Copyright (c) 2020 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Evaluation of Phytochemical and Antioxidant Activity of Gomphrena celosioides Mart. Grown in Tien Giang Province, Vietnam
Corresponding Author(s) : Le Minh Bui
Asian Journal of Chemistry,
Vol. 32 No. 2 (2020): Vol 32 Issue 2
Abstract
Gomphrena celosioides Mart. is well known for its medicinal values worldwide. In this study, three extracts, viz. diethyl ether extract (DEE), ethanolic extract (EE) and aqueous extract (AE), were successively obtained from the leaves and stem of Gomphrena celosioides to determine the polyphenol and flavonoid content in this plant. A wide variety of pharmacologically active compounds such as alkaloid, flavonoid, terpenoid, saponin, tannin and polyphenol compounds were present in Gomphrena celosioides. The results of quantitative determination showed that total polyphenol content of DEE, EE and AE reached 35.35 ± 1.47, 250.17 ± 2.95 and 133.92 ± 3.17 mgGAE/g, respectively. Moreover, total flavonoid content of the DEE, EE and AE was 23.21 ± 1.87, 50.74 ± 2.32 and 27.25 ± 1.34 mgQE/g, respectively.In comparison with DEE and AE, the ethanolic extract exhibited the highest DPPH (IC50 = 13.29 ± 0.10 μg/mL) and ABTS (IC50 = 6.3 ± 0.11 μg/mL).
Keywords
Download Citation
Endnote/Zotero/Mendeley (RIS)BibTeX
- G.M. Cragg and D.J. Newman, Biochim. Biophys. Acta, 1830, 3670 (2013); https://doi.org/10.1016/j.bbagen.2013.02.008.
- Q. Tran, T. Le, M. Pham, T. Do, M. Vu, D. Nguyen, L. Bach, L. Bui and Q. Pham, Molecules, 24, 895 (2019); https://doi.org/10.3390/molecules24050895.
- N. Lemonnier, G.-B. Zhou, B. Prasher, M. Mukerji, Z. Chen, S.K. Brahmachari, D. Noble, C. Auffray and M. Sagner, Progr. Preven. Med., 2, e0011 (2017); https://doi.org/10.1097/pp9.0000000000000011.
- H. Yuan, Q. Ma, L. Ye and G. Piao, Molecules, 21, 559 (2016); https://doi.org/10.3390/molecules21050559.
- X. Zhou, S.W. Seto, D. Chang, H. Kiat, V. Razmovski-Naumovski, K. Chan and A. Bensoussan, Front. Pharmacol., 7, 201 (2016); https://doi.org/10.3389/fphar.2016.00201.
- U.M. Thatte and N.J. Gogtay, Proc. Indian Natl. Sci. Acad., 84, 267 (2018).
- H. Mai, T. Nguyen, T. Le, D. Nguyen and L. Bach, Processes, 7, 90 (2019); https://doi.org/10.3390/pr7020090.
- T. Pham, T. Nguyen, T. Thi, T.-T. Nguyen, T. Le, D. Vo, D. Nguyen, C. Nguyen, D. Nguyen, T. Nguyen and L. Bach, Polymers, 11, 177 (2019); https://doi.org/10.3390/polym11010177.
- N. Nguyen, N. Nguyen, N. Tran, P. Le, T. Nguyen, N. Nguyen, L. Bach, V. Doan, H. Tran, V. Le and N. Tran, Molecules, 23, 3347 (2018); https://doi.org/10.3390/molecules23123347.
- O.O. Dosumu, P.A. Idowu, P.A. Onocha and O. Ekundayo, EXCLI J., 9, 173 (2010).
- P.C. de Paula Vasconcelos, D.R. Spessotto, J.V. Marinho, M.J. Salvador, A.G. Junior and C.A.L. Kassuya, J. Ethnopharmacol., 202, 85 (2017); https://doi.org/10.1016/j.jep.2017.03.007.
- M. Yasir, B. Sultana and M. Amicucci, J. Funct. Foods, 26, 645 (2016); https://doi.org/10.1016/j.jff.2016.08.029.
- Y.Z. Cai, M. Sun and H. Corke, Trends Food Sci. Technol., 16, 370 (2005); https://doi.org/10.1016/j.tifs.2005.03.020.
- O.O. Dosumu, M. Ali, P.A. Onocha and O. Ekundayo, Iran. J. Pharm. Res., 13, 143 (2014).
- G.M. Oladele, M.O. Abatan, J.O. Olukunle and B.S. Okediran, Nat. Sci. Eng. Technol., 8, 1 (2009).
- N. Sharma, P. Sharma and R. Vijayvergia, J. Pharm. Res., 5, 4713 (2012).
- R.M.X. Moura, P.S. Pereira, A.H. Januário, S.C. França and D.A. Dias, Chem. Pharm. Bull., 52, 1342 (2004); https://doi.org/10.1248/cpb.52.1342.
- M.C. Gessler, M.H. Nkunya, L.B. Mwasumbi, M. Heinrich and M. Tanner, Acta Trop., 56, 65 (1994); https://doi.org/10.1016/0001-706X(94)90041-8.
- B.N. Dhawan, G.K. Patnaik, R.P. Rastogi, K.K. Singh and J.S. Tandon, Indian J. Exp. Biol., 15, 208 (1977).
- H. Shimoda, J. Tanaka, M. Kikuchi, T. Fukuda, H. Ito, T. Hatano and T. Yoshida, J. Agric. Food Chem., 56, 4444 (2008); https://doi.org/10.1021/jf8002174.
- L. Bhoopat, S. Srichairatanakool, D. Kanjanapothi, T. Taesotikul, H. Thananchai and T. Bhoopat, J. Ethnopharmacol., 136, 55 (2011); https://doi.org/10.1016/j.jep.2011.03.061.
- B. Halliwell, J.M.C. Gutteridge and C.E. Cross, J. Lab. Clin. Med., 119, 598 (1992).
- R. Rani, S. Arora, J. Kaur and R.K. Manhas, BMC Complement. Altern. Med., 18, 82 (2018); https://doi.org/10.1186/s12906-018-2154-4.
- O. Kadiri, Int. J. Food Prop., 20S1, S798 (2017); https://doi.org/10.1080/10942912.2017.1315130.
- D. de Beer, E. Joubert, W.C.A. Gelderblom and M. Manley, S. Afr. J. Enol. Vitic., 23, 48 (2002); https://doi.org/10.21548/23-2-2155.
- S. Chandra, S. Khan, B. Avula, H. Lata, M.H. Yang, M.A. El-Sohly and I.A. Khan, Evid. Based Complement Alternat. Med., 2014, article ID 253875 (2014); https://doi.org/10.1155/2014/253875.
- M. Mahboubi, N. Kazempour and A.R. Boland Nazar, Jundishapur J. Nat. Pharm. Prod., 8, 15 (2013); https://doi.org/10.17795/jjnpp-7621.
- G.A. Ayoola, H. Coker, S.A. Adesegun, A.A. Adepoju-Bello, K. Obaweya and E.C. Ezennia, Trop. J. Pharm. Res., 7, 1019 (2008).
- G.N. Anyasor, K.O. Ogunwenmo, O.A. Oyelana and B.E. Akpofunure, Afr. J. Biotechnol., 9, 4880 (2010).
- A. Rebaya, S.I. Belghith, B. Baghdikian, V.M. Leddet, F. Mabrouki, E. Olivier, J.K. Cherif and M.T. Ayadi, J. Appl. Pharm. Sci., 5, 52 (2015).
References
G.M. Cragg and D.J. Newman, Biochim. Biophys. Acta, 1830, 3670 (2013); https://doi.org/10.1016/j.bbagen.2013.02.008.
Q. Tran, T. Le, M. Pham, T. Do, M. Vu, D. Nguyen, L. Bach, L. Bui and Q. Pham, Molecules, 24, 895 (2019); https://doi.org/10.3390/molecules24050895.
N. Lemonnier, G.-B. Zhou, B. Prasher, M. Mukerji, Z. Chen, S.K. Brahmachari, D. Noble, C. Auffray and M. Sagner, Progr. Preven. Med., 2, e0011 (2017); https://doi.org/10.1097/pp9.0000000000000011.
H. Yuan, Q. Ma, L. Ye and G. Piao, Molecules, 21, 559 (2016); https://doi.org/10.3390/molecules21050559.
X. Zhou, S.W. Seto, D. Chang, H. Kiat, V. Razmovski-Naumovski, K. Chan and A. Bensoussan, Front. Pharmacol., 7, 201 (2016); https://doi.org/10.3389/fphar.2016.00201.
U.M. Thatte and N.J. Gogtay, Proc. Indian Natl. Sci. Acad., 84, 267 (2018).
H. Mai, T. Nguyen, T. Le, D. Nguyen and L. Bach, Processes, 7, 90 (2019); https://doi.org/10.3390/pr7020090.
T. Pham, T. Nguyen, T. Thi, T.-T. Nguyen, T. Le, D. Vo, D. Nguyen, C. Nguyen, D. Nguyen, T. Nguyen and L. Bach, Polymers, 11, 177 (2019); https://doi.org/10.3390/polym11010177.
N. Nguyen, N. Nguyen, N. Tran, P. Le, T. Nguyen, N. Nguyen, L. Bach, V. Doan, H. Tran, V. Le and N. Tran, Molecules, 23, 3347 (2018); https://doi.org/10.3390/molecules23123347.
O.O. Dosumu, P.A. Idowu, P.A. Onocha and O. Ekundayo, EXCLI J., 9, 173 (2010).
P.C. de Paula Vasconcelos, D.R. Spessotto, J.V. Marinho, M.J. Salvador, A.G. Junior and C.A.L. Kassuya, J. Ethnopharmacol., 202, 85 (2017); https://doi.org/10.1016/j.jep.2017.03.007.
M. Yasir, B. Sultana and M. Amicucci, J. Funct. Foods, 26, 645 (2016); https://doi.org/10.1016/j.jff.2016.08.029.
Y.Z. Cai, M. Sun and H. Corke, Trends Food Sci. Technol., 16, 370 (2005); https://doi.org/10.1016/j.tifs.2005.03.020.
O.O. Dosumu, M. Ali, P.A. Onocha and O. Ekundayo, Iran. J. Pharm. Res., 13, 143 (2014).
G.M. Oladele, M.O. Abatan, J.O. Olukunle and B.S. Okediran, Nat. Sci. Eng. Technol., 8, 1 (2009).
N. Sharma, P. Sharma and R. Vijayvergia, J. Pharm. Res., 5, 4713 (2012).
R.M.X. Moura, P.S. Pereira, A.H. Januário, S.C. França and D.A. Dias, Chem. Pharm. Bull., 52, 1342 (2004); https://doi.org/10.1248/cpb.52.1342.
M.C. Gessler, M.H. Nkunya, L.B. Mwasumbi, M. Heinrich and M. Tanner, Acta Trop., 56, 65 (1994); https://doi.org/10.1016/0001-706X(94)90041-8.
B.N. Dhawan, G.K. Patnaik, R.P. Rastogi, K.K. Singh and J.S. Tandon, Indian J. Exp. Biol., 15, 208 (1977).
H. Shimoda, J. Tanaka, M. Kikuchi, T. Fukuda, H. Ito, T. Hatano and T. Yoshida, J. Agric. Food Chem., 56, 4444 (2008); https://doi.org/10.1021/jf8002174.
L. Bhoopat, S. Srichairatanakool, D. Kanjanapothi, T. Taesotikul, H. Thananchai and T. Bhoopat, J. Ethnopharmacol., 136, 55 (2011); https://doi.org/10.1016/j.jep.2011.03.061.
B. Halliwell, J.M.C. Gutteridge and C.E. Cross, J. Lab. Clin. Med., 119, 598 (1992).
R. Rani, S. Arora, J. Kaur and R.K. Manhas, BMC Complement. Altern. Med., 18, 82 (2018); https://doi.org/10.1186/s12906-018-2154-4.
O. Kadiri, Int. J. Food Prop., 20S1, S798 (2017); https://doi.org/10.1080/10942912.2017.1315130.
D. de Beer, E. Joubert, W.C.A. Gelderblom and M. Manley, S. Afr. J. Enol. Vitic., 23, 48 (2002); https://doi.org/10.21548/23-2-2155.
S. Chandra, S. Khan, B. Avula, H. Lata, M.H. Yang, M.A. El-Sohly and I.A. Khan, Evid. Based Complement Alternat. Med., 2014, article ID 253875 (2014); https://doi.org/10.1155/2014/253875.
M. Mahboubi, N. Kazempour and A.R. Boland Nazar, Jundishapur J. Nat. Pharm. Prod., 8, 15 (2013); https://doi.org/10.17795/jjnpp-7621.
G.A. Ayoola, H. Coker, S.A. Adesegun, A.A. Adepoju-Bello, K. Obaweya and E.C. Ezennia, Trop. J. Pharm. Res., 7, 1019 (2008).
G.N. Anyasor, K.O. Ogunwenmo, O.A. Oyelana and B.E. Akpofunure, Afr. J. Biotechnol., 9, 4880 (2010).
A. Rebaya, S.I. Belghith, B. Baghdikian, V.M. Leddet, F. Mabrouki, E. Olivier, J.K. Cherif and M.T. Ayadi, J. Appl. Pharm. Sci., 5, 52 (2015).