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Vol. 27 No. 12 (2015): Vol 27 Issue 12

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Synthesis, Spectroscopic Characterization, Antibacterial and Corrosion Inhibitory Activities of Some 3d-Metal Complexes of [(2-Pyrrole-2-carboxaldehyde)-3-isatin]bishydrazone

https://doi.org/10.14233/ajchem.2015.19346
S.S. Swathy
Department of Chemistry, Sree Narayana College, Varkala, Trivandrum-695 145, India
R. Biju
Department of Chemistry, Sree Narayana College, Varkala, Trivandrum-695 145, India
K. Mohanan
Department of Chemistry, University of Kerala, Kariavattom Campus, Trivandrum-695 581, India

Corresponding Author(s) : S.S. Swathy

rajendran.biju@gmail.com

Asian Journal of Chemistry, Vol. 27 No. 12 (2015): Vol 27 Issue 12

Abstract

A novel bishydrazone was synthesized by the condensation of isatin monohydrazone with pyrrole-2-carboxaldehyde, which formed a series of complexes with manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II). The ligand and the metal complexes were characterized on the basis of elemental analysis, molar conductance, magnetic moment, IR, UV-visible, 1H NMR, EPR and thermal analysis. Spectral studies revealed that the ligand acted as neutral bidentate, coordinating to the metal ion through the aldimine nitrogen and carbonyl oxygen atom of the isatin moiety. The low molar conductance values indicate that all complexes are non-electrolytes. Based on the spectral results and magnetic susceptibility measurements, suitable geometry was proposed for each metal complex. The EPR spectral data of copper(II) complex indicated that metal-ligand bond had considerable covalent character. The ligand and its nickel(II) complex were subjected to XRD studies. In vitro biological screening effects of the compounds were tested against the some selected bacteria by the agar disc diffusion method. The corrosion inhibitory activity of the ligand and its nickel(II) complex used in acid (H2SO4) media was examined by open circuit potential measurements.

Keywords

Hydrazone Spectral studies Cyclic voltammetry Antibacterial activity
Swathy, S., Biju, R., & Mohanan, K. (2015). Synthesis, Spectroscopic Characterization, Antibacterial and Corrosion Inhibitory Activities of Some 3d-Metal Complexes of [(2-Pyrrole-2-carboxaldehyde)-3-isatin]bishydrazone. Asian Journal of Chemistry, 27(12), 4679–4685. https://doi.org/10.14233/ajchem.2015.19346
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