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Vol. 29 No. 5 (2017): Vol 29 Issue 5

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Oxidation of Indole by Peroxomonosulfate in Acetic Acid Medium: A Kinetic and Antibacterial Study

https://doi.org/10.14233/ajchem.2017.20485%20
K. Muniyappan
R&D Centre, Bharathiar University, Coimbatore-641 046, India
G. Chandramohan
Principal & Research Advisor, Jairams Arts and Science College, Karur-639 003, India

Corresponding Author(s) : K. Muniyappan

muni.kavery@gmail.com

Asian Journal of Chemistry, Vol. 29 No. 5 (2017): Vol 29 Issue 5

Abstract

Kinetics of oxidation of indole by peroxomonosulfate (PMS) has been studied at 283 to 308 K in aqueous acetic acid medium. The reaction follows a total second order, first order each with respect to [Indole] and [PMS]. The rate of the reaction was not affected by added [H+]. Variation of ionic strength (μ) had no influence on the rate. There was no solvent effect when increase the percentage of acetic acid. There was no polymerization occur in reaction pathway. Thermodynamic parameters such as free energy of activation (DE#), enthalpy of activation (DH#) and entropy of activation (DS#) have been evaluated. The most plausible mechanism scheme proposed by these kinetic observations and the antibacterial activity was carried out by agar diffusion method.

Keywords

Kinetics Mechanism Oxidation Indole Acetic acid Peroxomonosulfate
Muniyappan, K., & Chandramohan, G. (2017). Oxidation of Indole by Peroxomonosulfate in Acetic Acid Medium: A Kinetic and Antibacterial Study. Asian Journal of Chemistry, 29(5), 1155–1160. https://doi.org/10.14233/ajchem.2017.20485
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