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Vol. 34 No. 6 (2022): Vol 34 Issue 6

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p-TSA Catalyzed Synthesis of Tetrahydrobenzo[g]quinolines via Multicomponent Reaction using Pyrazole Aldehyde, Lawsone, β-Ketoesters and Ammonium Acetate

https://doi.org/10.14233/ajchem.2022.23686
Kittappa Gunasundari
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi-613503, India
Selvaraj Jayanthi
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi-613503, India
Sreedharan Helen Perci
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi-613503, India
Moorthy Vetriselvan
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi-613503, India
Manickam Pramesh
PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi-613503, India

Corresponding Author(s) : Manickam Pramesh

mprameshchemistry@gmail.com

Asian Journal of Chemistry, Vol. 34 No. 6 (2022): Vol 34 Issue 6

Abstract

An efficient protocol has been developed for the multicomponent synthesis of tetrahydrobenzo[g]quinoline-3-carboxylate derivatives using p-toluenesulfonic acid (p-TSA) as catalyst through one-pot four component condensation reaction of pyrazole aldehyde, Lawsone, β-ketoesters and ammonium acetate in ethanol. The synthesized compounds were characterized by spectroscopic techniques.

Keywords

Tetrahydrobenzoquinoline Pyrazole aldehydes Lawsone p-Toluenesulfonic acid
Gunasundari, K., Jayanthi, S., Helen Perci, S., Vetriselvan, M., & Pramesh, M. (2022). p-TSA Catalyzed Synthesis of Tetrahydrobenzo[g]quinolines via Multicomponent Reaction using Pyrazole Aldehyde, Lawsone, β-Ketoesters and Ammonium Acetate. Asian Journal of Chemistry, 34(6), 1439–1442. https://doi.org/10.14233/ajchem.2022.23686
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