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Antibacterial Activity of a New Flavone Glycoside from the Stems of Holmskioldia sanguinea Retz.
Corresponding Author(s) : R.N. Yadava
Asian Journal of Chemistry,
Vol. 31 No. 8 (2019): Vol 31 Issue 8
Abstract
A new flavone glycoside was isolated from ethanolic extract of stem parts of Holmskioldia sanguinea Retz. Its structure was characterized as 3,4′-dihydroxy-5,7-dimethoxyflavone-3-O-β-D-galactopyranosyl(1→4)-O-β-D-arabinopyranosyl-4′-O-α-L-rhamnopyranoside (1) by colour reactions, chemical degradation and spectroscopic analysis. Antibacterial activity of compound 1 was evaluated against various Gram positive and Gram negative bacteria showing a significant effects.
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- I.E. Oboh, J.O. Akerele and O. Obasuyi, Tropical J. Pharm. Res., 6, 809 (2007); https://doi.org/10.4314/tjpr.v6i4.3.
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- W.A. Bubb, Concepts Magn. Reson. Part A, 19A, 1 (2003); https://doi.org/10.1002/cmr.a.10080.
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- R.N. Yadava and P. Yadav, Am. J. Phytomed. Clin. Therap., 1, 672 (2013).
- J.M. Bobbitt, Adv. Carbohydrate Chem., 11, 1 (1956).
- N.P.J. Price, Appl. Biochem. Biotechnol., 148, 271 (2008); https://doi.org/10.1007/s12010-007-8044-8.
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References
R.P. Rastogi and B.N. Mehrotra, Compendium of Indian Medicinal Plants, vol. 3, CDRI Lucknow and National Institute of Science Communication, New Delhi, p. 346 (1980-1984).
L.V. Asolkar, K.K. Kakkar and O.J. Chakre, Second Supplement to – A Glossary of Indian Medicinal Plants with Active Principles Part-I (A-K), National Institute of Science Communication (CSIR), p. 357 (1965-1981).
P. Singh, S. Jain, M. Bhala, R.B. Goyal, D. Jayaprakash and N.K. Lohiya, Phytother. Res., 4, 86 (1990); https://doi.org/10.1002/ptr.2650040303.
M. Pal, M. Singh, P.K. Chaudhuri, R.P. Sharma and N. Singh, Phytother. Res., 10, 357 (1996); https://doi.org/10.1002/(SICI)1099-1573(199606)10:4<357::AIDPTR840>3.0.CO;2-L.
M. Pal, H. Joshi, V.P. Kapoor, P. Pushpangadan and L. Chaurasia, Phytother. Res., 17, 1215 (2003); https://doi.org/10.1002/ptr.1327.
P.K. Chaudhuri, R. Srivastava, S. Kumar and S. Kumar, Phytother. Res., 18, 114 (2004); https://doi.org/10.1002/ptr.1278.
M. Pal, S.K. Tewari and Q.S. Zhao, Int. J. Pharm. Pharm. Sci., 3, 418 (2011).
M. Ajaib, N. Javed and E.H. Siddiqi, Pharmacologyonline, 1, 135 (2013).
C.K. Joshi, P. Singh and L.C. Singhi, J. Indian Chem. Soc., 60, 905 (1983).
E. Helfrich and H. Rimpler, Phytochemistry, 50, 619 (1999); https://doi.org/10.1016/S0031-9422(98)00559-7.
P.K. Chaudhari, M. Sing, M. Pal, R.P. Sharma and S.P. Jain, Indian J. Chem., 38B, 632 (1999) .
I.E. Oboh, J.O. Akerele and O. Obasuyi, Tropical J. Pharm. Res., 6, 809 (2007); https://doi.org/10.4314/tjpr.v6i4.3.
C. Perez, M. Pauli and P. Bazerque, Acta Biol. Med. Exp., 15, 113 (1990).
I. Wiegand, K. Hilpert and R.E.W. Hancock, Nat. Protoc., 3, 163 (2008); https://doi.org/10.1038/nprot.2007.521.
J. Shinoda, J. Pharm. Soc. Japan, 48, 218 (1928).
T.J. Mabry, K.R. Markham and M.B. Thomas, The Systematic Identification of Flavonoids, Springer-Verlag: Berlin (1970).
W.A. Bubb, Concepts Magn. Reson. Part A, 19A, 1 (2003); https://doi.org/10.1002/cmr.a.10080.
J.Ø. Duus, C.H. Gotfredsen and K. Bock, Chem. Rev., 100, 4589 (2000); https://doi.org/10.1021/cr990302n.
R.N. Yadava and P. Yadav, Am. J. Phytomed. Clin. Therap., 1, 672 (2013).
J.M. Bobbitt, Adv. Carbohydrate Chem., 11, 1 (1956).
N.P.J. Price, Appl. Biochem. Biotechnol., 148, 271 (2008); https://doi.org/10.1007/s12010-007-8044-8.
J.B. Harborne, Phytochemistry, 4, 107 (1965); https://doi.org/10.1016/S0031-9422(00)86152-X.