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Vol. 33 No. 8 (2021): Vol 33 Issue 8, 2021

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Study of Photophysico-chemical and Antimicrobial Photodynamic Properties of Visible Light Active Azometal(II) Complexes

https://doi.org/10.14233/ajchem.2021.23178
H.B. Teja
Department of P.G. Studies and Research in Industrial Chemistry, School of Chemical Science, Kuvempu University, Shankaragatta-577451, India
H.S. Bhojya Naik
Department of P.G. Studies and Research in Industrial Chemistry, School of Chemical Science, Kuvempu University, Shankaragatta-577451, India
P.H. Amith Nayak
Department of P.G. Studies and Research in Industrial Chemistry, School of Chemical Science, Kuvempu University, Shankaragatta-577451, India
M.C. Prabhakara
Department of P.G. Studies and Research in Industrial Chemistry, Sir M.V. Government Science College, Bommanakatte, Bhadravathi-577302, India

Corresponding Author(s) : H.S. Bhojya Naik

hsb_naik@rediffmail.com

Asian Journal of Chemistry, Vol. 33 No. 8 (2021): Vol 33 Issue 8, 2021

Abstract

The Co(II) and Mn(II) complexes with octahedral geometries of the type [Co(L)2(H2O)2] and [Mn(L)2(H2O)2] were synthesized and characterized by elemental analysis, FT-IR, UV-visible spectra, powered XRD and photoluminescence. Both metal(II) complexes were prepared with 4-[(Z)-(8-hydroxyquinolin-5-yl)diazenyl]-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one. The complexes were evaluated for in vitro antimicrobial photodynamic activity against Gram-positive, Gram-negative bacteria and fungi. The cell inhibition rate was found to be 80-96%. in vitro Cytotoxic studies were performed for the synthesized complexes against human melanoma (A-375) and human primary glioblastoma (U-87) cell lines by MTT assay where Co(II) complex showed potential inhibitory efficiency with IC50 value of 115 μg/mL when compared to Mn(II) complex.

Keywords

Metal (II) Complexes Azo dye Photosensitizer Advance photodynamic therapy Anticancer activity
Teja, H., Bhojya Naik, H., Amith Nayak, P., & Prabhakara, M. (2021). Study of Photophysico-chemical and Antimicrobial Photodynamic Properties of Visible Light Active Azometal(II) Complexes. Asian Journal of Chemistry, 33(8), 1709–1717. https://doi.org/10.14233/ajchem.2021.23178
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References
  1. Á. Juarranz, P. Jaén, F. Sanz-Rodríguez, J. Cuevas and S. González, Clin. Transl. Oncol., 10, 148 (2008); https://doi.org/10.1007/s12094-008-0172-2
  2. R.R. Allison, H.C. Mota and C.H. Sibata, Photodiagn. Photodyn. Ther., 1, 263 (2004); https://doi.org/10.1016/S1572-1000(04)00084-5
  3. R.R. Allison and C.H. Sibata, Photodiagn. Photodyn. Ther., 7, 61 (2010); https://doi.org/10.1016/j.pdpdt.2010.02.001
  4. L. Cizeková, A. Grolmusová, Z. Ipóthová, Z. Barbieriková, V. Brezová, L. Hunáková, J. Imrich, L. Janovec, I. Dovinová and H. Paulíková, Bioorg. Med. Chem., 22, 4684 (2014); https://doi.org/10.1016/j.bmc.2014.07.013
  5. A. Gasparetto, T.F. Lapinski, S.R. Zamuner, S. Khouri, L.P. Alves, E. Munin and M.J. Salvador, J. Photochem. Photobiol. B, 99, 15 (2010); https://doi.org/10.1016/j.jphotobiol.2010.01.009
  6. N. Barbero, S. Visentin and G. Viscardi, J. Photochem. Photobiol. Chem., 299, 38 (2015); https://doi.org/10.1016/j.jphotochem.2014.11.002
  7. A.P. Castano, T.N. Demidova and M.R. Hamblin, Photodiagn. Photodyn. Ther., 1, 279 (2004); https://doi.org/10.1016/S1572-1000(05)00007-4
  8. M.S. Baptista and M. Wainwright, J. Med. Biol. Res., 44, 1 (2011); https://doi.org/10.1590/S0100-879X2010007500141
  9. M. Managa, E.K. Amuhaya and T. Nyokong, Spectrochim. Acta A Mol. Biomol. Spectrosc., 151, 867 (2015); https://doi.org/10.1016/j.saa.2015.06.088
  10. Y.D. Kim, J.H. Cho, C.R. Park, J.-H. Choi, C. Yoon and J.P. Kim, Dyes Pigments, 89, 1 (2011); https://doi.org/10.1016/j.dyepig.2010.07.008
  11. V. Kumar, M. Gohain, J.H. Van Tonder, B.C.B. Bezuindenhoudt, S. Ponra, O.M. Ntwaeaborwa and H.C. Swart, Opt. Mater., 50, 275 (2015); https://doi.org/10.1016/j.optmat.2015.11.009
  12. N.C. Warshakoon, J. Sheville, R.T. Bhatt, W. Ji, J.L. Mendez-Andino, K.M. Meyers, N. Kim, J.A. Wos, C. Mitchell, J.L. Paris, B.B. Pinney, O. Reizes and X.E. Hu, Bioorg. Med. Chem. Lett., 16, 5207 (2006); https://doi.org/10.1016/j.bmcl.2006.07.006
  13. R. Teran, R. Guevara, J. Mora, L. Dobronski, O. Barreiro-Costa, T. Beske, J. Pérez-Barrera, R. Araya-Maturana, P. Rojas-Silva, A. Poveda and J. Heredia-Moya, Molecules, 24, 2696 (2019); https://doi.org/10.3390/molecules24152696
  14. S. Kumar, S. Bawa and H. Gupta, Mini Rev. Med. Chem., 9, 1648 (2009); https://doi.org/10.2174/138955709791012247
  15. H.-R. Zhang, K.-B. Huang, Z.-F. Chen, Y.-C. Liu, Y.-N. Liu, T. Meng, Q.-P. Qin, B.-Q. Zou and H. Liang, MedChemComm, 7, 806, (2016); https://doi.org/10.1039/C6MD00073H
  16. M.C. Prabahkara and H.S. Bhojya Naik, Biometals, 21, 675 (2008); https://doi.org/10.1007/s10534-008-9152-9
  17. C.N. Sudhamani, H.S. Bhojya Naik and D. Girija, Synth. React. Inorg. Met.-Org. Nano-Met. Chem., 42, 518 (2012); https://doi.org/10.1080/15533174.2011.613439
  18. M.A. Gouda, H.F. Eldien, M.M. Girges and M.A. Berghot, J. Saudi Chem. Soc., 20, 151 (2016); https://doi.org/10.1016/j.jscs.2012.06.004
  19. C.H. Kim, E.S. Lee, S.M. Kang, E. de Josselin de Jong and B.-I. Kim, Photodiagn. Photodyn. Ther., 18, 279 (2017); https://doi.org/10.1016/j.pdpdt.2017.03.015
  20. A. Vt, P. Paramanantham, S.L. Sb, A. Sharan, M.H. Alsaedi, T.M.S. Dawoud, S. Asad and S. Busi, Photodiagn. Photodyn. Ther., 24, 300 (2018); https://doi.org/10.1016/j.pdpdt.2018.10.013
  21. C.N. Sudhamani, H.S. Bhojya Naik, K.R.S. Gowda, M. Giridhar, D. Girija and P.N.P. Kumar, Med. Chem. Res., 26, 1160 (2017); https://doi.org/10.1007/s00044-017-1831-z
  22. S. Ali, V. Singh, P. Jain and V. Tripathi, J. Saudi Chem. Soc., 23, 52 (2019); https://doi.org/10.1016/j.jscs.2018.04.005
  23. M. Zhu, J. Liu, J. Su, B. Meng, Y. Feng, B. Jia, T. Peng, Z. Qi and E. Gao, Appl. Organomet. Chem., 33, 4676 (2019); https://doi.org/10.1002/aoc.4676
  24. P. Vijayan, P. Viswanathamurthi, K. Velmurugan, R. Nandhakumar, M.D. Balakumaran, P.T. Kalaichelvan and J.G. Malecki, RSC Adv., 5, 103321 (2015); https://doi.org/10.1039/C5RA18568H
  25. A. De, H.P. Ray, P. Jain, H. Kaur and N. Singh, J. Mol. Struct., 1199, 126901 (2020); https://doi.org/10.1016/j.molstruc.2019.126901
  26. A.Y. Al-Dawood, N.M. El -Metwaly and H.A. El-Ghamry, J. Mol. Liq., 220, 311 (2016); https://doi.org/10.1016/j.molliq.2016.04.079
  27. V.A. Mamedov, V.R. Galimullina, N.A. Zhukova, S.F. Kadyrova, E.V. Mironova, I.K. Rizvanov and S.K. Latypov, Tetrahedron Lett., 55, 4319 (2014); https://doi.org/10.1016/j.tetlet.2014.06.023
  28. A. Saylam, Z. Seferoglu and N. Ertan, J. Mol. Liq., 195, 267 (2014); https://doi.org/10.1016/j.molliq.2014.02.027
  29. G. Karpiñska, A.P. Mazurek and J.C. Dobrowolski, J. Mol. Struct. THEOCHEM, 961, 101 (2010); https://doi.org/10.1016/j.theochem.2010.09.006
  30. M. Manjunath, A.D. Kulkarni, G.B. Bagihalli, S. Malladi and S.A. Patil, J. Mol. Struct., 1127, 314 (2016); https://doi.org/10.1016/j.molstruc.2016.07.123
  31. N. Venugopal, G. Krishnamurthy, H.S. Bhojyanaik and P. Murali Krishna, J. Mol. Struct., 1183, 37 (2019); https://doi.org/10.1016/j.molstruc.2019.01.031
  32. M.A. Ayoub, J. Mol. Struct., 1173, 17 (2018); https://doi.org/10.1016/j.molstruc.2018.06.051
  33. S.A.F. Rostom, I.M. El-Ashmawy, H.A. Abd El Razik, M.H. Badr and H.M.A. Ashour, Bioorg. Med. Chem., 17, 882 (2009); https://doi.org/10.1016/j.bmc.2008.11.035
  34. X. Li, Y. Wu, D. Gu and F. Gan, Dyes Pigments, 86, 182 (2010); https://doi.org/10.1016/j.dyepig.2010.01.002
  35. M.K.B. Break, M. Ibrahim M. Tahir, K.A. Crouse and T.-J. Khoo, Bioinorg. Chem. Appl., 2013, 362513 (2013); https://doi.org/10.1155/2013/362513
  36. S.M. Pradeepa, H.S. Bhojya Naik, B.V. Kumar, K.I. Priyadarsini, A. Barik and M.C. Prabhakara, Spectrochim. Acta A Mol. Biomol. Spectrosc., 141, 34 (2015); https://doi.org/10.1016/j.saa.2015.01.019
  37. S.M. Pradeepa, H.S. Bhojya Naik, B.V. Kumar, K.I. Priyadarsini, A. Barik, T.R. Ravikumar Naik and M.C. Prabhakara, Spectrochim. Acta A Mol. Biomol. Spectrosc., 115, 12 (2013); https://doi.org/10.1016/j.saa.2013.06.009
  38. K. Andiappan, A. Sanmugam, E. Deivanayagam, K. Karuppasamy, H.-S. Kim and D. Vikraman, Sci. Rep., 8, 3054 (2018); https://doi.org/10.1038/s41598-018-21366-1
  39. T. Manjuraj, G. Krishnamurthy, Y.D. Bodke, H.S.B. Naik and H.S. Anil Kumar, J. Mol. Struct., 1171, 481 (2018); https://doi.org/10.1016/j.molstruc.2018.06.055
  40. M. Sennappan, P.M. Krishna, R. Ranganathan and P. Sivakami Sundari, J. Mol. Struct., 1179, 86 (2019); https://doi.org/10.1016/j.molstruc.2018.10.087
  41. N.K. Chaudhary and P. Mishra, Bioinorg. Chem. Appl., 2017, 6927675 (2017); https://doi.org/10.1155/2017/6927675
  42. O.A.M. Ali, S.M. El-Medani, D.A. Ahmed and D.A. Nassar, Spectrochim. Acta A Mol. Biomol. Spectrosc., 144, 99 (2015); https://doi.org/10.1016/j.saa.2015.02.078
  43. Z. Sun, S. Zhou, H. Qiu, Y. Gu and Y. Zhao, RSC Adv., 8, 17073 (2018); https://doi.org/10.1039/C8RA02557F
  44. L.M. Tokubo, P.L. Rosalen, J. de Cássia Orlandi Sardi, I.A. Freires, M. Fujimaki, J.E. Umeda, P.M. Barbosa, G.O. Tecchio, N. Hioka, C.F. de Freitas and R.S. Suga Terada, Photodiagn. Photodyn. Ther., 23, 94 (2018); https://doi.org/10.1016/j.pdpdt.2018.05.004
  45. C.M. Cassidy, R.F. Donnelly, J.S. Elborn, N.D. Magee and M.M. Tunney, J. Photochem. Photobiol. B, 106, 95 (2012); https://doi.org/10.1016/j.jphotobiol.2011.10.010
  46. S. Leonard, P. M. Gannett, Y. Rojanasakul, D. Schwegler-Berry, V. Castranova, V. Vallyathan and X. Shi, J. Inorg. Biochem., 70, 239 (1998); https://doi.org/10.1016/S0162-0134(98)10022-3
  47. A. Hanakova, K. Bogdanova, K. Tomankova, K. Pizova, J. Malohlava, S. Binder, R. Bajgar, K. Langova, M. Kolar, J. Mosinger and H. Kolarova, Microbiol. Res., 169, 163 (2014); https://doi.org/10.1016/j.micres.2013.07.005
  48. Z. Yaghobi, Z. Rashidi Ranjbar and S. Gharbi, Polyhedron, 164, 176 (2019); https://doi.org/10.1016/j.poly.2019.02.039
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