Synthesis and Antimicrobial Screening of Bivalent Metal Ion Complexes with Schiff Base Derived from 3,4-Diethyl Isoquinolone

Abstract

The Co(II), Ni(II) and Cu(II) complexes have been synthesized with 3,4-diethyl isoquinolone thiosemicarbazone [DIQT]. All the complexes were identified and confirmed by elemental analyses, IR spectra, electronic spectra, molar conductivity, molar mass and magnetic susceptibility data. The molar conductance measurements revealed that the prepared complexes are non-electrolytic in nature. The magnetic susceptibility and electronic spectral data indicates the geometry of the complexes is octahedral in nature. Their spectral data proposed the coordination sites of the free ligand with the central metal ion through azomethine N and thione S. The remaining coordination positions are satisfied through negative ions such as Cl^–, Br^–, I^–, NO₃^– and ClO₄^–. The ligand and its metal complexes were tested for their antimicrobial activity against Aspergillus niger and Aspergillus flavous.