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Vol. 27 No. 10 (2015): Vol 27 Issue 10

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Synthesis, Antioxidant and Antimicrobial Activity of 4-Aminophenol and 2-Aminobenzoic Acid Based Novel Azo Compounds

https://doi.org/10.14233/ajchem.2015.18816
Shahzad Murtaza
Department of Chemistry, University of Gujrat, Gujrat-50700, Pakistan
Jamshaid Ashraf
Department of Chemistry, University of Gujrat, Gujrat-50700, Pakistan

Corresponding Author(s) : Shahzad Murtaza

shahzad.murtaza@uog.edu.pk

Asian Journal of Chemistry, Vol. 27 No. 10 (2015): Vol 27 Issue 10

Abstract

In present work, 4-aminophenol and 2-aminobenzoic acid were diazotized at low temperature and novel azo compounds from 2-aminobenzoic acid, benzamide, 4-aminophenazone, 2-bromonitrobenzene and 4-dichlorobenzene were synthesized. The resulting compounds were characterized by m.p., UV-visible and FTIR spectroscopic technique. The synthesized compounds were screened for their antibacterial activity by using disc diffusion method. The bacterial strains Escherichia coli, Shigella sonnei, Streptococcus pyrogenes, Staphylococcus aureus and Neisseria gonorrhoea were used. The antioxidant activity was also performed by using DPPH method. Results revealed that azo compounds of 4-aminophenol with 2-aminobenzoic acid and 4-aminophenazone showed much better antibacterial activity against all strains while same azo compounds had good antioxidant activity.

Keywords

4-Aminophenol 2-Aminobenzoic acid Azo compounds Antibacterial and antioxidant activities
Murtaza, S., & Ashraf, J. (2015). Synthesis, Antioxidant and Antimicrobial Activity of 4-Aminophenol and 2-Aminobenzoic Acid Based Novel Azo Compounds. Asian Journal of Chemistry, 27(10), 3551–3554. https://doi.org/10.14233/ajchem.2015.18816
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