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Vol. 32 No. 10 (2020): Vol 32 Issue 10

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Isolation, Semi-Synthesis and Antifeedant Activity of Constituents from Derris scandens Benth.

https://doi.org/10.14233/ajchem.2020.22801
P. Poorna
Divi’s Laboratories Limited, Unit-2, Chippada, Visakhapatnam-531162, India ; Department of Chemistry, Institute of Science, GITAM University, Rushikonda, Visakhapatnam-530045, India
K. Ramakrishna
Department of Chemistry, Institute of Science, GITAM University, Rushikonda, Visakhapatnam-530045, India
M. Suri Appa Rao
Divi’s Laboratories Limited, Unit-2, Chippada, Visakhapatnam-531162, India

Corresponding Author(s) : K. Ramakrishna

rkariped@gitam.edu

Asian Journal of Chemistry, Vol. 32 No. 10 (2020): Vol 32 Issue 10

Abstract

This work describes the semi-synthesis of derivatives from derris isoflavone-A (1), scandenin (2) and 6,8-diprenyl-4′,5,7-trihydroxy isoflavone (3) which are major constituents isolated from chloroform extract of Derris scandens Benth. All the semi-synthesized derivatives (4-11) were characterized by NMR and mass spectroscopic techniques. All these derivatives are evaluated for their antifeedant activity in castor semilooper and tobacco caterpillar using a no-choice laboratory bioassay. The results demonstrated that scandenin (2), compounds 5, 7 and 10 have shown potent insecticidal activity.

Keywords

Derris scandens Benth. Scandenin Antifeedant activity
Poorna, P., Ramakrishna, K., & Suri Appa Rao, M. (2020). Isolation, Semi-Synthesis and Antifeedant Activity of Constituents from Derris scandens Benth. Asian Journal of Chemistry, 32(10), 2535–2540. https://doi.org/10.14233/ajchem.2020.22801
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