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Vol. 31 No. 8 (2019): Vol 31 Issue 8

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Optimization of Extraction Parameters for Antioxidant and Total Phenolic Content of Ficus carica L. Latex from White Genoa Cultivar

https://doi.org/10.14233/ajchem.2019.21946
M. Shahinuzzaman
Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor 43600, Malaysia
Zahira Yaakob
Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor 43600, Malaysia
Norrakiah Abdullah Sani
Centre for Biotechnology and Functional Food, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor 43600, Malaysia
Parul Akhtar
Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor 43600, Malaysia
Md. Zahidul Islam
Department of Chemistry, Faculty of Arts and Science, Sakarya University, 54187 Sakarya, Turkey
Mst. Afsana Mimi
Department of Applied Chemistry and Chemical Engineering, Faculty of Engineering and Technology, Islamic University Kushtia, Bangladesh
Shamsul Akmal Shamsudin
Saf Fa Fig Garden, Kuala Pilah 72000, Negeri Sembilan, Malaysia

Corresponding Author(s) : M. Shahinuzzaman

shahinchmiu@gmail.com

Asian Journal of Chemistry, Vol. 31 No. 8 (2019): Vol 31 Issue 8

Abstract

In this study, the extraction parameters for antioxidant activity and total phenolic content of Ficus carica L. latex from White Genoa cultivar were optimized using response surface methodology (RSM). Effect of temperature, extraction time and solvent concentration for maceration extraction were investigated. The antioxidant activity was determined with DPPH (1,1-diphenyl-2-picrylhydrazyl) assay and expressed as percent of inhibition. Total phenolic content (TPC) was determined with Folin-Ciocalteu assay and expressed as μg GAE/mL. The optimum points that maximize the DPPH inhibition are 32 °C temperature, 31.50 min extraction time and 65 % ethanol. The optimum points for TPC are 32 °C temperature, 37.50 min extraction time and 70 % ethanol. The predicted DPPH inhibition and TPC at these predicted points are 67.08 % and 313.811 μg GAE/mL respectively. In this model, the F value (26.03 and 20.96), R-Squared value (0.9591 and 0.9497) and signal to noise ratio (13.431 and 12.799) are reasonable to fit the model.

Keywords

Ficus carica Latex Antioxidant Total phenol RSM Optimization
Shahinuzzaman, M., Yaakob, Z., Sani, N. A., Akhtar, P., Islam, M. Z., Mimi, M. A., & Shamsudin, S. A. (2019). Optimization of Extraction Parameters for Antioxidant and Total Phenolic Content of Ficus carica L. Latex from White Genoa Cultivar. Asian Journal of Chemistry, 31(8), 1859–1865. https://doi.org/10.14233/ajchem.2019.21946
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