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Isolation and Antioxidant Activity of Caffeic Acid from Roots of Bryophyllum pinnatum (Lam.) Kurz.
Corresponding Author(s) : Abhishek Sharma
Asian Journal of Chemistry,
Vol. 29 No. 2 (2017): Vol 29 Issue 2
Abstract
Bryophyllum pinnatum (Lam.) Kurz. (Crassulaceae) is a perennial shrub, which possess bioactive phytoconstituents viz. terpenoids, phenolic compounds, flavonoid, anthraquinone, saponin and known to cure diabetes, cancer and act as anti-inflammatory, antiulcer, antihyperlipidemia. In the present study, isolation and antioxidant activity of caffeic acid from roots of Bryophyllum pinnatum (Lam.) Kurz. was carried out. Caffeic acid was characterized by TLC, FTIR and was elucidated by 1H NMR and 13C NMR technique. DPPH radical scavenging power of isolated caffeic acid showed IC50 value 66.58 ± 0.49 μg/mL in comparison to aqueous extract of root (139.52 ± 2.62 μg/mL).
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- D. Schuppan, J.D. Jia, B. Brinkhaus and E.G. Hahn, Hepatology, 30, 1099 (1999).
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- T.K. Mohanta, J.K. Patra, S.K. Rath, D.K. Pal and H.N. Thatoi, Sci. Res. Essays, 2, 486 (2007).
- A. Sofowara, Medicinal Plants and Traditional Medicine in Africa, Spectrum Books Ltd., Ibadan, Nigeria (1993).
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- A. Braca, C. Sortino, M. Politi, I. Morelli and J. Mendez, J. Ethnopharmacol., 79, 379 (2002).
- P.-D. Duh, Y.-Y. Tu and G.-C. Yen, Lebens. Wissen. Technol., 32, 269 (1999).
- I.I. Koleva, T.A. van Beek, J.P.H. Linssen, A. Groot and L.N. Evstatieva, Phytochem. Anal., 13, 8 (2002).
- P.K. Suresh, S. Sucheta, V.D. Sudarshana, P. Selvamani and S. Latha, Afr. J. Biotechnol., 7, 1826 (2008).
- G.E. Trease and W.C. Evans, Pharmacognosy, Brailliar Tiridel Can Macmillan Publishers, edn 11, pp. 60-75 (1989).
- K. Shimomura, K. Yoshimatsu, M. Jaziri and K. Ishimaru, in eds.: K. Watanabe and E.R.G. Pehu, Traditional Medicinal Plant Genetic Resources and Biotechnology Applications, In: Plant Biotechnology and Plant Genetic Resources for Sustainability and Productivity, R.G. Landes Company and Academic Press Inc., Austin, Texas, pp. 209-225 (1997).
References
D. Schuppan, J.D. Jia, B. Brinkhaus and E.G. Hahn, Hepatology, 30, 1099 (1999).
I. Aibinu, T. Adenikpekun, T. Adelowotan, T. Ogunsanya and T. Odugbemi, African J. Trad. Comp. Alt. Med., 4, 185 (2007).
P.A. Akah and A.I. Nwambie, J. Ethnopharmacol., 42, 179 (1994).
L.V. Roze, A. Chanda and J.E. Linz, Fungal Genet. Biol., 48, 35 (2011).
O. Erturk, H. Kati, N. Yayli and Z. Demirbag, Turk. J. Biol., 30, 17 (2006).
T.K. Mohanta, J.K. Patra, S.K. Rath, D.K. Pal and H.N. Thatoi, Sci. Res. Essays, 2, 486 (2007).
A. Sofowara, Medicinal Plants and Traditional Medicine in Africa, Spectrum Books Ltd., Ibadan, Nigeria (1993).
A. Kamboj and A.K. Saluja, Pharmacogn. Rev., 3, 64 (2009).
A. Braca, C. Sortino, M. Politi, I. Morelli and J. Mendez, J. Ethnopharmacol., 79, 379 (2002).
P.-D. Duh, Y.-Y. Tu and G.-C. Yen, Lebens. Wissen. Technol., 32, 269 (1999).
I.I. Koleva, T.A. van Beek, J.P.H. Linssen, A. Groot and L.N. Evstatieva, Phytochem. Anal., 13, 8 (2002).
P.K. Suresh, S. Sucheta, V.D. Sudarshana, P. Selvamani and S. Latha, Afr. J. Biotechnol., 7, 1826 (2008).
G.E. Trease and W.C. Evans, Pharmacognosy, Brailliar Tiridel Can Macmillan Publishers, edn 11, pp. 60-75 (1989).
K. Shimomura, K. Yoshimatsu, M. Jaziri and K. Ishimaru, in eds.: K. Watanabe and E.R.G. Pehu, Traditional Medicinal Plant Genetic Resources and Biotechnology Applications, In: Plant Biotechnology and Plant Genetic Resources for Sustainability and Productivity, R.G. Landes Company and Academic Press Inc., Austin, Texas, pp. 209-225 (1997).