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Sterols from Echinopsis oxygona (Link) zucc. ex Pfeiff
Corresponding Author(s) : Consolacion Y. Ragasa
Asian Journal of Chemistry,
Vol. 32 No. 9 (2020): Vol 32 Issue 9, 2020
Abstract
Echinopsis oxygona (Link) zucc. ex Pfeiff, commonly known as easter lily cactus and sea urchin cactus, is grown as an ornamental plant in the Philippines. Chemical investigation of the dichloromethane extracts of E. oxygona has led to the isolation of ostreasterol (1), ostreasteryl fatty acid esters (2) and ergosterol peroxide (3) from the flowers and a mixture of β-sitosterol (4) and stigmasterol (5) in about 2:1 ratio from the stems. Compounds 3-5 were reported to exhibit anticancer properties. This is the first report on the chemical constituents of E. oxygona.
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- M.D. Cheek and N.R. Crouch, Bothalia, 45, 1953 (2015); https://doi.org/10.4102/abc.v45i1.1953
- T.A. Salt, J.E. Tocker and J.H. Adler, Phytochemistry, 26, 731 (1987); https://doi.org/10.1016/S0031-9422(00)84774-3
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- C.Y. Ragasa, J.L. Caro and C.-C. Shen, J. Appl. Pharm. Sci., 4, 7 (2014).
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- A. Russo, V. Cardile, M. Piovano, S. Caggia, C.L. Espinoza and J.A. Garbarino, Chem. Biol. Interact., 184, 352 (2010); https://doi.org/10.1016/j.cbi.2010.01.032
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- A.B. Awad, M. Chinnam, C.S. Fink and P.G. Bradford, Phytomed., 14, 747 (2007); https://doi.org/10.1016/j.phymed.2007.01.003
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- M.A. Gómez, M.D. García and M.T. Sáenz, Phytother. Res., 15, 633 (2001); https://doi.org/10.1002/ptr.837
- Y. Kasahara, K. Kumaki, S. Katagiri, K. Yasukawa, S. Yamanouchi, M. Takido, T. Akihisa and T. Tamura, Phytother. Res., 8, 327 (1994); https://doi.org/10.1002/ptr.2650080603
References
M.D. Cheek and N.R. Crouch, Bothalia, 45, 1953 (2015); https://doi.org/10.4102/abc.v45i1.1953
T.A. Salt, J.E. Tocker and J.H. Adler, Phytochemistry, 26, 731 (1987); https://doi.org/10.1016/S0031-9422(00)84774-3
P. Permeh, S. Saeidnia, A. Mashinchian-Moradi and A.R. Gohari, Nat. Prod. Res., 26, 774 (2012); https://doi.org/10.1080/14786419.2010.548812
C.Y. Ragasa, V.D. Ebajo Jr., R.G. Reyes, R. Brkljaèa and S. Urban, Der Pharm. Chem., 7, 331 (2015).
C.Y. Ragasa, G.S. Lorena, E.H. Mandia, D.D. Raga and C.-C. Shen, Am. J. Essent. Oils Nat. Prod., 1, 7 (2013).
V.A.S. Ng, E.M.G. Agoo, C.-C. Shen and C.Y. Ragasa, J. Appl. Pharm. Sci., 5(Suppl 1), 12 (2015).
C.Y. Ragasa, J.L. Caro and C.-C. Shen, J. Appl. Pharm. Sci., 4, 7 (2014).
M. Kobori, M. Yoshida, M. Ohnishi-Kameyama and H. Shinmoto, Br. J. Pharmacol., 150, 209 (2007); https://doi.org/10.1038/sj.bjp.0706972
Y.-H. Rhee, S.-J. Jeong, H.-J. Lee, H.-J. Lee, W. Koh, J.H. Jung, S.-H. Kim and K. Sung-Hoon, BMC Cancer, 12, 28 (2012); https://doi.org/10.1186/1471-2407-12-28
Y.K. Chen, Y.H. Kuo, Y. Chiang, J.M. Lo and L.Y. Sheen, J. Agric. Food Chem., 57, 5713 (2009); https://doi.org/10.1021/jf900581h
A. Russo, V. Cardile, M. Piovano, S. Caggia, C.L. Espinoza and J.A. Garbarino, Chem. Biol. Interact., 184, 352 (2010); https://doi.org/10.1016/j.cbi.2010.01.032
F. Leon, L. Brouard, F. Torres, J. Quintana, A. Rivera, F. Estévez and J. Bermejo, Chem. Biodivers., 5, 120 (2008); https://doi.org/10.1002/cbdv.200890002
X. Liu, C.Y. Wang, C.L. Shao, X.Y. Wei, B.G. Wang, L.-L. Sun, C.-J. Zheng and H.-S. Guan, Biochem. Syst. Ecol., 37, 127 (2009); https://doi.org/10.1016/j.bse.2009.01.009
Q.P. Wu, Y.Z. Xie, Z. Deng, X.M. Li, W. Yang, C.-W. Jiao, L. Fang, S.- Z. Li, H.-H. Pan, A.J. Yee, D.Y. Lee, C. Li, Z. Zhang, J. Guo and B.B. Yang, PLoS One, 7, e44579 (2012); https://doi.org/10.1371/journal.pone.0044579
A.B. Awad, M. Chinnam, C.S. Fink and P.G. Bradford, Phytomed., 14, 747 (2007); https://doi.org/10.1016/j.phymed.2007.01.003
G.K. Jayaprakasha, K.K. Mandadi, S.M. Poulose, Y. Jadegoud, G.A. Nagana Gowda and B.S. Patil, Bioorg. Med. Chem., 15, 4923 (2007); https://doi.org/10.1016/j.bmc.2007.04.044
A.A. Baskar, S. Ignacimuthu, G.M. Paulraj and K.S. Al Numair, BMC Comp. Alternat. Med., 10, 24 (2010); https://doi.org/10.1186/1472-6882-10-24
D.-O. Moon, K.-J. Lee, Y.H. Choi and G.-Y. Kim, Int. Immunopharmacol., 7, 1044 (2007); https://doi.org/10.1016/j.intimp.2007.03.010
M.A. Gómez, M.D. García and M.T. Sáenz, Phytother. Res., 15, 633 (2001); https://doi.org/10.1002/ptr.837
Y. Kasahara, K. Kumaki, S. Katagiri, K. Yasukawa, S. Yamanouchi, M. Takido, T. Akihisa and T. Tamura, Phytother. Res., 8, 327 (1994); https://doi.org/10.1002/ptr.2650080603