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Vol. 27 No. 10 (2015): Vol 27 Issue 10

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Synthesis, Characterization and Electrochemical Studies on the Interaction Mechanism of Ternary La(III) Complex with DNA

https://doi.org/10.14233/ajchem.2015.18838
Haifeng Zhao
College of Marine Life Sciences, Ocean University of China, Qingdao 266003, P.R. China
Yuhua Fan
Key Labaoratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, P.R. China
Dongmei Zhang
Key Labaoratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, P.R. China
Xin Li
Key Labaoratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, P.R. China
Feng Guo
Key Labaoratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, P.R. China
Caifeng Bi
Key Labaoratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, P.R. China

Corresponding Author(s) : Caifeng Bi

bicaifeng301@163.com

Asian Journal of Chemistry, Vol. 27 No. 10 (2015): Vol 27 Issue 10

Abstract

A new Schiff base ligand (KGOV) was synthesized using potassium salt of glycine and o-vanillin. A ternary complex of lanthanum(III) with this ligand and 1,10-phenanthroline, [La(GOV)(phen)(NO3)](NO3)·3H2O was synthesized and characterized by elemental analysis, IR, TG-DTG, 1H NMR spectra and molar conductance. The fundamental electrochemical characteristics of the La(III) ternary complex have been studied and the interactivity of La(III) complex with DNA was also studied by cyclic voltammetry. The results suggest that the complex combined with DNA in the form of intercalative binding. The binding ratio between the La(III) ternary complex and DNA was calculated to be 1:1 and the binding constant was 1.13 × 105 L mol-1.

Keywords

Schiff base La(III) complex Cyclic voltammetry DNA
Zhao, H., Fan, Y., Zhang, D., Li, X., Guo, F., & Bi, C. (2015). Synthesis, Characterization and Electrochemical Studies on the Interaction Mechanism of Ternary La(III) Complex with DNA. Asian Journal of Chemistry, 27(10), 3567–3570. https://doi.org/10.14233/ajchem.2015.18838
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