammadu Kolahalam
Department of Chemistry, Koneru Lakshmaiah Education Foundation, Green Fields, Vaddeswaram, Guntur 522502, India
K.R.S. Prasad
Department of Chemistry, Koneru Lakshmaiah Education Foundation, Green Fields, Vaddeswaram, Guntur 522502, India
P. Murali Krishna
Department of Chemistry, Ramaiah Institute of Technology (Autonomous Institute, Affiliated to VTU), Bangalore-560054, India
N. Supraja
Nanotechnology Laboratory, Acharya N.G. Ranga Agricultural University, Tirupati-517502, India

Corresponding Author(s) : K.R.S. Prasad

krsprasad_fed@kluniversity.in

Asian Journal of Chemistry, Vol. 34 No. 7 (2022): Vol 34 Issue 7, 2022

Abstract

The nickel oxide nanoparticles were synthesized using Syzygium cumini plant fruit pulp in a simple, ecofriendly and cost-effective procedure using the green chemistry route. The prepared nickel oxide nanoparticles were characterized by UV-visible (UV-Vis), Fourier transform infrared (FT-IR) spectroscopy, powder X-ray diffraction spectrometry (XRD), zeta potential (ZE), particle size (DLS), field emission scanning electron microscope (FE-SEM) analysis. The synthesized nanoparticles showed on an average of 16 to 31 nm in size. The synthesized nanoparticles were tested on several Gram-positive and Gram-negative bacteria and also on fungi, which showed less toxicity to them. Finally, the synthesized nanoparticles cytotoxic activity was tested on Chinese Hamster Ovary (CHO) cell lines, which showed cytotoxicity with IC50 value of 2.66 μg/mL.

Keywords

Nickel oxide nanoparticles Syzygium cumini Antibacterial activity Antifungal activity Cytotoxic activity
Ammadu Kolahalam, L., Prasad, K., Murali Krishna, P., & Supraja, N. (2022). Synthesis of Nickel Oxide Nanoparticles from Syzygium cumini Plant Fruit Pulp Extract: Study of their Antibacterial, Antifungal and Cytotoxic Activities on CHO Cells. Asian Journal of Chemistry, 34(7), 1735–1741. https://doi.org/10.14233/ajchem.2022.23750
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