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Vol. 31 No. 9 (2019): Vol 31 Issue 9

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Synthesis, Characterization and Antimicrobial Activities of Copper(II) Complexes of Schiff Base Ligand 2-[(3′-N-salicylidinephenyl)benzimidazole]

https://doi.org/10.14233/ajchem.2019.22067
B. Roopashree
Department of Chemistry, J.S.S. Academy of Technical Education, (Affiliated to Visvesvaraya Technological University), Bengaluru-560060, India
https://orcid.org/0000-0002-4485-8805
V. Gayathri
Department of Post Graduate Studies in Chemistry, Central College Campus, Bangalore University, Bengaluru-560001, India
https://orcid.org/0000-0001-6207-6463

Corresponding Author(s) : B. Roopashree

roopajss@gmail.com

Asian Journal of Chemistry, Vol. 31 No. 9 (2019): Vol 31 Issue 9

Abstract

CuX2·6H2O (X = Cl–, Br– or ClO4–) reacted with a Schiff base ligand 2-[(3′-N-salicylidinephenyl)benzimidazole] in 1:2 mole ratio in methanol to yield brown colored complexes of types [CuCl2L]2, [CuBr1.5L1.5]2Br and [Cu(OClO3)L2]2(ClO4)2·4H2O. The complexes were characterized by analytical and spectroscopic studies such as elemental analysis, conductivity and magnetic moment measurements, thermogravimetric analysis, IR, far-IR, electronic, ESR and mass spectral studies. IR spectral studies suggested the coordination of ligand to the central metal atom via tertiary nitrogen of benzimidazole and nitrogen of azomethine group. Based on these studies, binuclear structure was proposed for all the copper complexes. The ligand and its copper(II) complexes were screened for antibacterial and antifungal activities.

Keywords

Schiff base Benzimidazole Copper(II) complexes Biological activity
Roopashree, B., & Gayathri, V. (2019). Synthesis, Characterization and Antimicrobial Activities of Copper(II) Complexes of Schiff Base Ligand 2-[(3′-N-salicylidinephenyl)benzimidazole]. Asian Journal of Chemistry, 31(9), 1979–1984. https://doi.org/10.14233/ajchem.2019.22067
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References
  1. T. Sakai, T. Hamada, N. Awata and J. Watanabe, J. Pharmacobiodyn., 12, 530 (1989); https://doi.org/10.1248/bpb1978.12.530.
  2. A.A. Spasov, I.N. Yozhitsa, L.I. Bugaeva and V.A. Anisimova, Pharm. Chem. J., 33, 232 (1999); https://doi.org/10.1007/BF02510042.
  3. R.A. Bucknall and S.B. Carter, Nature, 213, 1099 (1967); https://doi.org/10.1038/2131099a0.
  4. F. Gumus, O. Algul, G. Eren, H. Eroglu, N. Diril, S. Gür and A. Özkul, Eur. J. Med. Chem., 38, 473 (2003); https://doi.org/10.1016/S0223-5234(03)00058-8.
  5. M. Gökçe, S. Utku, S. Gür, A. Özkul and F. Gümüs, Eur. J. Med. Chem., 40, 135 (2005); https://doi.org/10.1016/j.ejmech.2004.09.017.
  6. N. Bharti, M.T. Shailendra, M.T. Gonzalez Garza, D.E. Cruz-Vega, J. Castro-Garza, K. Saleem, F. Naqvi, M.R. Maurya and A. Azam, Bioorg. Med. Chem. Lett., 12, 869 (2002); https://doi.org/10.1016/S0960-894X(02)00034-3.
  7. Y. Elerman, M. Kabak and A. Elmali, Z. Natruforsch., 57, 651 (2002); https://doi.org/10.1515/znb-2002-0610.
  8. N. Chantarasiri, V. Ruangpornvisuti, N. Muangsin, T. Mananunsap, H. Detsen, C. Batiya and N. Chaichit, Spectrochim. Acta A Mol. Biomol. Spectrosc., 61, 157 (2005); https://doi.org/10.1016/j.saa.2004.03.015.
  9. N. Chantarasiri, V. Ruangpornvisuti, N. Muangsin, T. Mananunsap, H. Detsen, C. Batiya and N. Chaichit, J. Mol. Struct., 701, 93 (2004); https://doi.org/10.1016/j.molstruc.2004.05.015.
  10. A.A. Soliman and G.G. Mohamed, Thermochim. Acta, 421, 151 (2004); https://doi.org/10.1016/j.tca.2004.03.010.
  11. J. Kaizer, Z. Zsigmond, I. Ganszky, G. Speier, M. Giorgi and M. Réglier, Inorg. Chem., 46, 4660 (2007); https://doi.org/10.1021/ic062309a.
  12. E. Tas, I. Ucar, V.T. Kasumov, A. Kilic and A. Bulut, Spectrochim. Acta A Mol. Biomol. Spectrosc., 68, 463 (2007); https://doi.org/10.1016/j.saa.2006.11.052.
  13. E. Tas, V. Kasumov, O. Sahin and M. Özdemir, Transition Met. Chem., 27, 442 (2002); https://doi.org/10.1023/A:1015011517647.
  14. J. Cui and M. Zhang, J. Chem. Res., 34, 41 (2010); https://doi.org/10.3184/030823410X12628736648105.
  15. M. Ulusoy, O. Sahin, O. Büyükgüngör and B. Çetinkaya, J. Organomet. Chem., 693, 1895 (2008); https://doi.org/10.1016/j.jorganchem.2008.02.017.
  16. N. Bharti, M.R. Maurya, F. Naqvi and A. Azam, Bioorg. Med. Chem. Lett., 10, 2243 (2000); https://doi.org/10.1016/S0960-894X(00)00446-7.
  17. G. Wilkinson, Comprehensive Coordination Chemistry, Pergamon Press: Oxford, vol. 5, p. 775 (1987).
  18. K.D. Karlin and J. Zubieta, Copper Coordination Chemistry, Biochemical and Inorganic perspective, Adenine Press, Guilderland: New York (1983-1986).
  19. J. Gaazo, I.B. Bersuker, J. Garaj, M. Kabesova, H. Langfelderova, J. Kojout, M. Melnik, M. Serator and F. Valach, Coord. Chem. Rev., 19, 253 (1976); https://doi.org/10.1016/S0010-8545(00)80317-3.
  20. M. Palaniandavar, R.J. Butcher and A.W. Addison, Inorg. Chem., 35, 467 (1996); https://doi.org/10.1021/ic941396g.
  21. A. Benzekri, P. Dubourdeaux, J.M. Latour, P. Rey and J. Laugier, J. Chem. Soc., Dalton Trans., 3359 (1991); https://doi.org/10.1039/dt9910003359.
  22. J.D. Crane and D.E. Fenton, Polyhedron, 10, 1809 (1991); https://doi.org/10.1016/S0277-5387(00)83804-8.
  23. H.P. Berends and D.W. Stephan, Inorg. Chim. Acta, 99, L53 (1985); https://doi.org/10.1016/S0020-1693(00)87956-6.
  24. J.D. Crane, R. Hughes and E. Sinn, Inorg. Chim. Acta, 237, 181 (1995); https://doi.org/10.1016/0020-1693(95)04653-Q.
  25. V. Mckee, J.V. Dagdigian, R. Bau and C.A. Reed, J. Am. Chem. Soc., 103, 7000 (1981); https://doi.org/10.1021/ja00413a054.
  26. H.J. Hoorn, P. de Joode, W.L. Driessen and J. Reedijk, React. Funct. Polym., 27, 223 (1995); https://doi.org/10.1016/1381-5148(95)96870-G.
  27. P.M. van Berkel, D.J. Dijkstra, W.L. Driessen, J. Reedijk and D.C. Sherrington, React. Funct. Polym., 28, 39 (1995); https://doi.org/10.1016/1381-5148(95)00078-2.
  28. D.D. Perrin, Armarego and D.R. Perrin, Purification of Laboratory Chemicals, Pergamon Press Pvt Ltd: Oxford, edn 1 (1966).
  29. B. Roopashree, V. Gayathri and H. Mukund, J. Coord. Chem., 65, 1354 (2012); https://doi.org/10.1080/00958972.2012.673123.
  30. G.R. Suman, G. Bubbly, S.B. Gudennavar, S. Muthu, B. Roopashree, V. Gayatri and N.M. Nanje Gowda, J. Mol. Struct., 1139, 247 (2017); https://doi.org/10.1016/j.molstruc.2017.03.043.
  31. W.I. Geary, Coord. Chem. Rev., 7, 81 (1971); https://doi.org/10.1016/S0010-8545(00)80009-0.
  32. G. Mohamed, S.A. Salam, S. Oumar, U. Russo and V. Maurizio, Polyhedron, 14, 655 (1995); https://doi.org/10.1016/0277-5387(94)00295-P.
  33. G. Bombieri, E. Benetollo, A. Polo, L. De Cola, D.L. Smailes and L.M. Vallarino, Inorg. Chem., 25, 1127 (1986); https://doi.org/10.1021/ic00228a014.
  34. L. De Cola, D.L. Smailes and L.M. Vallarino, Inorg. Chem., 25, 1729 (1986); https://doi.org/10.1021/ic00230a042.
  35. M.P. Ngwenya, D. Chen, A.E. Martell and J. Reibenspies, Inorg. Chem., 30, 2732 (1991); https://doi.org/10.1021/ic00013a006.
  36. W. Coleman and L.T. Taylor, Inorg. Chem., 10, 2195 (1971); https://doi.org/10.1021/ic50104a021.
  37. K. Nakamoto, Infrared and Raman Spectra of Inorganic and Coordination Compounds, Wiley Interscience, New York, edn 4 (1986).
  38. N.M.N. Gowda, S.B. Naikar and G.K.N. Reddy, Adv. Inorg. Chem. Radiochem., 28, 255 (1984); https://doi.org/10.1016/S0898-8838(08)60210-X.
  39. A. Bax and M.F. Summers, J. Am. Chem. Soc., 108, 2093 (1986); https://doi.org/10.1021/ja00268a061.
  40. W. Willker, D. Leibfritz, R. Kerssebaum and W. Bermel, Magn. Reson. Chem., 31, 287 (1993); https://doi.org/10.1002/mrc.1260310315.
  41. A.B.P. Lever, Inorganic Electronic Spectroscopy, Elsevier: New York (1968).
  42. A. Piguet, B. Bocquet, E. Muller and A.F. Williams, Helv. Chim. Acta, 72, 323 (1989); https://doi.org/10.1002/hlca.19890720218.
  43. R.M. Silverstein, G.C. Bassler and T.C. Morril, Spectroscopic Identification of Organic Compounds, Wiley: Singapore, edn 4 (1981).
  44. R. Nagar, Inorg. Biochem., 40, 349 (1990); https://doi.org/10.1016/0162-0134(90)80069-A.
  45. Y. Anjaneyulu and R.P. Rao, Synth. React. Inorg. Met.-Org. Chem., 26, 257 (1986); https://doi.org/10.1080/00945718608057530.
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