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Vol. 36 No. 1 (2024): Vol 36 Issue 1, 2024

Copyright (c) 2023 PARATHARAJ SENTHILKUMAR, Krishnan Radhakrishnan

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Effect of Substituent on the 13C NMR Chemical Shifts of Substituted 26-Member [2+2] Macrocyclic Compounds

https://doi.org/10.14233/ajchem.2024.30712
Krishnan Radhakrishnan
Department of Chemistry, Saraswathi Narayanan College of Arts and Science (Affiliated to Madurai Kamaraj University), Perungudi, Madurai-625022, Ind
https://orcid.org/0000-0002-1728-7410
Paratharaj Senthilkumar
CRD Department, RECEPS Limited, Visakha Pharmacity Limited, Visakhapatnam-531019, India
https://orcid.org/0009-0002-5196-1912

Corresponding Author(s) : Paratharaj Senthilkumar

senthilkumarparatharaj@gmail.com

Asian Journal of Chemistry, Vol. 36 No. 1 (2024): Vol 36 Issue 1, 2024

Abstract

A series of substituted symmetrical 14,15,34,35,94,95,114,115-octamethoxy-2,10-bis(4-methoxyphenyl)-4,8,12,16-tetraaza-1,3,9,11(1,2),6,14(1,4)-hexabenzenacyclohexadecaphane-4,7,12,15-tetraene compounds (macrocyclic compounds) have been prepared by condensation of various substituted benzaldehyde with 1,2-dimethoxy benzene followed by nitration, reduction and cyclization with terephthaldehyde.  Isolated substituted compounds were characterized by UV, IR, NMR and Mass spectrometric technics. Investigation of substituents effect and mode of transmission of electronic effects have been carried out by 13C NMR chemical shifts measurement and correlated it with LFER parameters in substituted macrocyclic compounds.

Keywords

Substituent effects Lynch correlations multiple regression analysis
Radhakrishnan, K., & Senthilkumar, P. (2023). Effect of Substituent on the 13C NMR Chemical Shifts of Substituted 26-Member [2+2] Macrocyclic Compounds. Asian Journal of Chemistry, 36(1), 177–183. https://doi.org/10.14233/ajchem.2024.30712
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