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Vol. 31 No. 10 (2019): Vol 31 Issue 10

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One Pot Microwave Induced Synthesis, Characterization and Antibacterial Activity of Tetrazamacrocyclic Complexes of Transition Metal Ions of Bio-Inorganic Relevance

https://doi.org/10.14233/ajchem.2019.22110
Devendra Kumar
Department of Chemistry, Institute of Basic Sciences, Dr. Bhimrao Ambedkar University, Khandari Campus, Agra-282002, India
Saraswati
Department of Chemistry, Institute of Basic Sciences, Dr. Bhimrao Ambedkar University, Khandari Campus, Agra-282002, India

Corresponding Author(s) : Devendra Kumar

devendrakumar131@gmail.com

Asian Journal of Chemistry, Vol. 31 No. 10 (2019): Vol 31 Issue 10

Abstract

Two new series of metal complexes, [M(C18H16N4O4)·2H2O] (CH3COO−)2 and [M(C22H24N4)·2H2O] (CH3COO−)2, where M= Co2+/Ni2+/Cu2+ have been prepared under microwave irradiation condition using microwave synthesizer. All the synthesized compounds were characterized by melting point determination of recrystallized samples, running single spot on TLC, elemental analyses, IR, UV-visible spectral studies. Synthesized macrocyclic complexes have been tested for their antibacterial activity against two bacteria Klebsiella pneumoniae and Escherichia coli by adopting disk diffusion method. The antibacterial activity was compared with amikacin antibiotic and it has been found that the complexes exhibited potential antibacterial activity. From the antibacterial studies, it has been found that the copper complexes were more effective on the microorganism in comparison to Ni(II) and Co(II) complexes.

Keywords

Transition metal(II) complexes Tetrazamacrocyclic ligand Infra-Red UV-Visible Antibacterial activity
Kumar, D., & Saraswati, . (2019). One Pot Microwave Induced Synthesis, Characterization and Antibacterial Activity of Tetrazamacrocyclic Complexes of Transition Metal Ions of Bio-Inorganic Relevance. Asian Journal of Chemistry, 31(10), 2211–2214. https://doi.org/10.14233/ajchem.2019.22110
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