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Vol. 37 No. 9 (2025): Vol 37 Issue 9, 2025

Copyright (c) 2025 Lanciné Traoré

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Enhanced Extraction of Polyphenols, Flavonoids and Antioxidant Activity from Cynometra ananta Stem Bark using Ultrasonic Method: A Kinetic Modelling Approach

https://doi.org/10.14233/ajchem.2025.34403
Lanciné Traoré
UFR-Sciences et Technologies, Université de Man, BP 20 Man, Côte d'Ivoire; Laboratoire de Chimie Bio Organique et de Substances Naturelles, UFR-SFA, Université Nangui ABROGOUA, 02 bp 801 Abidjan 02, Côte d'Ivoire
https://orcid.org/0000-0001-8754-7903
Kamagate Mahamadou
UFR-Sciences et Technologies, Université de Man, BP 20 Man, Côte d'Ivoire
Gnougon Nina Coulibaly
UFR-Sciences et Technologies, Université de Man, BP 20 Man, Côte d'Ivoire
Yao Arthur Kouassi
UFR-Sciences et Technologies, Université de Man, BP 20 Man, Côte d'Ivoire
Yves-Alain Bekro
Laboratoire de Chimie Bio Organique et de Substances Naturelles, UFR-SFA, Université Nangui ABROGOUA, 02 bp 801 Abidjan 02, Côte d'Ivoire

Corresponding Author(s) : Lanciné Traoré

lancine.traore@univ-man.edu.ci

Asian Journal of Chemistry, Vol. 37 No. 9 (2025): Vol 37 Issue 9, 2025

Abstract

Cynometra ananta stem bark is rich in bioactive phenolic compounds with antioxidant potential. This study evaluated the efficiency of ultrasound-assisted extraction (UAE) in comparison to conventional maceration at various solid-to-liquid ratios (1:60, 1:80, and 1:120 g/mL) and described the extraction kinetics using a second-order kinetic equation. The highest polyphenol yield was achieved with UAE at a 1/60 ratio (482 µg GAE/mg DM), surpassing maceration (420 µg GAE/mg DM). Flavonoid content also increased significantly with UAE, reaching 14.18 µg QE/mg DM versus 7.72 μg QE/mg DM with maceration. Antioxidant activity (FRAP) was enhanced by ultrasound, with a saturation concentration of 238 µg Trolox/mg DM. Kinetic modeling showed excellent correlation (R2 > 0.99) across all conditions. The improved performance of UAE is attributed to enhanced mass transfer, solvent penetration and cavitation effects. These findings highlight ultrasound-assisted extraction as a powerful, cost-effective method for recovering polyphenols and flavonoids from C. ananta, with promising implications for natural antioxidant production.

Keywords

Cynometra ananta Ultrasound-assisted extraction Polyphenols Flavonoids Antioxidant activity Second-order kinetics
(1)
Traoré, L.; Mahamadou, K.; Coulibaly, G. N.; Kouassi, Y. A.; Bekro, Y.-A. Enhanced Extraction of Polyphenols, Flavonoids and Antioxidant Activity from Cynometra Ananta Stem Bark Using Ultrasonic Method: A Kinetic Modelling Approach. ajc 2025, 37, 2307-2312.
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