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Vol. 37 No. 2 (2025): Vol 37 Issue 2, 2025

Copyright (c) 2025 Panaganti Leelavathi Panaganti

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Synthesis of Chromeno/Pyrano-quinolines via Tandem Approach involving Michael Addition-Cyclization Catalyzed by L-Proline/Cu(II)

https://doi.org/10.14233/ajchem.2025.33209
Md. Khaja Arif
Department of Chemistry, M.V.S. Government Arts & Science College, Mahabubnagar-509001, India
https://orcid.org/0000-0002-6539-9505
Praveen Kumar Rathod
Department of Chemistry, Osmania University, Hyderabad-500007, India
https://orcid.org/0009-0001-7027-2971
Panaganti Leelavathi
Department of Chemistry, Osmania University, Hyderabad-500007, India
https://orcid.org/0000-0002-1486-1528

Corresponding Author(s) : Panaganti Leelavathi

leelaou@gmail.com

Asian Journal of Chemistry, Vol. 37 No. 2 (2025): Vol 37 Issue 2, 2025

Abstract

In this study, the reaction of β-nitrovinylquinolines with 1,3-dicarbonyl compounds to furnish chromeno-quinolines under L-proline/Cu(II) catalysis was described. The nitro methyl derivatives of chromeno-quinolines were obtained via the Michael addition followed by the cyclization reaction of cyclic 1,3-dicarbonyl compounds with β-nitrovinylquinolines in a tandem approach. The reaction with open-chain 1,3-dicarbonyl compounds furnished the corresponding aci form of pyranoquinolines.

Keywords

Chromeno-quinolines Pyrano-quinolines β-Nitrovinylquinolines Tandem approach L-Proline/Cu(II) Solvent water
Arif, M. K., Rathod, P. K., & Leelavathi, P. (2025). Synthesis of Chromeno/Pyrano-quinolines via Tandem Approach involving Michael Addition-Cyclization Catalyzed by L-Proline/Cu(II). Asian Journal of Chemistry, 37(2), 473–478. https://doi.org/10.14233/ajchem.2025.33209
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