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Vol. 32 No. 12 (2020): Vol 32 Issue 12, 2020

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High Diffusivity Coefficient of Cyclic Voltammetric Behaviour of Semicarbazones and Thiosemicarbazones and their Antimicrobial Studies

https://doi.org/10.14233/ajchem.2020.22521
J.B. Veeramalini
Department of Chemical Engineering, School of Bio and Chemical Engineering, Kalasalingam Academy of Research and Education, Krishnankoil-626138, India
B.A. Brundha
Department of Chemistry, VelTech HighTech Dr. Rangarajan Dr. Sakunthala Engineering College, Chennai-600062, India
S. Gowthami
Department of Chemical Engineering, VelTech HighTech Dr. Rangarajan Dr. Sakunthala Engineering College, Avadi, Chennai-600062, India
G. Baskar
Department of Applied Chemistry, Sri Venkateswara College of Engineering, Sriperumbudur-602105, India

Corresponding Author(s) : J.B. Veeramalini

veeramalini@gmail.com

Asian Journal of Chemistry, Vol. 32 No. 12 (2020): Vol 32 Issue 12, 2020

Abstract

In this work, a series of N-hydroxy-2,6-diaryl-3-alkylpiperidin-4-one semicarbazones and thiosemicarbazones have been synthesized and also subjected towards cyclic voltammetric studies. The structure of reduced products was confirmed by FTIR, 1H & 13C NMR spectral analysis. Further products were also screened for antimicrobial activities and it shows high significant effect towards Aspergillus niger among the eight tested fungal species. The propency towards order of reduced products is observed sharply and it was established that irreversible reduction of two electron transfers has taken for all four synthesized compounds and highly pH dependent. Among the synthesized compound, thiosemicarbzones showed versatile features with high diffusion coefficient value in minimum power consumption of current function.

Keywords

N-Hydroxypiperdone Semicarbazones Thiosemicarbazones Cyclic voltammetry Diffusivity coefficient
Veeramalini, J., Brundha, B., Gowthami, S., & Baskar, G. (2020). High Diffusivity Coefficient of Cyclic Voltammetric Behaviour of Semicarbazones and Thiosemicarbazones and their Antimicrobial Studies. Asian Journal of Chemistry, 32(12), 3186–3190. https://doi.org/10.14233/ajchem.2020.22521
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