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Vol. 27 No. 12 (2015): Vol 27 Issue 12

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Synthesis, Characterization and Antimicrobial Activity of Isomeric Pyridyl-Tetrazole Derivative Ligands and their Bivalent Metal Complexes

https://doi.org/10.14233/ajchem.2015.19144
B. Umamaheswara Rao
Department of Inorganic and Analytical Chemistry, Andhra University, Visakhapatnam-530 003, India
V. Krishna
Department of Chemistry, Malla Reddy Engineering College (Autonomous), Hyderabad-500 100, India
G. Nageswara Rao
Department of Inorganic and Analytical Chemistry, Andhra University, Visakhapatnam-530 003, India

Corresponding Author(s) : V. Krishna

krishnanitw2010@gmail.com; vaddadi_krishna@yahoo.com

Asian Journal of Chemistry, Vol. 27 No. 12 (2015): Vol 27 Issue 12

Abstract

Nickel(II) and zinc(II) complexes were synthesized from bidentate isomeric pyridyl tetrazole ligands such as 2-(1-vinyl-1H-tetrazol-5-yl)pyridine (L1), N,N-dimethyl-3-(5-(pyridin-2-yl)-1H-tetrazol-1-yl)propan-1-amine (L2), 2-(2-vinyl-2H-tetrazol-5-yl)pyridine (L3), N,N-dimethyl-3-(5-(pyridin-2-yl)-2H-tetrazol-2-yl)propan-1-amine (L4). All the complexes were characterized in the light of elemental analysis, FTIR, UV-visible and magnetic studies. The spectroscopic data suggested that, the ligands act as neutral and monobasic bidentate ligands and form octahedral complexes with general formula [M(L1-4)2Cl2] (M = Ni(II) and Zn(II). The isomeric pyridyl-tetrazole derivative ligands and their Ni(II) and Zn(II) complexes have also been screened for their antibacterial (Bacillus subtilis, Staphylococcus aureus, Proteus vulgaris) and antifungal activities (Aspergillus niger, Candida albicans) by MIC method.

Keywords

Isomeric pyridyl-tetrazole derivatives Nickel and Zinc complexes Antimicrobial activity
Umamaheswara Rao, B., Krishna, V., & Nageswara Rao, G. (2015). Synthesis, Characterization and Antimicrobial Activity of Isomeric Pyridyl-Tetrazole Derivative Ligands and their Bivalent Metal Complexes. Asian Journal of Chemistry, 27(12), 4405–4410. https://doi.org/10.14233/ajchem.2015.19144
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