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Triterpenes and Sterols from Terminalia foetidissima Griff.
Corresponding Author(s) : Consolacion Y. Ragasa
Asian Journal of Chemistry,
Vol. 31 No. 11 (2019): Vol 31 Issue 11
Abstract
Terminalia foetidissima Griff. is a tree native of the Philippines. Chemical investigation of dichloromethane extract of the leaves of T. foetidissima has led to the isolation of cycloeucalenol (1), squalene (2), long-chain hydrocarbons (3) and a mixture of 24-methylene-pollinastanol (4), β-sitosterol (5) and stigmasterol (6) in about 4:3:1 ratio. The structure of compound 1 was elucidated by extensive 1D and 2D NMR spectroscopy and confirmed by comparison of its NMR data with those reported in the literature. The structures of compounds 2-6 were identified by comparison of their NMR data with literature data.
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- Tropical Plants Database, Ken Fern. tropical.theferns.info. 2018-12-20. .
- C.Y. Ragasa, V.A.S. Ng, V.D. Ebajo Jr. and D.R. Fortin, Der Pharm. Chem., 6, 453 (2014).
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- T. Ghosh, T.K. Maity and J. Singh, Orient. Pharm. Exp. Med., 11, 41 (2011); https://doi.org/10.1007/s13596-011-0001-y.
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References
Tropical Plants Database, Ken Fern. tropical.theferns.info. 2018-12-20. .
C.Y. Ragasa, V.A.S. Ng, V.D. Ebajo Jr. and D.R. Fortin, Der Pharm. Chem., 6, 453 (2014).
T. Kikuchi, S. Kadota and K. Tsubono, Chem. Pharm. Bull. (Tokyo), 34, 2479 (1986); https://doi.org/10.1248/cpb.34.2479.
C.Y. Ragasa, V.A.S. Ng, M.M. De Los Reyes, E.H. Mandia, G.G. Oyong and C.-C. Shen, Der Pharm. Chem., 6, 182 (2014).
V.D. Ebajo Jr., R. Brkljaèa, S. Urban and C.Y. Ragasa, J. Appl. Pharm. Sci., 5, 69 (2015).
M.J. Thompson, S.R. Dutky, Y. Lehner, L.N. Standifier and E.W. Herbert Jr., Phytochemistry, 17, 1053 (1978); https://doi.org/10.1016/S0031-9422(00)94279-1.
C.Y. Ragasa, G.S. Lorena, E.H. Mandia, D.D. Raga and C.-C. Shen, Am. J. Essent. Oils Nat. Prod., 1, 7 (2013).
C.V. Rao, H.L.N. Mark and R.S. Reddy, Carcinogenesis, 19, 287 (1998); https://doi.org/10.1093/carcin/19.2.287.
K.H.S. Farvin, R. Anandan, S.H.S. Kumar, K.S. Shiny, S. Mathew,T.V. Sankar and P.G.V. Nair, J. Med. Food, 9, 531 (2006); https://doi.org/10.1089/jmf.2006.9.531.
R. Loganathan, K.R. Selvaduray, K. Nesaretnam and A. Radhakrisnan, J. Oil Palm Res., 25, 208 (2013).
K.N. Desai, H. Wei and C.A. Lamartiniere, Cancer Lett., 101, 93 (1996); https://doi.org/10.1016/0304-3835(96)04122-5.
A.L. Ronco and E. De Stéfani, Funct. Food Health Dis., 3, 462 (2013); https://doi.org/10.31989/ffhd.v3i12.30.
T. Ghosh, T.K. Maity and J. Singh, Orient. Pharm. Exp. Med., 11, 41 (2011); https://doi.org/10.1007/s13596-011-0001-y.
A.K. Batta, G. Xu, A. Honda, T. Miyazaki and G. Salen, Metabolism, 55, 292 (2006); https://doi.org/10.1016/j.metabol.2005.08.024.
M.A. Gómez, M.D. García and M.T. Sáenz, Phytother. Res., 15, 633 (2001); https://doi.org/10.1002/ptr.837.
Y. Kasahara, K. Kumaki, S. Katagiri, K. Yasukawa, S. Yamanouchi, M. Takido, T. Akihisa and T. Tamura, Phytother. Res., 8, 327 (1994); https://doi.org/10.1002/ptr.2650080603.
J.-C. Lim, J.H. Park, M. Budesinsky, A. Kasal, Y.-H. Han, B.-S. Koo, S.-I. Lee and D.-U. Lee, Chem. Pharm. Bull. (Tokyo), 53, 561 (2005); https://doi.org/10.1248/cpb.53.561.
M.D. García, M.T. Sáenz, M.A. Gómez and M.A. Fernández, Phytother. Res., 13, 78 (1999); https://doi.org/10.1002/(SICI)1099-1573(199902)13:1<78::AIDPTR384>3.0.CO;2-F.
O. Gabay, C. Sanchez, C. Salvat, F. Chevy, M. Breton, G. Nourissat, C. Wolf, C. Jacques and F. Berenbaum, Osteoarthritis Cartilage, 18, 106 (2010); https://doi.org/10.1016/j.joca.2009.08.019.
S. Panda, M. Jafri, A. Kar and B.K. Meheta, Fitoterapia, 80, 123 (2009); https://doi.org/10.1016/j.fitote.2008.12.002.
A.B. Awad, M. Chinnam, C.S. Fink and P.G. Bradford, Phytomedicine, 14, 747 (2007); https://doi.org/10.1016/j.phymed.2007.01.003.
G.K. Jayaprakasha, K.K. Mandadi, S.M. Poulose, Y. Jadegoud, G.A. Gowda and B.S. Patil, Bioorg. Med. Chem., 15, 4923 (2007); https://doi.org/10.1016/j.bmc.2007.04.044.
A.A. Baskar, S. Ignacimuthu, G.M. Paulraj and K.S. Al Numair, BMC Comp. Alternat. Med., 10, 24 (2010); https://doi.org/10.1186/1472-6882-10-24.
E.D. Jesch, J.M. Seo, T.P. Carr and J.Y. Lee, Nutr. Res., 29, 859 (2009); https://doi.org/10.1016/j.nutres.2009.10.016.
D.-O. Moon, K.-J. Lee, Y.H. Choi and G.-Y. Kim, Int. Immunopharmacol., 7, 1044 (2007); https://doi.org/10.1016/j.intimp.2007.03.010.