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Vol. 20 No. 6 (2008): Vol 20 Issue 6

Copyright (c) 2008 D. Gowri Sankar, A. Nagesh Babu, A. Rajeswari, M. Vamsi Krishna, K. Vanisha Devi

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Spectrophotometric Determination of Zolmitriptan in Pharmaceutical Dosage Forms

D. Gowri Sankar
Department of Pharmaceutical Analysis and Quality Assurance, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India
A. Nagesh Babu
Department of Pharmaceutical Analysis and Quality Assurance, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India
A. Rajeswari
Department of Pharmaceutical Analysis and Quality Assurance, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India
M. Vamsi Krishna
Department of Pharmaceutical Analysis and Quality Assurance, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India
K. Vanisha Devi
Department of Pharmaceutical Analysis and Quality Assurance, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India

Corresponding Author(s) : D. Gowri Sankar

gowrisankar97@rediffmail.com

Asian Journal of Chemistry, Vol. 20 No. 6 (2008): Vol 20 Issue 6

Abstract

A new UV spectrophotometric method has been developed for the quantitative estimation of zolmitriptan in pure form as well as in pharmaceutical formulations. The drug exhibits absorption maximum at 226 nm in methanol and obeys Beer's law in the concentration range of 1-6 μg/mL. The method was extended to pharmaceutical preparations and there is no interference from any common pharmaceutical additives.

Keywords

UV-Spectrophotometric Zolmitriptan
(1)
Sankar, D. G.; Babu, A. N.; Rajeswari, A.; Krishna, M. V.; Devi, K. V. Spectrophotometric Determination of Zolmitriptan in Pharmaceutical Dosage Forms. ajc 2010, 20, 4960-4962.
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