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Vol. 36 No. 4 (2024): Vol 36 Issue 4, 2024

Copyright (c) 2024 Dr. Hamid Khan Dr. Hamid Khan

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This work is licensed under a Creative Commons Attribution 4.0 International License.

UHPLC-MS/MS Technique: Applications in Analytical Chemistry

https://doi.org/10.14233/ajchem.2024.31383
Hamid Khan
Bhagwan Aadinath College of Pharmacy, Lalitpur-284403, India
https://orcid.org/0009-0000-0343-9746

Corresponding Author(s) : Hamid Khan

khanhamid770@gmail.com

Asian Journal of Chemistry, Vol. 36 No. 4 (2024): Vol 36 Issue 4, 2024

Abstract

The ultra-high performance liquid chromatography-mass spectrometry/mass spectrometry (UHPLC-MS/MS) is becoming most advanced technique used for analysis of wide range of compounds in analytical chemistry. This technique has been effectively utilized for identifying and quantitatively determining substances in several pharmaceutical analysis fields. The UHPLC technique offers superior sensitivity, selectivity and peak shape in comparison to the conventional HPLC technique. The UHPLC coupled with various mass spectrometers gives accurate mass fragmentations which is ultimately helpful in structural identification and quantitative determination of compounds. The review provides brief introduction on development of UHPLC column packing materials and coupled mass detectors such as single quadrupole, triple quadrupole and time-of-flight mass. This review article also summarizes application of UHPLC-MS/MS technique in various fields of analytical chemistry.

Keywords

UHPLC-MS/MS UPLC Applications Analytical chemistry
Khan, H. (2024). UHPLC-MS/MS Technique: Applications in Analytical Chemistry. Asian Journal of Chemistry, 36(4), 766–778. https://doi.org/10.14233/ajchem.2024.31383
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References
  1. M.E. Swartz, J. Liq. Chromatogr. Relat. Technol., 28, 1253 (2005); https://doi.org/10.1081/JLC-200053046
  2. S.A.C. Wren and P. Tchelitcheff, J. Chromatogr. A, 1119, 140 (2006); https://doi.org/10.1016/j.chroma.2006.02.052
  3. S.M. Chesnut and J.J. Salisbury, J. Sep. Sci., 30, 1183(2007); https://doi.org/10.1002/jssc.200600505
  4. J.C. Piontek, P. Zalewski, A. Jelinska and P. Garbacki, Chromatographia, 76, 1429 (2013); https://doi.org/10.1007/s10337-013-2434-6
  5. L. Novakova, L. Matysova and P. Solich, Talanta, 68, 908(2006); https://doi.org/10.1016/j.talanta.2005.06.035
  6. S.K. Pramod and KA Navnath, World J. Pharm. Res., 6, 407 (2017).
  7. L. Novakova, L. Matysova and P. Solich, J Sep. Sci., 29, 2433 (2006); https://doi.org/10.1002/jssc.200600147
  8. G. Chawla and C. Ranjan, Open Chem., 3, 1 (2016); https://doi.org/10.2174/1874842201603010001
  9. S.A.C. Wren, J. Pharm. Biomed. Anal., 38, 337 (2005); https://doi.org/10.1016/j.jpba.2004.12.028
  10. N. Wu, J.A. Lippert and M.L. Lee, J. Chromotogr. A, 911, 1 (2001); https://doi.org/10.1016/s0021-9673(00)01188-2
  11. J.R. Mazzeo, U.D. Neue, M. Kale and R.S. Plumb, Anal. Chem., 77, 460A (2005); https://doi.org/10.1021/ac053516f
  12. J.E. MacNair, K.D. Patel, K.C. Lewis and J.W. Jorgenson, Anal. Chem., 69, 983 (1997); https://doi.org/10.1021/ac961094r
  13. T.H. Walter and R.W. Andrews, TrAC Trends Anal. Chem., 63, 14 (2014); https://doi.org/10.1016/j.trac.2014.07.016
  14. J.S. Mellors and J.W. Jorgenson, Anal. Chem., 76, 5441 (2004); https://doi.org/10.1021/ac049643d
  15. M.M. Fallas, U.D. Neue, M.R. Hadley and D.V. McCalley, J. Chromatogr. A, 1217, 276 (2010); https://doi.org/10.1016/j.chroma.2009.11.041
  16. L. Tolley, J.W. Jorgenson and M.A. Mosely, Anal. Chem., 73, 2985 (2001); https://doi.org/10.1021/ac0010835
  17. J. Xue, J.E. Derks, W. Webb, E.M Billings, A. Aisporna, M. Giera and G. Siuzdak, Anal. Chem., 93, 10879 (2021); https://doi.org/10.1021/acs.analchem.1c01246
  18. I.V. Chernushevich, A.V. Loboda and B.A. Thomson, J. Mass Spectrom., 36, 849 (2001); https://doi.org/10.1002/jms.207
  19. J. Castro-Perez, R. Plumb, J. Granger, I. Beattie, K. Joncour and A. Wright, Rapid Commun. Mass Spectrom., 19, 843 (2005); https://doi.org/10.1002/rcm.1859
  20. R. Plumb, J. Castro-Perez, J. Granger, I. Beattie, K. Joncour and A. Wright, Rapid Commun. Mass Spectrom., 18, 2331 (2004); https://doi.org/10.1002/rcm.1627
  21. V.K. Vyas, M. Ghate and R.D. Ukawala, Curr. Pharm. Anal., 6, 299 (2010); https://doi.org/10.2174/157341210793292392
  22. R.H. Rathod, S.R. Choudhari, A.S. Patil and A.A. Shirkhedkar, Future J. Pharm. Sci., 5, 1 (2019); https://doi.org/10.1186/s43094-019-0007-8
  23. H. Khan and J. Ali, Asian J. Pharm. Anal., 7, 124 (2017); https://doi.org/10.5958/2231-5675.2017.00020.5
  24. H. Khan and J. Ali, Lett. Org. Chem., 12, 371 (2015); https://doi.org/10.2174/1570178612666150331204147
  25. H. Khan and J. Ali, Asian J. Pharm. Anal., 7, 31 (2017); https://doi.org/10.5958/2231-5675.2017.00006.0
  26. H. Khan, H. Ali, S. Ahmad, N. Ahmad, A. Ahuja, S. Baboota and J. Ali, J. Liq. Chromatogr. Relat. Technol., 35, 109 (2012); https://doi.org/10.1080/10826076.2011.597063
  27. R.P. Shah and S. Singh, J. Pharm. Biomed. Anal., 53, 755 (2010); https://doi.org/10.1016/j.jpba.2010.05.005
  28. H. Khan, M. Ali, A. Ahuja and J. Ali, Asian J. Res. Pharm. Sci., 7, 105 (2017); https://doi.org/10.5958/2231-5659.2017.00016.9
  29. H. Khan, Asian J. Pharm. Res., 11, 1 (2021); https://doi.org/10.5958/2231-5691.2021.00001.0
  30. Y. Wang, C.G. Song, J. Yang, T. Zhou, Y. Zhao, J. Qin, L. Guo and G. Ding, Front. Chem., 9, 789249 (2021); https://doi.org/10.3389/fchem.2021.789249
  31. K.K. Hotha, T. Patel, S. Roychowdhury and V. Subramanian, J. Liq. Chromatogr. Relat. Technol., 38, 977 (2015); https://doi.org/10.1080/10826076.2014.999201
  32. S. Mowaka and D. Mohamed, RSC Adv., 5, 60467 (2015); https://doi.org/10.1039/C5RA11448A
  33. C. Liu, Z. Hua and Y. Bai, Forensic Sci. Int., 257, 196 (2015); https://doi.org/10.1016/j.forsciint.2015.08.009
  34. A.V. Reddy, N. Venugopal, G. Madhavi, K.G. Reddy and V. Madhavi, J. Pharm. Biomed. Anal., 84, 84 (2013); https://doi.org/10.1016/j.jpba.2013.05.047
  35. N.R. Wingert, N.O. Santos, M.A. Nunes, P. Gomes, E.I. Muller, E.M. Flores and M. Steppe, J. Pharm. Biomed. Anal., 123, 10 (2016); https://doi.org/10.1016/j.jpba.2016.01.053
  36. U. Hubicka, P. Zmudzki, B.Z. Witek, P. Zajdel, M. Pawlowski and J. Krzek, Talanta, 109, 91 (2012); https://doi.org/10.1016/j.talanta.2013.01.055
  37. M. K. Moorthy, M.A. Shaik and V.S. Gopireddy, Chromatographia, 85, 137 (2022); https://doi.org/10.1007/s10337-021-04123-x
  38. H. Khan, World J. Pharm. Res., 7, 607 (2018).
  39. H. Khan, M. Ali, A. Ahuja and J. Ali, Asian J. Pharm. Anal., 7, 93 (2017); https://doi.org/10.5958/2231-5675.2017.00016.3
  40. H. Khan, M. Ali, A. Ahuja and J. Ali, Res. J. Pharm. Tech., 9, 1441 (2016); https://doi.org/10.5958/0974-360X.2016.00278.X
  41. H. Khan, M. Ali, A. Ahuja and J. Ali, Asian J. Pharm. Technol., 7, 27 (2017); https://doi.org/10.5958/2231-5713.2017.00005.8
  42. H. Khan, Asian J. Pharm. Anal., 11, 22 (2021); https://doi.org/10.5958/2231-5675.2021.00004.1
  43. D. Wang, K. Jiang, S. Yang, F. Qin, X. Lu and F. Li, J. Chromatogr. B, 879, 1827 (2011); https://doi.org/10.1016/j.jchromb.2011.04.034
  44. Y. Ma, F. Qin, X. Sun, X. Lu and F. Li, J. Pharm. Biomed. Anal., 43, 1540 (2007); https://doi.org/10.1016/j.jpba.2006.11.015
  45. H.H. Lee, S.H. Im, S. Ahn, M.A. Bae, S.B. Park, S.K. Kim, J. Sook and S. Song, J. Pharm. Biomed. Anal., 166, 183 (2019); https://doi.org/10.1016/j.jpba.2019.01.013
  46. C. Huang, W. Wang and L. Miao, J. Chromatogr. Sci., 52, 636 (2014); https://doi.org/10.1093/chromsci/bmt092
  47. H. Sun, Q. Yin, A. Zhang and X. Wang, J. Sep. Sci., 35, 2063 (2012); https://doi.org/10.1002/jssc.201200378
  48. X. Wang, F. Qin, L Jing, Q. Zhu, F. Li and Z. Xiong, Biomed. Chromatogr., 27, 371 (2013); https://doi.org/10.1002/bmc.2801
  49. A. Bhadoriya, P. A. Shah, P.S. Shrivastav, K.D. Bharwad and P. Singhal, Biomed. Chromatogr., 33, e4543 (2019); https://doi.org/10.1002/bmc.4543
  50. Y. Xu, X. Gao, Y. Zhu, Q. Zhang, H. Qie, H. Zhao, J. Gao and M. Wang, Drug Des. Develop. Ther., 17, 3551 (2023); https://doi.org/10.2147/DDDT.S434492
  51. R.M. Tony, M.A. El-Hamd, M. Gamal, S.F. Saleh, N. Maslamani, W.T. Alsaggaf and M.B. El-Zeiny, Separations, 10, 234 (2023); https://doi.org/10.3390/separations10040234
  52. M.A. Alam, N. Ahmad, R. Ahmad, S. Talegaonkar, F.J. Ahmad, Z. Iqbal and A.K. Panda, J. Young Pharmacists, 8, 415 (2016); https://doi.org/10.5530/jyp.2016.4.18
  53. T. Menaka and R. Kuber, J. Appl. Pharm. Sci., 13, 201 (2023); https://doi.org/10.7324/JAPS.2023.130120
  54. A. Alamir, J. Watterson and I. Attafi, Separations, 9, 285 (2022); https://doi.org/10.3390/separations9100285
  55. K.A. Johnson and R. Plumb, J. Pharm. Biomed. Anal., 39, 805 (2005); https://doi.org/10.1016/j.jpba.2005.04.048
  56. J. Mao, Y. Xu, B. Lu, J. Liu, G. Hong, Q. Zhang, S. Sun and J. Zhang, Anal. Bioanal. Chem., 407, 4101 (2015); https://doi.org/10.1007/s00216-015-8643-0
  57. M. Carlier, V. Stove, J.A. Roberts, E.V. de Velde, J.J. De Waele and A.G. Verstraete, Int. J. Antimicrob. Agents, 40, 416 (2012); https://doi.org/10.1016/j.ijantimicag.2012.06.022
  58. S.Q. Zhang and G.H. Chen, J. Chromatogr. Sci., 46, 220 (2008); https://doi.org/10.1093/chromsci/46.3.220
  59. L. van Haandel, M.L. Becker, T.D. Williams, J.S. Leeder and J.F. Stobaugh, Bioanalysis, 3, 2783 (2011); https://doi.org/10.4155/bio.11.288
  60. F. Yang, H. Wang, P. Hu and J. Jiang, J. Chromatogr. Sci., 53, 974 (2014); https://doi.org/10.1093/chromsci/bmu164
  61. G. Abdelbary and M. Nebsen, J. Pharm. Res., 7, 24 (2013); https://doi.org/10.1016/j.jopr.2013.01.010
  62. T.A. Wani and S. Zargar, J. Food Drug Anal., 23, 569 (2015); https://doi.org/10.1016/j.jfda.2015.02.008
  63. M.R. Rezk and K.A. Badr, J. Pharm. Biomed. Anal., 98, 1 (2014); https://doi.org/10.1016/j.jpba.2014.05.005
  64. X. Qiu, S. L. Zheng, Y. Wang, R. Wang and L. Ye, J. Chromatogr. Sci., 53, 85 (2014); https://doi.org/10.1093/chromsci/bmu023
  65. L. Baietto, A. Calcagno, I. Motta, K. Baruffi, V. Poretti, P. G. Di, S. Bonora and A. D’avolio, J. Antimicrob. Chemother., 70, 2572 (2015); https://doi.org/10.1093/jac/dkv148
  66. S. Lachowicz, J. Oszmiañski, A. Wojdylo, T. Cebulak, L. Hirnle and M. Siewiñski, Eur. Food Res. Technol., 245, 691 (2019); https://doi.org/10.1007/s00217-018-3191-4
  67. J. Wu, X. Fang, Y. Yuan, Y. Dong, Y. Liang, Q. Xie, J. Ban, Y. Chen and Z. Lva, Rev. Brasil. Farmacog., 27, 716 (2017); https://doi.org/10.1016/j.bjp.2017.10.005
  68. S. Kivrak, G. Tolga, K. Ibrahim, K. Ergun and K. Ersan, Food Sci. Technol., 39, 423 (2019); https://doi.org/10.1590/fst.32017
  69. N. Ortega, M.-P. Romero, A. Macià, J. Reguant, N. Anglès, J.-R. Morelló and M.-J. Motilva, J. Food Comp. Anal., 23, 298 (2010); https://doi.org/10.1016/j.jfca.2009.10.005
  70. F.S. Rabaneda, O. Jáuregui, I. Casals, C.A. Lacueva, M.I. Pulido and R.L. Raventós, J. Mass Spectrom., 38, 35 (2003); https://doi.org/10.1002/jms.395
  71. W.T. Jeong and H.B. Lim, J. Chromatogr B., 1080, 27 (2018); https://doi.org/10.1016/j.jchromb.2018.02.018
  72. H. Wang, W. Qi, L. Zhang and D. Yuan, Chem. Pharm. Bull., 62, 1100 (2014);https://doi.org/10.1248/cpb.c14-00481
  73. Z. Wang, D. Wang, W. Liu and Z. Wang, iLiver, 2, 181 (2023); https://doi.org/10.1016/j.iliver.2023.08.004
  74. Z. Chen, C.T. Vong, T. Zhang, C. Yao, Y. Wang and H. Luo, Chin. Med., 18, 126 (2023); https://doi.org/10.1186/s13020-023-00836-3
  75. D. Ma, S. Wang, Y. Shi, S. Ni, M. Tang and A. Xu, J. Trad. Chin. Med. Sci., 8, S1 (2021); https://doi.org/10.1016/j.jtcms.2021.11.002
  76. J. Ma, K. Li, S. Shi, J. Li, S. Tang and L. Liu, Front. Pharmacol., 13, 922488 (2022); https://doi.org/10.3389/fphar.2022.922488
  77. F. Leong, X. Hua, M. Wang, T. Chen, Y. Song, P. Tu and X.-J. Chen, Chinese Med., 15, 76 (2020); https://doi.org/10.1186/s13020-020-00357-3
  78. C.-Y. Hsieh, C.-C. Wang, L.L. Tayo, P.-W. Tsai and C.-J. Lee, J. Food Drug Anal., 31, 502 (2023); https://doi.org/10.38212/2224-6614.3473
  79. P. Wang, S. Jiang, Y. Zhao, S. Sun, X. Wen, X. Guo and Z. Jiang, Curr. Pharm. Anal., 15, 231 (2019); https://doi.org/10.2174/1573412914666180409143452
  80. H.Y. Yan, Z. Wang, F. Xia, W. Yang, Y.-C. Liu and J.-B. Wan, Chin. Med., 16, 26 (2021); https://doi.org/10.1186/s13020-021-00435-0
  81. G. Liu, S. Qiao, T. Liu, H. Yu, W. Wang, Y. Zhou, Q. Li and S. Li, J. Chromatogr. Sci., 54, 1540 (2016); https://doi.org/10.1093/chromsci/bmw099
  82. Z. Li, X. Zhang, J. Liao, X. Fan and Y. Cheng, J. Pharm. Anal., 11, 88 (2011); https://doi.org/10.1016/j.jpha.2020.01.003
  83. H. Li, W. Yao, Q. Liu, J. Xu, B. Bao, M. Shan, Y. Cao, F. Cheng, A. Ding and L. Zhang, Molecules, 22, 689 (2017); https://doi.org/10.3390/molecules22050689
  84. X.J. Lv, Z. Sun, P.L. Wang, J. Yang, T.Y. Xu, Q.Q. Jia, D.-W. Li, F.-Y. Su, Z.-F. Zhu, J. Kang and X.-J. Zhang, J. Pharm. Biomed. Anal., 148, 189 (2018); https://doi.org/10.1016/j.jpba.2017.09.034
  85. X.X. Zong, Y. Wang, J.L. Xiong, Y.H. Ping and Q.L. Liang, Nat. Prod. Res., 36, 429 (2022); https://doi.org/10.1080/14786419.2020.1771712
  86. F.X. Zhang, M. Li, Z.H. Yao, C. Li, L.-R. Qiao, X.-Y. Shen, K. Yu, Y. Dai and X.-S. Yao, Biomed. Chromatogr., 32, e4110 (2018); https://doi.org/10.1002/bmc.4110
  87. L. Zhang, Z. Jiang, J. Yang, Y. Li, Y. Wang and X Chai, J. Food Drug Anal., 23, 811 (2009); https://doi.org/10.1016/j.jfda.2015.06.004
  88. X.B. Wang, J. Zheng, J.J. Li, H.Y. Yu, Q.Y. Li, L.H. Xu, M.-J. Liu, R.-Q. Xian, Y.-E. Sun and B.-J. Liu, J. Food Drug Anal., 26, 1138 (2018); https://doi.org/10.1016/j.jfda.2018.02.003
  89. Y. Wang, S. He, X. Cheng, Y. Lu, Y. Zou and Q. Zhang, J. Pharm. Biomed. Anal., 80, 24 (2013); https://doi.org/10.1016/j.jpba.2013.02.021
  90. T. Yuan, X.F. Guo, S.Y. Shao, R.M. An, J. Wang and J. Sun, Acta Chromatogr., 33, 281 (2021); https://doi.org/10.1556/1326.2020.00777
  91. D. Hampel, E.R. York and L.H. Allen, J. Chromatogr. B, 903, 7 (2012); https://doi.org/10.1016/j.jchromb.2012.06.024
  92. A. Gentili, F. Caretti, G. D. Ascenzo, S. Marchese, D. Perret, D. Corcia and L. Rocca, Rapid Comm. Mass Spectrom., 22, 2029 (2008); https://doi.org/10.1002/rcm.3583
  93. B. Lu, Y. Ren, B. Huang, W. Liao, Z. Cai and X. Tie, J. Chromatogr. Sci., 46, 225 (2008); https://doi.org/10.1093/chromsci/46.3.225
  94. M. Huang, P. LaLuzerne, D. Winters and D. Sullivan, J. AOAC Int., 92, 1327 (2009); https://doi.org/10.1093/jaoac/92.5.1327
  95. Y.-S. Shim, K.-J. Kim, D. Seo, M. Ito, H. Nakagawa and J. Ha, J. AOAC Int., 95, 517 (2012); https://doi.org/10.5740/jaoacint.11-045
  96. S.S. Zhu, R. Long, T. Song, L. Zhang, Y.L. Dai, S.W. Liu and P. Zhang, Chem. Res. Toxicol., 32, 2204 (2019); https://doi.org/10.1021/acs.chemrestox.9b00233
  97. K. Spagou, I.D. Wilson, P. Masson, G. Theodoridis, N. Raikos, M. Coen, E. Holmes, J.C. Lindon, R.S. Plumb, J.K. Nicholson and E.J. Want, Anal. Chem., 83, 382 (2011); https://doi.org/10.1021/ac102523q
  98. Z. Wang, J. Liu, J. Xu, H. Zhu, M. Kong, G.-H. Zhang, S.-M. Duan, X.-Y. Li, G.-F. Li, L-F. Liu and S.-L. Li, Chinese J. Nat. Med., 15, 474 (2017); https://doi.org/10.1016/S1875-5364(17)30071-7
  99. H. Ji, Y. Wua, F. Fannin and L. Bush, Heliyon, 5, e01719 (2019); https://doi.org/10.1016/j.heliyon.2019.e01719
  100. M. Bolechová, J. Èáslavský, M. Pospíchalová and P. Kosubová, Food Chem., 170, 265 (2015); https://doi.org/10.1016/j.foodchem.2014.08.072
  101. Y. Li, T. Pang, J. Shi, X. Lu, J. Deng, Q. Deng and Q. Lin, J. Chromatogr. Sci., 53, 1730 (2015); https://doi.org/10.1093/chromsci/bmv082
  102. F. Vincenti, C. Montesano, A. Ciccola, I. Serafini, G. Favero, M. Pallotta, F. Pagano, G.D. Francesco, M. Croce, M.L. Leone, I.M. Muntoni and M. Sergi, Front. Chem., 11, 1238793 (2023); https://doi.org/10.3389/fchem.2023.1238793
  103. Z. Wang, M. Song, B. Cui, Y. Ren, W. Zhu, B. Yang and H. Kuang, J. Sep. Sci., 42, 1351 (2019); https://doi.org/10.1002/jssc.201801018
  104. L. Frommherz, H. Köhler, B. Brinkmann, M. Lehr and J. Beike, Int. J. Legal Med., 122, 109 (2008); https://doi.org/10.1007/s00414-007-0175-5
  105. T. Lv, C. Ju, B. Liu, X. Ren, G. Shan and T. Jia, Rev. Brasil. Farmacog., 29, 744 (2019); https://doi.org/10.1016/j.bjp.2019.08.005
  106. Y. Phungsiangdee, P. Chaothong, W. Karnpanit and P. Tanaviyutpakdee, Foods, 12, 3941 (2023); https://doi.org/10.3390/foods12213941
  107. Y. Xue, L. Qing, L. Yong, X. Xu, B. Hu, M. Tang and J. Xie, Molecules, 24, 3016 (2019); https://doi.org/10.3390/molecules24163016
  108. J. Mazzeo, T. Wheat, B. Gillece-Castro and Z. Lu, BioPharm Int., 19, 56 (2006).
  109. I.S. Skrull, A. Rathore and T.E. Wheat, LCGC North America, 29, 838 (2011).
  110. I.S. Skrull, A. Rathore and T.E. Wheat, LCGC North America, 29, 1052 (2011).
  111. A.A. Ghfar, S.M. Wabaidur, B.H. Ahmed, Z.A. Alothman, M.R. Khan and N.H. Al-Shaalan, Food Chem., 176, 487 (2015); https://doi.org//10.1016/j.foodchem.2014.12.035
  112. M.J. Amicuccia, A.G. Galermo, E. Nandita, T.T. Vo, Y. Liu, M. Lee, G. Xu and C.B. Lebrilla, Int. J. Mass Spectrom., 438, 22 (2019); https://doi.org/10.1016/j.ijms.2018.12.009
  113. Z. Bartosova, S.V. Gonzalez, A. Voigt and P. Bruheim, J. Chromatogr. Sci., 59, 670 (2021); https://doi.org/10.1093/chromsci/bmaa121
  114. E. Tsochatzis, M. Papageorgiou and S. Kalogiannis, Foods, 8, 514 (2019); https://doi.org/10.3390/foods8100514
  115. N. Gray, R. Zia, A. King, V.C. Patel, J. Wendon, J.W. McPhail, M. Coen, R.S. Plumb, I.D. Wilson and J.K. Nicholson, Anal. Chem., 89, 2478 (2017); https://doi.org/10.1021/acs.analchem.6b04623
  116. K. Wozny, W.D. Lehmann, M. Wozny, B.S. Akbulut and B. Brügger, Anal. Bioanal. Chem., 411, 915 (2019); https://doi.org/10.1007/s00216-018-1517-5
  117. Z. Chen, F. Lin, X. Ye, Y. Dong, L. Hu and A. Huang, Lipids Health Dis., 19, 52 (2020); https://doi.org/10.1186/s12944-020-01216-8
  118. J. Piestansky, J. Galba, D. Olesova, B. Kovacech and A. Kovac, BMC Chem., 13, 64 (2019); https://doi.org/10.1186/s13065-019-0581-z
  119. S. Wang, T. Xing, A.P. Liu, Z. He, Y. Yan, T.J. Daly and N. Li, Anal. Chem., 91, 3156 (2019); https://doi.org/10.1021/acs.analchem.8b05846
  120. P. Weber, J. Chromatogr B, 15, 23 (2022); https://doi.org/10.1016/j.jchromb.2022.123429
  121. H. Zhai, L. Sun, S. Fan, J. Wang, M. Cao, H. Ma, Q. Li and Y. Zhang, J. Future Foods, 3, 163 (2023); https://doi.org/10.1016/j.jfutfo.2022.12.007
  122. O.L. Knittelfelder, B.P. Weberhofer, T.O. Eichmann, S.D. Kohlwein and G.N. Rechberger, J. Chromatogr. B, 951-952, 119 (2014); https://doi.org/10.1016/j.jchromb.2014.01.011.
  123. Y. Liu, X. Zang, K. Feng, S. Liu, J. Zhang, Z. Lv, Y. Xin and M. Yu, Anal. Lett., 55, 879 (2022); https://doi.org/10.1080/00032719.2021.1970760
  124. M. Petrovic, M. Gros and D. Barcelo, J. Chromatogr. A, 1124, 68 (2006); https://doi.org/10.1016/j.chroma.2006.05.024
  125. M. Ibanez, C. Guerrero, J.V. Sancho and F. Hernandez, J. Chromatogr. A, 1216, 2529 (2009); https://doi.org/10.1016/j.chroma.2009.01.073
  126. R. Diaz, M. Ibanez, J.V. Sancho and F. Hernandez, J. Chromatogr. A, 1276, 47 (2013); https://doi.org/10.1016/j.chroma.2012.12.030
  127. G. Ding and X. Zhang, Environ. Sci. Technol., 43, 9287 (2009); https://doi.org/10.1021/es901821a
  128. X.G. Liu, J. Xu, F.S. Dong, Y.B. Li, W.C. Song and Y.Q. Zheng, Anal. Bioanal. Chem., 401, 1051 (2011); https://doi.org/10.1007/s00216-011-5148-3
  129. J. Wang, W. Chow, D. Leung and J. Chang, J. Agric. Food Chem., 60, 12088 (2012); https://doi.org/10.1021/jf303939s
  130. J. Wang, W. Chow and D. Leung, J. AOAC Int., 94, 1685 (2011); https://doi.org/10.5740/jaoacint.sgewang
  131. P. Venkateswarlu, K.R. Mohan, C. Kumar and K. Seshaiah, Food Chem., 105, 1760 (2007); https://doi.org/10.1016/j.foodchem.2007.04.074
  132. I. Ferrer, E.M. Thurman and A.R. Fernandez-Alba, Anal. Chem., 77, 2818 (2005); https://doi.org/10.1021/ac048458x
  133. I. Baranowska, J. Hejniak and S. Magiera, Chirality, 28, 147 (2016); https://doi.org/10.1002/chir.22559
  134. J. Yang, Y. Wang, L. Pan, N. Li, X. Lu, J. Guan, M. Cheng and F. Li, Talanta, 79, 1204 (2009); https://doi.org/10.1016/j.talanta.2009.03.036
  135. Q. Zhang, D. Wang, M. Zhang, Y. Zhao and Z. Yu, J. Chromatogr. B, 1041, 175 (2017); https://doi.org/10.1016/j.jchromb.2016.11.017
  136. H. Jin, T.D. Thangadurai, S.C. Jo, D. Jin, S. Cui and Y.I. Lee, Microchem. J., 103, 170 (2012); https://doi.org/10.1016/j.microc.2012.03.003
  137. J. Zhao, Y. Shin, Y. Jin, K.M. Jeong and J. Lee, J. Chromatogr. B, 1040, 199 (2017); https://doi.org/10.1016/j.jchromb.2016.11.016
  138. X. Pan, F. Dong, Z. Chen, J. Xu, X. Liu, X. Wu and Y. Zheng, J. Chromatogr. A, 1525, 87 (2017); https://doi.org/10.1016/j.chroma.2017.10.016
  139. H. Khan, World J. Pharm. Res., 8, 849 (2019).
  140. S. Kivrak, T. Göktürk, I. Kivrak, E. Kaya and E. Karababa, Food Sci. Technol., 39, 423 (2019); https://doi.org/10.1590/fst.32017
  141. T. Thomas, K. Petrie, J. Shim, K.M. Abildskov, C.L. Westhoff and S. Cremers, Therap. Drug Monit., 35, 844 (2013); https://doi.org/10.1097/FTD.0b013e31829a10fa
  142. M. Carlier, Int. J Antimicrob. Agents, 40, 416 (2012); https://doi.org/10.1016/j.ijantimicag.2012.06.022
  143. A.A.M. Stolker, P. Rutgers, E. Oosterink, J.J.P. Lasaroms, R.J.B. Peters, J.A. van Rhijn and M.W.F. Nielen, Anal. Bioanal. Chem., 391, 2309 (2008); https://doi.org/10.1007/s00216-008-2168-8
  144. E.A. Martis, R. Radhakrishnan and R.R. Badve, J. Appl. Pharm. Sci., 1, 2 (2011).
  145. P. Szymanski, M. Markowicz and E. Mikiciuk-Olasik, Int. J. Mol. Sci., 13, 427 (2012); https://doi.org/10.3390/ijms13010427
  146. J.W. Armstrong, Am. Biotech Lab., 17, 26 (1999).
  147. J.N. Kyranos, H. Cai, B. Zhang and W.K. Goetzinger, Curr. Opin. Drug Dis. Dev., 4, 719 (2001).
  148. A. Thomas and M. Thevis, Expert Rev. Proteom., 21, 27 (2024); https://doi.org/10.1080/14789450.2024.2305432
  149. F.T. Delbeke, K. Deventer, P.V. Eenoo and O.J. Pozo, LCGC North America, 26, 376 (2008).
  150. J.M. Colby, K.L. Thoren and K.L. Lynch, J. Anal. Toxicol., 42, 207 (2018); https://doi.org/10.1093/jat/bkx107
  151. D.R. Allen and B.C. McWhinney, Clin. Biochem. Rev., 40, 135 (2019); https:/doi.org/10.33176/AACB-19-00023
  152. M. Thevis, A. Thomas and W. Schanzer, Anal. Bioanal. Chem., 401, 405 (2011); https://doi.org/10.1007/s00216-011-4859-9
  153. M. Thevis, A. Thomas, V. Pop and W. Schänzer, J. Chromatogr. A, 1292, 38 (2013); https://doi.org/10.1016/j.chroma.2012.12.048
  154. Z. Wang, J. Lu, Y. Zhang, Y. Tian, H. Yuan and Y. Xu, Bioanalysis, 8, 1307 (2016); https://doi.org/10.4155/bio-2016-0030
  155. F. Badoud, E. Grata, L. Perrenoud, L. Avois, M. Saugy, S. Rudaz and J.-L. Veuthey, J. Chromatogr. A, 1216, 4423 (2009); https://doi.org/10.1016/j.chroma.2009.03.033
  156. F. Bodoud, E. Grata, L. Perrenoud, M. Saugy, S. Rudaz and J.-L. Veuthey, J. Chromatogr. A, 1217, 4109 (2010); https://doi.org/10.1016/j.chroma.2009.11.001
  157. F. Badoud, D. Guillarme, J. Boccard, E. Grata, M. Saugy, S. Rudaz and J.L. Veuthey, Forensic Sci. Int., 213, 49 (2011); https://doi.org/10.1016/j.forsciint.2011.07.024
  158. R. Ventura, M. Roig, N. Montfort, P. Saez, R. Berges and J. Segura, Eur. J. Mass Spectrom., 14, 191 (2008); https://doi.org/10.1255/ejms.920
  159. M. Mazzarino and F. Botre, Rapid Commun. Mass Spectrom., 20, 3465 (2006); https://doi.org/10.1002/rcm.2729
  160. K. Deventer, J.O. Pozo, P. Eenoo and F.T. Delbeke, Rapid Commun. Mass Spectrom., 21, 3015 (2007); https://doi.org/10.1002/rcm.3142
  161. R. Ventura, R. Ramírez, N. Monfort and J. Segura, J. Pharm. Biomed. Anal., 50, 886 (2009); https://doi.org/10.1016/j.jpba.2009.06.009
  162. J. Giron, K. Deventer, K. Roels and P.V. Eenoo, Anal. Chim. Acta, 721, 137 (2012); https://doi.org/10.1016/j.aca.2012.02.002
  163. A. Musenga and D.A. Cowan, J. Chromatogr. A, 1288, 82 (2013); https://doi.org/10.1016/j.chroma.2013.03.006
  164. S. Esposito, K. Deventer, G. TSjoen, A. Vantilborgh and P.V. Eenoo. Biomed. Chromatogr., 27, 240 (2013); https://doi.org/10.1002/bmc.2782
  165. I.M. Reddy, A. Beotra, S. Jain and S. Ahi, Indian J. Pharmacol., 41, 80 (2009).
  166. B.D. Ahrens, Y. Kucherova and A.W. Butch, Methods Mol. Biol., 1383, 247 (2016); https://doi.org/10.1007/978-1-4939-3252-8_26
  167. B.D. Ahrens, B. Starcevic and A.W. Butch, Methods Mol. Biol., 902, 115 (2012); https://doi.org/10.1007/978-1-61779-934-1_10
  168. M. Mazzarino, S. Turi and F. Botre, Anal. Bioanal. Chem., 390, 1389 (2008); https://doi.org/10.1007/s00216-007-1802-1
  169. G.J. Murray and J.P. Danaceau, J. Chromatogr. B, 877, 3857 (2009); https://doi.org/10.1016/j.jchromb.2009.09.036
  170. N. Monfort, L. Martínez, R. Bergés, J. Segura and R. Ventura, Drug Test. Anal., 7, 819 (2015); https://doi.org/10.1002/dta.1776
  171. I.L. Tsai, T.I. Weng, Y.J. Tseng, H.K. Tan, H.J. Sun and C.H. Kuo, J. Anal. Toxicol., 37, 642 (2013); https://doi.org/10.1093/jat/bkt083
  172. S. Broecker, S. Herre, B. Wüst, J. Zweigenbaum and F. Pragst, Anal. Bioanal. Chem., 400, 101 (2011); https://doi.org/10.1007/s00216-010-4450-9
  173. C. Noble, P. Dalsgaard, S. Johansen and K. Linnet, Drug Testing Anal., 10, 651 (2018); https://doi.org/10.1002/dta.2263
  174. J.O. Thorngren, F. Ostervall and M. Garle, J. Mass Spectrom., 43, 980 (2008); https://doi.org/10.1002/jms.1436
  175. M. Paul, J. Ippisch, C. Herrmann, S. Guber and W. Schultis, Anal. Bioanal. Chem., 406, 4425 (2014); https://doi.org/10.1007/s00216-014-7825-5
  176. F. Guan, C.E. Uboh, L.R. Soma, Y. You, Y. Liu and X. Li, J. Mass Spectrom., 45, 1270 (2010); https://doi.org/10.1002/jms.1816
  177. J. Wang, Z. Yang and J. Lechago, J. Biomed Chromatogr., 27, 1463 (2013); https://doi.org/10.1002/bmc.2945
  178. A Giorgetti, R Barone, G Pelletti, M Garagnani, J Pascali, B Haschimi and V Auwärter, Drug Testing Anal., 14, 202 (2022); https://doi.org/10.1002/dta.3170
  179. T. Langer, O. Salamin, R. Nicoli, S. Grabherr, T. Kuuranne and A. Musenga, Drug Testing Anal., 14, 1904 (2022); https://doi.org/10.1002/dta.3379
  180. O. Salamin, T. Langer, J. Saugy, M. Saugy, S. Grabherr, T. Kuuranne and R. Nicoli, Drug Testing Anal., 14, 1920 (2022); https://doi.org/10.1002/dta.3382
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