Copyright (c) 2020 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Microwave Assisted Synthesis of Titanium(IV) Doped Hydroxyapatite and its Antibacterial Activities
Corresponding Author(s) : P. Sakthivel
Asian Journal of Chemistry,
Vol. 32 No. 2 (2020): Vol 32 Issue 2
Abstract
A rapid, efficient and cost-effective method for the synthesis of titanium(IV) doped hydroxyapatite using microwave assisted wet chemical method is reported. The synthesized hydroxyapatite and titanium(IV) doped hydroxyapatite (THA) samples were characterized by using XRD, FTIR and HR-TEM with EDAX. The antibacterial activity against Staphylococcus aureus and Escherichia coli was investigated by using the disc diffusion method showed good results. The anti-inflammatory activity by using the protein denaturation method proves to be less inflammable for in vivo applications. The hemolytic test showed that the samples are less hemolytic.
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References
W.J. Boyle, W.S. Simonet and D.L. Lacey, Nature, 423, 337 (2003); https://doi.org/10.1038/nature01658.
X. Feng, Curr. Chem. Biol., 3, 189 (2009); https://doi.org/10.2174/187231309788166398.
M. Vallet-Regi and J.M. González-Calbet, Prog. Solid State Chem., 32, 1 (2004); https://doi.org/10.1016/j.progsolidstchem.2004.07.001.
R. Murugan and S. Ramakrishna, Compost. Sci. Technol., 65, 2385 (2005).
Q.L. Feng, T.N. Kim, J. Wu, E.S. Park, J.O. Kim, D.Y. Lim and F.Z. Cui, Thin Solid Films, 335, 214 (1998); https://doi.org/10.1016/S0040-6090(98)00956-0.
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N. Iqbal, M.R. Abdul Kadir, N.A.N. Nik Malek, N. Humaimi Mahmood, M. Raman Murali and T. Kamarul, Mater. Lett., 89, 118 (2012); https://doi.org/10.1016/j.matlet.2012.08.057.
K. Kandori, M. Oketani, Y. Sakita and M. Wakamura, J. Mol. Catal. Chem., 360, 54 (2012); https://doi.org/10.1016/j.molcata.2012.04.009.
K. Kandori, M. Oketani and M. Wakamura, Colloids Surf. B Biointerf., 102, 908 (2013); https://doi.org/10.1016/j.colsurfb.2012.09.022.
M.R. Saeri, A. Afshar, M. Ghorbani, N. Ehsani and C.C. Sorrell, Mater. Lett., 57, 4064 (2003); https://doi.org/10.1016/S0167-577X(03)00266-0.
C.M. Mardziah, I. Sopyan and S. Ramesh, Artif. Organs, 23, 105 (2009).
V. Sarath Chandra, G. Baskar, R.V. uganthi, K. Elayaraja, M.I. Ahymah Joshy, W. Sofi Beaula, R. Mythili, G. Venkatraman and S. Narayana Kalkura, ACS Appl. Mater. Interfaces, 4, 1200 (2012); https://doi.org/10.1021/am300140q.
W. Pon-On, S. Meejoo and M. Tang, Int. J. Nanosci., 6, 9 (2007); https://doi.org/10.1142/S0219581X07004262.
O.A. Awoyinka, I.O. Balogun and A.A. Ogunnowo, J. Med. Plants Res., 1, 63 (2007).
N.I. Osman, N.J. Sidik, A. Awal, N.A.M. Adam and N.I. Rezali, J. Intercult. Ethnopharmacol., 5, 343 (2016); https://doi.org/10.5455/jice.20160731025522.
Z.-G. Yang, H.-X. Sun and W.-H. Fang, Vaccine, 23, 5196 (2005); https://doi.org/10.1016/j.vaccine.2005.06.016.
K. Arul, E. Kolanthai, E. Manikandan, G.M. Bhalerao, V.S. Chandra, J.R. Ramya, U.K. Mudali, K.G.M. Nair and S.N. Kalkura, Mater. Res. Bull., 67, 55 (2015); https://doi.org/10.1016/j.materresbull.2015.02.054.
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A.R. Boyd, L. Rutledge, L.D. Randolph and B.J. Meenan, Mater. Sci. Eng. C, 46, 290 (2015); https://doi.org/10.1016/j.msec.2014.10.046.
B. Tian, W. Chen, Y. Dong, J.V. Marymont, Y. Lei, Q. Ke, Y. Guo and Z. Zhu, RSC Adv., 6, 8549 (2016); https://doi.org/10.1039/C5RA25391H.
P. Wang, C. Li, H. Gong, X. Jiang, H. Wang and K. Li, Powder Technol., 203, 315 (2010); https://doi.org/10.1016/j.powtec.2010.05.023.
N. Specchia, A. Pagnotta, M. Cappella, A. Tampieri and F. Greco, J. Mater. Sci., 37, 577 (2002); https://doi.org/10.1023/A:1013725809480.
B. Singh, A.K. Dubey, S. Kumar, N. Saha, B. Basu and R. Gupta, Mater. Sci. Eng. C, 31, 1320 (2011); https://doi.org/10.1016/j.msec.2011.04.015.
L. Argueta-Figueroa, R.A. Morales-Luckie, R.J. Scougall-Vilchis and O.F. Olea-Mejía, Progr. Nat. Sci.: Materi. Int., 24, 321 (2014); https://doi.org/10.1016/j.pnsc.2014.07.002.
C.P. Dhanalakshmi, L. Vijayalakshmi and V. Narayanan, Asian J. Chem., 24, 5497 (2012).
V. Stanic, D. Janackovic, S. Dimitrijevic, S.B. Tanaskovic, M. Mitric, M.S. Pavlovic, A. Krstic, D. Jovanovic and S. Raièevic, Appl. Surf. Sci., 257, 4510 (2011); https://doi.org/10.1016/j.apsusc.2010.12.113.
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