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Synthesis, Characterization and Antimicrobial Screening of Mn(II), Ni(II) and Cu(II) Complexes of 3,4,5-Trihydroxy benzoic acid[1-(pyridyl)ethylidene]hydrazone
Corresponding Author(s) : J. Rosaline Ezhilarasi
Asian Journal of Chemistry,
Vol. 29 No. 12 (2017): Vol 29 Issue 12
Abstract
In the present study, synthesis of Mn(II), Ni(II) and Cu(II) complexes of 3,4,5-trihydroxy benzoic acid[1-(pyridyl)ethylidene]-hydrazone is reported. The synthesized complexes were characterized by IR, UV-visible, 1H NMR, mass spectroscopy, TGA-DTA, XRD, elemental analysis and conductivity measurements. The spectral studies indicate that the synthesized complexes possess octahedral geometry. These complexes also exhibited the antimicrobial activities.
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References
H. Schiff, Anal. Chem. Pharm., 3(Suppl.), 241 (1864).
N. Ahmed, M. Riaz, A. Ahmed and M. Bhagat, Int. J. Inorg. Chem., Article ID 607178 (2015); https://doi.org/10.1155/2015/607178.
G. Verma, A. Marella, M. Shaquiquzzaman, M. Akhtar, M.R. Ali and M.M. Alam, J. Pharm. Bioallied Sci., 6, 69 (2014); https://doi.org/10.4103/0975-7406.129170.
L. Popiolek, Med. Chem. Res., 26, 287 (2017); https://doi.org/10.1007/s00044-016-1756-y.
R. Narang, B. Narasimhan and S. Sharma,Curr. Med. Chem., 19, 569 (2012); https://doi.org/10.2174/092986712798918789.
H. Sahebalzamani, F. Salimi and E. Dornapour, J. Chem., Article ID 187974 (2013); https://doi.org/10.1155/2013/187974.
A.A.R. Despaigne, L.F. Vieira, I.C. Mendes, F.B. Costa, N.L. Speziali and H. Beraldo, J. Braz. Chem. Soc., 21, 1247 (2010); https://doi.org/10.1590/S0103-50532010000700012.
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H.H.A. Rassem and A.H. Nour, Int. J. Eng. Sci. Res. Technol., 4, 1036 (2015).
A. Pawaiya, P. Pawaiya and S. Rajput, Int. J. Curr. Res., 6, 8423 (2014).
I. Babahan, E.P. Coban and H. Biyik, Maejo Int. J. Sci. Technol., 7, 26 (2013).
E. Pahontu, D.-C. Ilies, S. Shova, C. Paraschivescu, M. Badea,A. Gulea and T. Rosu, Molecules, 20, 5771 (2015); https://doi.org/10.3390/molecules20045771.
J. Gunjan and D. Awadh, Int. Res. J. Pharm., 2, 110 (2011).
T. Govindasami, A. Pandey, N. Palanivelu and A. Pandey, Int. J. Org. Chem., 1, 71 (2011); https://doi.org/10.4236/ijoc.2011.13012.
N.H. Al-Sha’alan, Molecules, 12, 1080 (2007); https://doi.org/10.3390/12051080.
S. Rollas and S.G. Kücükgüzel, Molecules, 12, 1910 (2007); https://doi.org/10.3390/12081910.
N. Singh, R. Ranjana, M. Kumari and B. kumar, Int. J. Pharm. Clin. Res., 8, 162 (2016).
M. Singh and N. Raghav, Int. J. Pharm. Pharm. Sci., 3, 26 (2011).
R.M. Mohareb, D.H. Fleita and O.K. Sakka, Molecules, 16, 16 (2010); https://doi.org/10.3390/molecules16010016.
G. Naganagowda, R. Meijboom and A. Petsom, Adv. Chem., Article ID 921857 (2014); https://doi.org/10.1155/2014/921857.
Y. Toledano-Magaña, J. García-Ramos, M. Navarro-Olivarria, M. FloresAlamo, M. Manzanera-Estrada, L.Ortiz-Frade, R. Galindo-Murillo, L. Ruiz-Azuara, R. Meléndrez-Luevano and B. Cabrera-Vivas, Molecules, 20, 9929 (2015); https://doi.org/10.3390/molecules20069929.
R.M. Ahmed, E.I. Yousif, H.A. Hasan and M.J. Al-Jeboori, Sci. World J., Article ID 289805 (2013); https://doi.org/10.1155/2013/289805.
J.N. Asegbeloyin, O.T. Ujam, E.C. Okafor, I. Babahan, E.P. Coban, A. Ozmen and H. Biyik, Bioinorg. Chem. Appl., 2014, 1 (2014); https://doi.org/10.1155/2014/718175.
Z. Cui, H. Su, J. Jiang, X. Yang and Y. Nishida, Int. J. Mol. Sci., 15, 6741 (2014); https://doi.org/10.3390/ijms15046741.
W.W. Wardakhan and E.M. Samir, J. Chil. Chem. Soc., 57, 1118 (2012); https://doi.org/10.4067/S0717-97072012000200013.
S. Arunkumar, K. Ilango, R.S. Manikandan, N. Ramalakshmi and M. Sudha, Int. J. Chemtech Res., 4, 1094 (2009).
A.A. Alhadi, S.A. Shaker, N. Suleiman, G.W.A. Yehye and H.M. Ali, J. Chil. Chem. Soc., 57, 1283 (2012); https://doi.org/10.4067/S0717-97072012000300018.