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Vol. 33 No. 4 (2021): Vol 33 Issue 4

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Synthesis, Characterization, Antibacterial, Antifungal and Antimalarial Study of Mixed Ligand Metal Complexes Derived from Azo Quinoline with Thiosemicarbazone

https://doi.org/10.14233/ajchem.2021.23110
S.S. Borhade
Post Graduate Department of Chemistry, K.R.T. Arts, B.H. Commerce and A.M. Science College, Nashik-422002, India ; Department of Chemistry, S.M.B.S.T. College of Arts, Science and Commerce, Sangamner-422605, India
P.T. Tryambake
Post Graduate Department of Chemistry, K.R.T. Arts, B.H. Commerce and A.M. Science College, Nashik-422002, India ; Department of Chemistry, S.N. Arts, D.J.M. Commerce and B.N.S. Science College, Sangamner-422605, India

Corresponding Author(s) : P.T. Tryambake

pravintryambake21@rediffmail.com

Asian Journal of Chemistry, Vol. 33 No. 4 (2021): Vol 33 Issue 4

Abstract

Mixed ligand metal complexes of azo quinoline and thiosemicarbazone with Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) metal ions were synthesized. The structure and possible geometry of all the metal(II) complexes were analyzed and supported by IR, mass spectrum, elemental analysis, TG-DTA, electronic spectra (UV), magnetic susceptibility and molar conductance. The synthesized compounds were studied for their antibacterial, antifungal and antimalarial activities. The antimicrobial activity was carried out against bacteria (two Gram-positive bacteria and two Gram-negative bacteria), three fungal strain and one malarial pathogen.

Keywords

Metal(II) complexes 8-Hydroxyquinoline Thiosemicarbazone Biological activity
Borhade, S., & Tryambake, P. (2021). Synthesis, Characterization, Antibacterial, Antifungal and Antimalarial Study of Mixed Ligand Metal Complexes Derived from Azo Quinoline with Thiosemicarbazone. Asian Journal of Chemistry, 33(4), 885–891. https://doi.org/10.14233/ajchem.2021.23110
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