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Oxidation of Cinacalcet Hydrochloride by Chloramine-B in Acid Medium: A Kinetic and Mechanistic Study
Corresponding Author(s) : Nichhapurada Kallesha
Asian Journal of Chemistry,
Vol. 33 No. 9 (2021): Vol 33 Issue 9, 2021
Abstract
Kinetic and mechanistic study of cinacalcet hydrochloride by chloramine-B (CAB) in HCl medium at 308 K was the aim of this work. Analyzed the reaction at five different temperatures and determined the thermodynamic parameters using Arrhenius plots. The reaction had a stoichiometry of 1:2 and characterized the oxidation product using chromatographic and spectroscopic methods. The rate law is deduced from the marked effects, which were accompanied by plausible mechanisms.
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- N. Nanda, S.M. Mayanna and N.M. Madegowda, Int. J. Chem. Kinet., 31, 153 (1999); https://doi.org/10.1002/(SICI)1097-4601(1999)31:2<153::AIDKIN8>3.0.CO;2-O
- A. Fantinati, V. Zanirato, P. Marchetti and C. Trapella, ChemistryOpen, 9, 100 (2020); https://doi.org/10.1002/open.201900220
- E. Kolvari, A. Ghorbani-Choghamarani, P. Salehi, F. Shirini and M.A. Zolfigol, J. Iran. Chem. Soc., 4, 126 (2007).
- H.-Y. Xiong, X. Pannecoucke and T. Besset, Org. Chem. Front., 3, 620 (2016); https://doi.org/10.1039/C6QO00064A
- K.S. Rangappa, J. Phys. Org. Chem., 14, 684 (2001); https://doi.org/10.1002/poc.415
- W. Gan, Y. Ge, Y. Zhong and X. Yang, Environ. Sci.: Water Res. Technol., 6, 2287 (2020); https://doi.org/10.1039/D0EW00231C
- J.P. Puttaswamy, J.P. Shubha and R.V. Jagadeesh, Transition Met. Chem., 32, 991 (2007); https://doi.org/10.1007/s11243-007-0271-x
- K.N. Mohana, N. Prasad and K.M.L. Rai, Monatsh. Chem., 139, 1203 (2008); https://doi.org/10.1007/s00706-008-0909-1
- Puttaswamy, R.V. Jagadeesh and N. Vaz, Cent. Eur. J. Chem., 3, 326 (2005); https://doi.org/10.2478/BF02476000
- V.R. Arava, L. Gorentla and P.K. Dubey, Beilstein J. Org. Chem., 8, 1366 (2012); https://doi.org/10.3762/bjoc.8.158
- A.K. Choulwar, A. Ashish and C. Meena, Ann. Biol. Res., 2, 35 (2011).
- H.M. Rothe, O. Liangos, P. Bigger, A. Petermann and A. Ketteler, Int. J. Endocrinol., 2011, 415719 (2011); https://doi.org/10.1155/2011/415719
- J. Cunningham, M. Danese, K. Olson, P. Klassen and G.M. Chertow, Kidney Int., 68, 1793 (2005); https://doi.org/10.1111/j.1523-1755.2005.00596.x
- M. Krishnan, S.L. Karunanidhi, G. Sola and Y. Akshitha, Ind. J. Res. Pharm. Biotechnol., 1, 346 (2013).
- R. Bhushan and R. Dubey, Biomed. Chromatogr., 25, 674 (2011); https://doi.org/10.1002/bmc.1502
- Puttaswamy and R.V. Jagadeesh, Cent. Eur. J. Chem., 3, 482 (2005); https://doi.org/10.2478/BF02479277
- J.P. Shubha and Puttaswamy, Adv. Phys. Chem., 2014, 1 (2014); https://doi.org/10.1155/2014/238984
- N. Nanda and P. Kumar, Int. J. Pharm. Sci. Res., 5, 3886 (2014).
- S. Malini, K. Raj, N. Nanda, Int. J. Pharm. Rev. Res., 25, 290 (2014).
- J.P. Shubha, V. Kotabagi and P. Puttaswamy, Bull. Korean Chem. Soc., 33, 3539 (2012); https://doi.org/10.5012/bkcs.2012.33.11.3539
References
N. Nanda, S.M. Mayanna and N.M. Madegowda, Int. J. Chem. Kinet., 31, 153 (1999); https://doi.org/10.1002/(SICI)1097-4601(1999)31:2<153::AIDKIN8>3.0.CO;2-O
A. Fantinati, V. Zanirato, P. Marchetti and C. Trapella, ChemistryOpen, 9, 100 (2020); https://doi.org/10.1002/open.201900220
E. Kolvari, A. Ghorbani-Choghamarani, P. Salehi, F. Shirini and M.A. Zolfigol, J. Iran. Chem. Soc., 4, 126 (2007).
H.-Y. Xiong, X. Pannecoucke and T. Besset, Org. Chem. Front., 3, 620 (2016); https://doi.org/10.1039/C6QO00064A
K.S. Rangappa, J. Phys. Org. Chem., 14, 684 (2001); https://doi.org/10.1002/poc.415
W. Gan, Y. Ge, Y. Zhong and X. Yang, Environ. Sci.: Water Res. Technol., 6, 2287 (2020); https://doi.org/10.1039/D0EW00231C
J.P. Puttaswamy, J.P. Shubha and R.V. Jagadeesh, Transition Met. Chem., 32, 991 (2007); https://doi.org/10.1007/s11243-007-0271-x
K.N. Mohana, N. Prasad and K.M.L. Rai, Monatsh. Chem., 139, 1203 (2008); https://doi.org/10.1007/s00706-008-0909-1
Puttaswamy, R.V. Jagadeesh and N. Vaz, Cent. Eur. J. Chem., 3, 326 (2005); https://doi.org/10.2478/BF02476000
V.R. Arava, L. Gorentla and P.K. Dubey, Beilstein J. Org. Chem., 8, 1366 (2012); https://doi.org/10.3762/bjoc.8.158
A.K. Choulwar, A. Ashish and C. Meena, Ann. Biol. Res., 2, 35 (2011).
H.M. Rothe, O. Liangos, P. Bigger, A. Petermann and A. Ketteler, Int. J. Endocrinol., 2011, 415719 (2011); https://doi.org/10.1155/2011/415719
J. Cunningham, M. Danese, K. Olson, P. Klassen and G.M. Chertow, Kidney Int., 68, 1793 (2005); https://doi.org/10.1111/j.1523-1755.2005.00596.x
M. Krishnan, S.L. Karunanidhi, G. Sola and Y. Akshitha, Ind. J. Res. Pharm. Biotechnol., 1, 346 (2013).
R. Bhushan and R. Dubey, Biomed. Chromatogr., 25, 674 (2011); https://doi.org/10.1002/bmc.1502
Puttaswamy and R.V. Jagadeesh, Cent. Eur. J. Chem., 3, 482 (2005); https://doi.org/10.2478/BF02479277
J.P. Shubha and Puttaswamy, Adv. Phys. Chem., 2014, 1 (2014); https://doi.org/10.1155/2014/238984
N. Nanda and P. Kumar, Int. J. Pharm. Sci. Res., 5, 3886 (2014).
S. Malini, K. Raj, N. Nanda, Int. J. Pharm. Rev. Res., 25, 290 (2014).
J.P. Shubha, V. Kotabagi and P. Puttaswamy, Bull. Korean Chem. Soc., 33, 3539 (2012); https://doi.org/10.5012/bkcs.2012.33.11.3539