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A Novel Pyridyl Ester Isolated from Leucas cephalotes
Corresponding Author(s) : K. Kavitha Priya
Asian Journal of Chemistry,
Vol. 31 No. 10 (2019): Vol 31 Issue 10
Abstract
From the flowers of Leucas cephalotes, pyridine-3-carboxylic acid ester was isolated. Its structure was established as 2′,5′-dihydroxy-3′-pyridyl-(2,5-dihydroxy)pyridinyl-3-carboxylate on the basis of spectroscopic analysis. To out best of knowledge, this is the first report from Leucas cephalotes in particular and Labiatae family in general.
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- S. Chouhan and S.K. Singh, J. Pharmacogn. Phytother., 3, 13 (2011).
- P. Bhandari, N.K. Patel and K.K. Bhutani, Bioorg. Med. Chem. Lett., 24, 3596 (2014); https://doi.org/10.1016/j.bmcl.2014.05.032.
- N. Katsui, H. Matsui, T. Hirata and T. Masamune, Bull. Chem. Soc. Jpn, 45, 223 (1972);
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- S. Gallipalli, N.K. Patel, K. Prasanna and K.K. Bhutani, Nat. Prod. Res., 29, 1670 (2015); https://doi.org/10.1080/14786419.2014.989846.
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- R.B. Shinde, V.A. Jagtap, U.P. Joshi, R.B. Patil and R.D. Wagh, Int. J. Drug Discov. Herbal Res., 1, 25 (2011).
- A. Katara, C.K. Pradhan, A.K. Tyagi and P. Singh, J. Nat. Prod. Plant Resour., 2, 284 (2010).
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- J.K. Wilmshurt and H.J. Bernstein, Can. J. Chem., 35, 1183 (1957); https://doi.org/10.1139/v57-159.
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References
S. Chouhan and S.K. Singh, J. Pharmacogn. Phytother., 3, 13 (2011).
P. Bhandari, N.K. Patel and K.K. Bhutani, Bioorg. Med. Chem. Lett., 24, 3596 (2014); https://doi.org/10.1016/j.bmcl.2014.05.032.
N. Katsui, H. Matsui, T. Hirata and T. Masamune, Bull. Chem. Soc. Jpn, 45, 223 (1972);
P. Bhandari, N.K. Patel, R.P. Gangwal, A.T. Sangamwar and K.K. Bhutani, Bioorg. Med. Chem. Lett., 24, 4114 (2014); https://doi.org/10.1016/j.bmcl.2014.07.056.
S. Gallipalli, N.K. Patel, K. Prasanna and K.K. Bhutani, Nat. Prod. Res., 29, 1670 (2015); https://doi.org/10.1080/14786419.2014.989846.
M.O. Bagby, C.R. Smith Jr and I.A. Wolff, J. Org. Chem., 30, 4227 (1965); https://doi.org/10.1021/jo01023a055.
N.K. Patel, M.S. Khan and K.K. Bhutani, EXCLI J., 14, 508 (2015); https://doi.org/10.17179/excli2014-667.
N. Singh, R. Nath, M.L. Gupta and R.P. Kohli, Q. J. Crude Drugs Res., 16, 8 (1978); https://doi.org/10.3109/13880207809083247.
M. Kamat and T.P. Singh, Geobios, 21, 31 (1994).
Y. Miyaichi, A. Segawa and T. Tomimuri, Chem. Pharm. Bull., 54, 1370 (2006); https://doi.org/10.1248/cpb.54.1370.
R. Bhoria and S. Kainsa, Int. J. Pharm., 3, 77 (2013).
K.H. Nadkarni, Indian Materica Medica, Bombay Popular Parkashan: Bombay, India, vol. 1, 739 (2007).
J.F. Caius, The Medical and Poisonous Plants of India, NISCAIR: CSIR, New Delhi, vol. 6, 79 (2003).
A. Mathur, S.K. Verma, S.K. Singh, G.B.K.S. Prasad and V.K. Dua, J. Pharmacog. Herbal formul., 2, 284 (2010).
R.B. Shinde, V.A. Jagtap, U.P. Joshi, R.B. Patil and R.D. Wagh, Int. J. Drug Discov. Herbal Res., 1, 25 (2011).
A. Katara, C.K. Pradhan, A.K. Tyagi and P. Singh, J. Nat. Prod. Plant Resour., 2, 284 (2010).
J.H. Bavarva an A.V.R.L. Narasimhacharya, J. Ethnopharmacol., 127, 98 (2010); https://doi.org/10.1016/j.jep.2009.09.042.
K.D. Bahadur and A.B. Sen, Q. J. Crude Drug. Res., 9, 1453 (1969); https://doi.org/10.3109/13880206909066289.
P. Kooiman, Acta Bot. Neerl., 21, 417 (1972); https://doi.org/10.1111/j.1438-8677.1972.tb00795.x.
S.C. Chen, R.M. Elofson and J.M. Mactaggart, J. Agric. Food Chem., 27, 435-438 (1979); https://doi.org/10.1021/jf60222a028.
W.O. George, T.E. Houston and W.C. Harris, Spectrochim. Acta A: Mol. Spectrosc., 30, 1035 (1974); https://doi.org/10.1016/0584-8539(74)80020-6.
W. Kemp, Organic Spectroscopy, Macmillan International Higher Education: New York, edn 3, pp 177-203 (1991).
J.K. Wilmshurt and H.J. Bernstein, Can. J. Chem., 35, 1183 (1957); https://doi.org/10.1139/v57-159.
M.L. Swain, A. Eisner, C.F. Woodward and B.A. Brice, J. Am. Chem. Soc., 71, 1341 (1949); https://doi.org/10.1021/ja01172a057.
L. Jayasinghe, C.P. Jayasooriya, N. Hara and Y. Fujimoto, Tetrahedron Lett., 44, 8769 (2003); https://doi.org/10.1016/j.tetlet.2003.09.177
C. Diana, G.A. Pinto, M. Clemantina, M .Santos and Artur M.S. Silva, ed.: T.M.V.D. Pinho e Melo, Advanced NMR Techniques for Structural Characterization of Heterocyclic Structures, Recent Research Developments in Heterocyclic Chemistry, pp 397-475 (2007).
R.M. Silverstein, G.C. Bassler and T.C. Morrill; Spectrometric Identification of Organic Compounds, Wiley: Chichester, edn 5, pp 176-177 (1991).
J. Stankeviciute, J. Vaitekunas, V. Petkevicius, R. Gasparaviciute, D. Tauraite and R. Meškys, Scient. Rep., 6, 39129 (2016); https://doi.org/10.1038/srep39129.
R.M. Silverstein, G.C. Bassler and T.C. Morrill; Spectrometric Identification of Organic Compounds, Wiley: Chichester, edn 5, pp 234-250 (1991).
N.A. Zaidi, J.M. Al-Katti and F.H. Saeed, J. Chem. Soc. Pak., 3, 63 (1981).