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Chemical Composition and Biological Activities of Essential Oil of Elsholtzia ciliata obtained at Central Highlands of Vietnam’s Two Seasons
Corresponding Author(s) : Vu Thi Thu Le
Asian Journal of Chemistry,
Vol. 34 No. 11 (2022): Vol 34 Issue 11, 2022
Abstract
From the essential oil of the whole plant from Elsholtzia ciliata, obtained by hydrodistillation and then using gas chromatography/mass spectrometry to analyze and identify 42 constituents, carveol (26.89%) and z-citral (29.35%) main contents (collected in the dry season time); and 46 constituents, cis-ocimene (17.95%), carveol (14.84%), Z-citral (17.01%), isocaryophyllene (13.19%) and trans-caryophyllene (9.76%) as main contents (collected in the rainy season time). The major essential oils in dry season exhibited good inhibition activity on the Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Candida albicans with MIC value of 200 μg/mL; exhibited weak cytotoxic activity on the PC-3 line (IC50 66.34 μg/mL) and A549 line (IC50 93.11 μg/mL). The essential oils in rainy season exhibited good inhibition activity on the Escherichia coli, Bacillus subtillis and Saccharomyces cerevisiae with MIC value of 200 μg/mL and Candida albicans with MIC value of 100 μg/mL; displayed good cytotoxic activity on the PC-3 line (IC50 30.62 μg/mL) and Hep-G2 line (IC50 22.78 μg/mL), however have weak cytotoxic activity on the A549 line (IC50 85.35 μg/mL).
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- L. Pudziuvelyte, M. Stankevicius, A. Maruska, O. Ragazinskiene, V. Petrikaite, G. Draksiene and J. Bernatoniene, Ind. Crops Prod., 107, 90 (2017); https://doi.org/10.1016/j.indcrop.2017.05.040
- P. H. Ho, An Illustrated Flora of Vietnam, Youth Publication: HCM city, Ed.: 2, vol. II, pp. 859-861 (2003) (In Vietnamese).
- N.T. Ban, Checklist of Plant Species of Vietnam, Agriculture Publishing House, Hanoi, vol. III, p. 312 (2003) (In Vietnamese).
- L.Ð. Moi, L.Ð. Cu, T.M. Hoi, T.H. Thai and N.K. Ban, Essential Oil Plant Resources in Vietnam, Agriculture Publishing House, Hanoi, vol. II (2002) (In Vietnamese).
- D.T. Loi, Vietnamese Medicinal Plants and Remedies/Substances, Health Publishing House: Ha Noi, Ed.: 12 (2004) (In Vietnamese).
- E.A. Korolyuk, W. König and A.V. Tkachevc, Chemistry of Plant Raw Materials, 1, 31 (2002) (In Russian).
- D.T.T. Nhan and L.T. Huyen, J. Sci., 2, 85 (2017) (In Vietnamese).
- N.X. Dung, L. Van Hac, L.H. Hai and P.A. Leclercq, J. Essent. Oil Res., 8, 107 (1996); https://doi.org/10.1080/10412905.1996.9700569
- F.M. DaMatta, A. Grandis, B.C. Arenque and M.S. Buckeridge, Food Res. Int., 7, 1814 (2010); https://doi.org/10.1016/j.foodres.2009.11.001
- V.A. Berghe and A.J. Vlietinck, Eds.: P.M. Dey, J.B. Harborne and K. Hostettman, Screening Methods for Antibacterial and Antiviral Agents from Higher Plants, In: Methods for Biochemistry, Academic Press: London, vol. 6, pp. 47-69 (1991).
- J. van Meerloo, G.J.L. Kaspers and J. Cloos, Methods in Mol. Bio., 731 (2011); https://doi.org/10.1007/978-1-61779-080-5_20
- T. Mosmann, J. Immunol. Methods, 65, 55 (1983); https://doi.org/10.1016/0022-1759(83)90303-4
- J. Ma, R.R. Xu, Y. Lu, D.F. Ren and J. Lu, J. Essent. Oil-Bear. Plants, 21, 556 (2018); https://doi.org/10.1080/0972060X.2017.1409657
References
L. Pudziuvelyte, M. Stankevicius, A. Maruska, O. Ragazinskiene, V. Petrikaite, G. Draksiene and J. Bernatoniene, Ind. Crops Prod., 107, 90 (2017); https://doi.org/10.1016/j.indcrop.2017.05.040
P. H. Ho, An Illustrated Flora of Vietnam, Youth Publication: HCM city, Ed.: 2, vol. II, pp. 859-861 (2003) (In Vietnamese).
N.T. Ban, Checklist of Plant Species of Vietnam, Agriculture Publishing House, Hanoi, vol. III, p. 312 (2003) (In Vietnamese).
L.Ð. Moi, L.Ð. Cu, T.M. Hoi, T.H. Thai and N.K. Ban, Essential Oil Plant Resources in Vietnam, Agriculture Publishing House, Hanoi, vol. II (2002) (In Vietnamese).
D.T. Loi, Vietnamese Medicinal Plants and Remedies/Substances, Health Publishing House: Ha Noi, Ed.: 12 (2004) (In Vietnamese).
E.A. Korolyuk, W. König and A.V. Tkachevc, Chemistry of Plant Raw Materials, 1, 31 (2002) (In Russian).
D.T.T. Nhan and L.T. Huyen, J. Sci., 2, 85 (2017) (In Vietnamese).
N.X. Dung, L. Van Hac, L.H. Hai and P.A. Leclercq, J. Essent. Oil Res., 8, 107 (1996); https://doi.org/10.1080/10412905.1996.9700569
F.M. DaMatta, A. Grandis, B.C. Arenque and M.S. Buckeridge, Food Res. Int., 7, 1814 (2010); https://doi.org/10.1016/j.foodres.2009.11.001
V.A. Berghe and A.J. Vlietinck, Eds.: P.M. Dey, J.B. Harborne and K. Hostettman, Screening Methods for Antibacterial and Antiviral Agents from Higher Plants, In: Methods for Biochemistry, Academic Press: London, vol. 6, pp. 47-69 (1991).
J. van Meerloo, G.J.L. Kaspers and J. Cloos, Methods in Mol. Bio., 731 (2011); https://doi.org/10.1007/978-1-61779-080-5_20
T. Mosmann, J. Immunol. Methods, 65, 55 (1983); https://doi.org/10.1016/0022-1759(83)90303-4
J. Ma, R.R. Xu, Y. Lu, D.F. Ren and J. Lu, J. Essent. Oil-Bear. Plants, 21, 556 (2018); https://doi.org/10.1080/0972060X.2017.1409657