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Vol. 31 No. 9 (2019): Vol 31 Issue 9

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Synthesis, Characterization and Antimicrobial Evaluation of Cobalt(III) Complexes of 4-(2-Substituted Phenylimino)-2-(4-Substituted Phenyl)-4H-chromen-3-ol

https://doi.org/10.14233/ajchem.2019.22068
Ashok K. Singh
Department of Chemistry, University of Lucknow, Lucknow-226007, India
Suresh K. Patel
Department of Chemistry, University of Lucknow, Lucknow-226007, India
https://orcid.org/0000-0001-9173-6491
Asif Jafri
Department of Zoology, University of Lucknow, Lucknow-226007, India

Corresponding Author(s) : Ashok K. Singh

singhaks3@rediffmail.com

Asian Journal of Chemistry, Vol. 31 No. 9 (2019): Vol 31 Issue 9

Abstract

A series of eight Co(III) complexes [CoL1-8(H2O)2Cl] (I-1 to I-8) incorporating 4-(2-substituted phenylimino)-2-(4-substituted phenyl)-4H-chromen-3-ol, as a tridentate imino flavone ligands (L1 to L8, 2-sub. = NH2, SH, 4-sub. = OMe, OH, Cl, NMe2) have been synthesized, characterized and the geometry of the complexes were optimized by DFT. The chemical structure of synthesized imino flavone ligands and their complexes were characterized by elemental analysis, 1H NMR, 13C NMR, UV-visible, IR, ESI-mass spectral data, conductometric and magnetic measurements. The synthesized compounds have been screened for their in vitro antibacterial activities against bacteria Vibrio cholerae, Salmonella typhi, Staphylococcus aureus, Escherichia coli and antifungal activities against fungi Candida albicans and Aspergillus flavus by paper disc diffusion method. The complexes I-3, I-4, I-7 and I-8 showed good antimicrobial activities against pathogens.

Keywords

Iminoflavone Co(III) complexes Optimized geometry Antimicrobial activities
Singh, A. K., Patel, S. K., & Jafri, A. (2019). Synthesis, Characterization and Antimicrobial Evaluation of Cobalt(III) Complexes of 4-(2-Substituted Phenylimino)-2-(4-Substituted Phenyl)-4H-chromen-3-ol. Asian Journal of Chemistry, 31(9), 2015–2021. https://doi.org/10.14233/ajchem.2019.22068
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