Issue

Vol. 34 No. 12 (2022): Vol 34 Issue 12, 2022

Copyright (c) 2022 AJC

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Antibacterial, Anticancer, Catalytic and Antioxidant Activities of Green Synthesized Silver Nanoparticles Derived from Alternanthera sessilis Leaf Extract

https://doi.org/10.14233/ajchem.2022.23980
B. Hari Babu
Department of Chemistry, M.A.L.D. Government Degree College (Affiliated to Palamuru University), Gadwal-509125, India
G. Vijaya Lakshmi
Department of Chemistry, University College for Women, Affiliated to Osmania University, Koti, Hyderabad-500009, India

Corresponding Author(s) : B. Hari Babu

harirk95@gmail.com

Asian Journal of Chemistry, Vol. 34 No. 12 (2022): Vol 34 Issue 12, 2022

Abstract

The current study evaluates the biogenesis of silver nanoparticles (Ag NPs) utilizing an aqueous extract of Alternanthera sessilis (Linn.) leaf. Biological nanoparticle production has recently gained appeal due to its eco-friendliness, simplicity, cost-effectiveness, non-hazardous nature and difficult circumstances. Aqueous extract of Alternanthera sessilis leaf contains terpenoids, carbohydrates and flavonoids to convert metal ions into metal and so stabilize the resultant nanoparticles. The UV-visible spectrophotometer obtained a distinctive peak at 420 nm, the XRD validated the crystalline FCC nature of biogenic Ag NPs and the FTIR and zeta-potential (± 14) tests revealed that phyto-chemicals were responsible for reduction and stabilization of Ag NPs. TEM examination revealed a spherical form and size of about 24 nm. The biogenic Ag NPs displayed intriguing dose-dependent antioxidant activity, with an EC50 percent of 69.9g/mL and a maximum activity of 66.36 at 150 μg/mL against DPPH, as well as considerable catalytic activity against Eosin-Y red dye, 84% of Eosin-Y dye destroyed after 60 min. Furthermore, the experiments demonstrated that Ag NPs were more effective against Gram-negative bacteria than Gram-positive bacteria and also show the anticancer activity against Hela cells and breast cancer cell line (MCF-7).The anticancer activity is more potent in higher concentrations.

Keywords

Silver nanoparticles Alternanthera sessilis (Linn.) Biological activities Catalytic activity Phytochemicals
Hari Babu, B., & Vijaya Lakshmi, G. (2022). Antibacterial, Anticancer, Catalytic and Antioxidant Activities of Green Synthesized Silver Nanoparticles Derived from Alternanthera sessilis Leaf Extract. Asian Journal of Chemistry, 34(12), 3286–3292. https://doi.org/10.14233/ajchem.2022.23980
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. S. Patil and R. Chandrasekaran, J. Genet. Eng. Biotechnol., 18, 67 (2020); https://doi.org/10.1186/s43141-020-00081-3
  2. M. Shah, D. Fawcett, S. Sharma, S.K. Tripathy and G.E.J. Poinern, Materials, 8, 7278 (2015); https://doi.org/10.3390/ma8115377
  3. S. Patil and R. Chandrasekaran, J. Genet. Eng. Biotechnol., 18, 67 (2020); https://doi.org/10.1186/s43141-020-00081-3
  4. A. Albanese, P.S. Tang and W.C.W. Chan, Ann. Rev. Biomed. Eng., 14, 1 (2012); https://doi.org/10.1146/annurev-bioeng-071811-150124
  5. A. Mishra, S. Singla and A.K. Barui, Biogenic Nanoparticles for Cancer Theranostics, In: Micro and Nano Technologies, Elsevier, pp. 123-140 (2021); https://doi.org/10.1016/B978-0-12-821467-1.00011-2
  6. R.M. Slawson, J.T. Trevors and H. Lee, Arch. Microbiol., 158, 398 (1992); https://doi.org/10.1007/BF00276299
  7. G. Zhao and S.E. Stevens Jr., Biometals, 11, 27 (1998); https://doi.org/10.1023/A:1009253223055
  8. M.A. Khalil, G.M. El Maghraby, F.I. Sonbol, N.G. Allam, P.S. Ateya and S.S. Ali, Front. Microbiol., 12, 648560 (2021); https://doi.org/10.3389/fmicb.2021.648560
  9. A. Almatroudi, Open Life Sci., 15, 819 (2020); https://doi.org/10.1515/biol-2020-0094
  10. A. Roy and N. Bharadvaja, Biomimetic Nanobiomater., 8, 130 (2019); https://doi.org/10.1680/jbibn.18.00036
  11. J. Singh, T. Dutta, K.-H. Kim, M. Rawat, P. Samddar and P. Kumar, J. Nanobiotechnol., 16, 84 (2018); https://doi.org/10.1186/s12951-018-0408-4
  12. M. Ndikau, N.M. Noah, D.M. Andala and E. Masika, Int. J. Anal. Chem., 2017, 1 (2017); https://doi.org/10.1155/2017/8108504
  13. R.K. Singla, V. Dhir, R. Madaan, D. Kumar, S. Singh Bola, M. Bansal, S. Kumar, A.K. Dubey, S. Singla and B. Shen, Front. Pharmacol., 13, 769111 (2022); https://doi.org/10.3389/fphar.2022.769111
  14. L. Qian, W. Su, Y. Wang, M. Dang, W. Zhang and C. Wang, Artif. Cells Nanomed. Biotechnol., 47, 1173 (2019); https://doi.org/10.1080/21691401.2018.1549064
  15. C.E. Escárcega-González, J.A. Garza-Cervantes, A. VázquezRodríguez, L.Z. Montelongo-Peralta, M.T. Treviño-González, E. Díaz Barriga Castro, E.M. Saucedo-Salazar, R.M. Chávez Morales, D.I. Regalado-Soto, F.M. Treviño-González, J.L. Carrazco Rosales, R. Villalobos Cruz and J.R. Morones-Ramirez, Int. J. Nanomedicine, 13, 2349 (2018); https://doi.org/10.2147/IJN.S160605
  16. V.K. Vidhu and D. Philip, Micron, 56, 54 (2014); https://doi.org/10.1016/j.micron.2013.10.006
  17. L.L. Mensor, F.S. Menezes, G.G. Leitão, A.S. Reis, T.C. Santos, C.S. Coube and S.G. Leitão, Phytother. Res., 15, 127 (2001); https://doi.org/10.1002/ptr.687
  18. A.K. Keshari, R. Srivastava, P. Singh, V.B. Yadav and G. Nath, J. Ayurveda Integr. Med., 11, 37 (2020); https://doi.org/10.1016/j.jaim.2017.11.003
  19. M.S. Majoumouo, N.R.S. Sibuyi, M.B. Tincho, M. Mbekou, F.F. Boyom and M. Meyer, Int. J. Nanomedicine, 14, 9031 (2019); https://doi.org/10.2147/IJN.S223447
  20. Hemlata, P.R. Meena, A.P. Singh and K.K. Tejavath, ACS Omega, 5, 5520 (2020); https://doi.org/10.1021/acsomega.0c00155.
  21. N. Yang and W. Li, Ind. Crops Prod., 48, 81 (2013); https://doi.org/10.1016/j.indcrop.2013.04.001
  22. L.B. Anigol, J.S. Charantimath and P.M. Gurubasavaraj, Org. Med. Chem., 3, 1 (2017); https://doi.org/10.19080/OMCIJ.2017.03.555622
  23. M.S. Samuel, M. Ravikumar, A. John J., E. Selvarajan, H. Patel, P.S. Chander, J. Soundarya, S. Vuppala, R. Balaji and N. Chandrasekar, Catalysts, 12, 459 (2022); https://doi.org/10.3390/catal12050459
  24. S. Raj, R. Trivedi and V. Soni, Surfaces, 5, 67 (2021); https://doi.org/10.3390/surfaces5010003
  25. K. Gopinath, S. Gowri and A. Arumugam, J. Nanostructure Chem., 3, 68 (2013); https://doi.org/10.1186/2193-8865-3-68
  26. S.M. Rakib-Uz-Zaman, E.H. Apu, M.N. Muntasir, S.A. Mowna, M.G. Khanom, S.S. Jahan, N. Akter, M.A.R. Khan, N.S. Shuborna, S.M. Shams and K. Khan, Challenges, 13, 18 (2022); https://doi.org/10.3390/challe13010018
  27. J.K. Patra and K. Baek, J. Nanomater. Synth., 2014, 417305 (2014); https://doi.org/10.1155/2014/417305
  28. R. Mata, J.R. Nakkala and S.R. Sadras, Colloids Surf. B Biointerfaces, 128, 276 (2015); https://doi.org/10.1016/j.colsurfb.2015.01.052
  29. E. Urnukhsaikhan, B.E. Bold, A. Gunbileg, N. Sukhbaatar and T. Mishig-Ochir, Sci. Rep., 11, 21047 (2021); https://doi.org/10.1038/s41598-021-00520-2
  30. L. Budama, B.A. Çakir, Ö. Topel and N. Hoda, Chem. Eng. J., 228, 489 (2013); https://doi.org/10.1016/j.cej.2013.05.018
  31. K. Anandalakshmi, J. Venugobal and V. Ramasamy, Appl. Nanosci., 6, 399 (2016); https://doi.org/10.1007/s13204-015-0449-z
  32. H. Padalia, P. Moteriya and S. Chanda, Arab. J. Chem., 8, 732 (2015); https://doi.org/10.1016/j.arabjc.2014.11.015
  33. T.A. Jorge de Souza, L.R. Rosa Souza and L.P. Franchi, Ecotoxicol. Environ. Saf., 171, 691 (2019); https://doi.org/10.1016/j.ecoenv.2018.12.095
  34. Y. Sun, B. Gates, B. Mayers and Y. Xia, Nano Lett., 2, 165 (2002); https://doi.org/10.1021/nl010093y
  35. K. Mohan Kumar, M. Sinha, B.K. Mandal, A.R. Ghosh, K. Siva Kumar and P. Sreedhara Reddy, Spectrochim. Acta A Mol. Biomol. Spectrosc., 91, 228 (2012); https://doi.org/10.1016/j.saa.2012.02.001
  36. M.J. Khan, K. Shameli, A.Q. Sazili, J. Selamat and S. Kumari, Molecules, 24, 719 (2019); https://doi.org/10.3390/molecules24040719
  37. R. Karthik, M. Govindasamy, S.M. Chen, P. Muthukrishnan, Y.H. Cheng, S. Padmavathy and A. Elangovan, J. Photochem. Photobiol. B, 170, 164 (2017); https://doi.org/10.1016/j.jphotobiol.2017.03.018
  38. S. Rajeshkumar, S. Menon, S. Venkat Kumar, M.M. Tambuwala, H.A. Bakshi, M. Mehta, S. Satija, G. Gupta, D.K. Chellappan, L. Thangavelu and K. Dua, J. Photochem. Photobiol. B, 197, 111531 (2019); https://doi.org/10.1016/j.jphotobiol.2019.111531
Read More
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 0 Download : 0