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Vol. 36 No. 6 (2024): Vol 36 Issue 6, 2024

Copyright (c) 2024 Netra Pal Singh, Maitreyi Singh, Anand Ratnam, Anuroop Kumar

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Carboxamide-based Fluorescent Sensor for the Detection of Mg2+ and Ni2+ Ions

https://doi.org/10.14233/ajchem.2024.31405
Netra Pal Singh
Department of Chemistry, D.D.U. Gorakhpur University, Gorakhpur-273009, India; Present address: Department of Chemistry, Dr. H.S. Gour Vishwavidyalaya (A Central University), Sagar-470003, India
https://orcid.org/0000-0002-0542-0472
Maitreyi Singh
Department of Chemistry, D.D.U. Gorakhpur University, Gorakhpur-273009, India
https://orcid.org/0009-0009-4156-0649
Anand Ratnam
Department of Chemistry, D.D.U. Gorakhpur University, Gorakhpur-273009, India
https://orcid.org/0000-0002-4152-3815
Anuroop Kumar
Department of Chemistry, Meerut College, Meerut-250003, India
https://orcid.org/0000-0001-6870-2998

Corresponding Author(s) : Netra Pal Singh

npsmcm.in@gmail.com

Asian Journal of Chemistry, Vol. 36 No. 6 (2024): Vol 36 Issue 6, 2024

Abstract

In this work, pyridine-2,6-dicarboxamide based ligand was synthesized by reacting pyridine-2,6-dicarboxylic acid with a thiazole derivative. The synthesized ligand was characterized by 1H NMR and 13C NMR, IR spectroscopic and mass spectrometry. The UV-visible spectrum accompanied with fluorescent spectral studies, binding constants and limit of detection proved efficient sensing abilities. The ligand was found to bind with one equivalent of an M2+ ion as validated by Job’s plot and binding parameters. The novel fluorescent probe based on amide ligand exhibits precise and selective response to Mg2+ and Ni2+ ions in HEPES buffer solution showing the detection limit to be 2.1502 × 10–8 mol/L and 4.8007 × 10–8 mol/L, respectively. The binding stoichiometry of amide ligand with Mg2+ and Ni2+ was estimated by Job’s plot method and found to be 1:1, which is further confirmed by mass spectrometry.

Keywords

Fluorescence quenching Chemosensor Binding constant Metal ions detection Mg2+ and Ni2+
Singh, N. P., Singh, M., Ratnam, A., & Kumar, A. (2024). Carboxamide-based Fluorescent Sensor for the Detection of Mg2+ and Ni2+ Ions. Asian Journal of Chemistry, 36(6), 1371–1376. https://doi.org/10.14233/ajchem.2024.31405
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References
  1. K.P. Carter, A.M. Young and A.E. Palmer, Chem. Rev., 114, 4564 (2014); https://doi.org/10.1021/cr400546e
  2. J. Lian, Q. Xu, Y. Wang and F. Meng, Front. Chem., 8, 593291 (2020); https://doi.org/10.3389/fchem.2020.593291
  3. Y. Shi, W. Zhang, Y. Xue and J. Zhang, Chemosensors, 11, 226 (2023); https://doi.org/10.3390/chemosensors11040226
  4. D. Bansal and R. Gupta, Dalton Trans., 45, 502 (2016); https://doi.org/10.1039/C5DT03669K
  5. P. Kumar, V. Kumar and R. Gupta, RSC Adv., 5, 97874 (2015); https://doi.org/10.1039/C5RA20760F
  6. P. Kumar, V. Kumar and R. Gupta, RSC Adv., 7, 7734 (2017); https://doi.org/10.1039/C6RA27565F
  7. V. Kumar, P. Kumar and R. Gupta, RSC Adv., 7, 23127 (2017); https://doi.org/10.1039/C7RA01453H
  8. P. Kumar, V. Kumar and R. Gupta, Dalton Trans., 46, 10205 (2017); https://doi.org/10.1039/C7DT01811H
  9. P. Kumar, V. Kumar, S. Pandey and R. Gupta, Dalton Trans., 47, 9536 (2018); https://doi.org/10.1039/C8DT01351A
  10. H. Rubin, BioEssays, 27, 311 (2005); https://doi.org/10.1002/bies.20183
  11. A.A. Mushegian, Sci. Signal., 9, ec269 (2016); https://doi.org/10.1126/scisignal.aal3828
  12. M.H. Pontes, J. Yeom and E.A. Groisman, Mol. Cell, 64, 480 (2016); https://doi.org/10.1016/j.molcel.2016.05.008
  13. B. O’Rourke, P.H. Backx and E. Marban, Science, 257, 245 (1992); https://doi.org/10.1126/science.1321495
  14. F. Wolf, Mol. Aspects Med., 24, 3 (2003); https://doi.org/10.1016/S0098-2997(02)00087-0
  15. W. Jahnen-Dechent and M. Ketteler, Clin. Kidney J., 5(Suppl 1), i3 (2012); https://doi.org/10.1093/ndtplus/sfr163
  16. J. Kim, T. Morozumi and H. Nakamura, Org. Lett., 9, 4419 (2007); https://doi.org/10.1021/ol701976x
  17. G. Men, C. Chen, S. Zhang, C. Liang, Y. Wang, M. Deng, H. Shang, B. Yang and S. Jiang, Dalton Trans., 44, 2755 (2015); https://doi.org/10.1039/C4DT03068K
  18. Y. Wang, Z.-G. Wang, X.-Q. Song, Q. Chen, H. Tian, C.-Z. Xie, Q.-Z. Li and J.-Y. Xu, Analyst, 144, 4024 (2019); https://doi.org/10.1039/C9AN00583H
  19. S.B. Mulrooney and R.P. Hausinger, Microbiol. Rev., 27, 239 (2003); https://doi.org/10.1016/S0168-6445(03)00042-1
  20. S.W. Ragsdale, J. Biol. Chem., 284, 18571 (2009); https://doi.org/10.1074/jbc.R900020200
  21. R.J. Maier, Biochem. Soc. Trans., 33, 83 (2005); https://doi.org/10.1042/BST0330083
  22. K.S. Kasprzak, F.W. Sunderman and K. Salnikowa, Mutat. Res., 533, 67 (2003); https://doi.org/10.1016/j.mrfmmm.2003.08.021
  23. P.H. Kuck, Mineral Commodity Summaries: Nickel, United States Geological Survey (2006).
  24. X.Q. Liu, X. Zhou, X. Shu and J. Zhu, Macromolecules, 42, 7634 (2009); https://doi.org/10.1021/ma901879t
  25. J.R. Sheng, F. Feng, Y. Qiang, F.G. Liang, L. Sen and F.-H. Wei, Anal. Lett., 41, 2203 (2008); https://doi.org/10.1080/00032710802237673
  26. H.X. Wang, D.L. Wang, Q. Wang, X. Li and C.A. Schalley, Org. Biomol. Chem., 8, 1017 (2010); https://doi.org/10.1039/b921342b
  27. B. Qin, X. Zhang and J. Zhang, Cryst. Growth Des., 20, 5120 (2020); https://doi.org/10.1021/acs.cgd.0c00308
  28. M. Shamsipur, T. Poursaberi, A.R. Karami, M. Hosseini, A. Momeni, N. Alizadeh, M. Yousefi and M.R. Ganjali, Anal. Chim. Acta, 501, 55 (2004); https://doi.org/10.1016/j.aca.2003.09.008
  29. V.K. Gupta, R.N. Goyal, S. Agarwal, P. Kumar and N. Bachheti, Talanta, 71, 795 (2007); https://doi.org/10.1016/j.talanta.2006.05.036
  30. I. Grabchev, J.M. Chovelon and X. Qian, New J. Chem., 27, 337 (2003); https://doi.org/10.1039/b204727f
  31. I. Qureshi, M.A. Qazi and S. Memon, Sens. Actuators B Chem., 141, 45 (2009); https://doi.org/10.1016/j.snb.2009.06.010
  32. H. Li, S.J. Zhang, C.L. Gong, Y.-F. Li, Y. Liang, Z.-G. Qi and S. Chen, Analyst, 138, 7090 (2013); https://doi.org/10.1039/c3an01162c
  33. S. Goswami, S. Chakraborty, S. Paul, S. Halder and A.C. Maity, Tetrahedron Lett., 54, 5075 (2013); https://doi.org/10.1016/j.tetlet.2013.07.051
  34. L. Lin, S. Hu, Y. Yan, D.-J. Wang, L. Fan, Y.-J. Hu and G.-D. Yin, Res. Chem. Intermed., 43, 283 (2017); https://doi.org/10.1007/s11164-016-2621-9
  35. S. Atilgan, T. Ozdemir and E.U. Akkaya, Org. Lett., 10, 4065 (2008); https://doi.org/10.1021/ol801554t
  36. P. Teolato, E. Rampazzo, M. Arduini, F. Mancin, P. Tecilla and U. Tonellato, Chem. Eur. J., 13, 2238 (2007); https://doi.org/10.1002/chem.200600624
  37. H.J. Kim, J. Hong, A. Hong, S. Ham, J.H. Lee and S.J. Kim, Org. Lett., 10, 1963 (2008); https://doi.org/10.1021/ol800475d
  38. R. Martinez, F. Zapata, A. Caballero, A. Espinosa, A. Tarraga and P. Molina, Org. Lett., 8, 3235 (2006); https://doi.org/10.1021/ol0610791
  39. N.C. Lim, S.V. Pavlova and C. Bruckner, Inorg. Chem., 48, 1173 (2009); https://doi.org/10.1021/ic801322x
  40. J.L. Bricks, A. Kovalchuk, C. Trieflinger, M. Nofz, M. Buschel, A.I. Tolmachev, J. Daub and K.J.J. Rurack, J. Am. Chem. Soc., 127, 13522 (2005); https://doi.org/10.1021/ja050652t
  41. C. Liang, W. Bu, C. Li, G. Men, M. Deng, Y. Jiangyao, H. Sun and S. Jiang, Dalton Trans., 44, 11352 (2015); https://doi.org/10.1039/C5DT00689A
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