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Vol. 29 No. 10 (2017): Vol 29 Issue 10

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In vitro Antioxidant Potential of Methanolic Extract of Symplocos racemosa Roxb.

https://doi.org/10.14233/ajchem.2017.20747
Dattatreya Kar
Centre for Biotechnology, Siksha "O" Anusandhan University, Kalinga Nagar, Ghatikia, Bhubaneswar-751 003, India
Manoj Kumar Panda
Centre for Biotechnology, Siksha "O" Anusandhan University, Kalinga Nagar, Ghatikia, Bhubaneswar-751 003, India

Corresponding Author(s) : Manoj Kumar Panda

manojpanda@soauniversity.ac.in

Asian Journal of Chemistry, Vol. 29 No. 10 (2017): Vol 29 Issue 10

Abstract

Many hazardous diseases are caused by free radicals accumulation. A number of investigations are focusing to find out the plant oriented natural antioxidant moieties. The basic aim of this research was to investigate the antioxidant potential of different plant parts of the crude methanolic extract of Symplocos racemosa. Symplocos racemosa (Symplocaceae) commonly known as “Lodhra” and is useful in diarrhoea, dysentery, eye diseases, fever, ulcer, scorpion sting, diabetes and liver disorders. Here the bark, leaf and root were screened for in vitro antioxidant activity study using DPPH, nitric oxide, hydroxyl radical and ABTS assay methods. Both ascorbic acid and rutin are used as a standard. The results of the study indicated that the methanolic extract of Symplocos racemosa showed potent antioxidant activity in ABTS assay method than other methods. These research investigations revealed that Symplocos racemosa is a potent source of natural antioxidants. Hence the plant can be used for management of different stress and anxiety related ailments.

Keywords

Symplocos racemosa Methanolic extract Antioxidant activity
Kar, D., & Panda, M. K. (2017). In vitro Antioxidant Potential of Methanolic Extract of Symplocos racemosa Roxb. Asian Journal of Chemistry, 29(10), 2271–2274. https://doi.org/10.14233/ajchem.2017.20747
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References
  1. O.A. Aiyegoro and A.I. Okoh, BMC Complement. Altern. Med., 10, 21 (2010); https://doi.org/10.1186/1472-6882-10-21.
  2. D. Harman, Ann. N. Y. Acad. Sci., 854, 1 (1998); https://doi.org/10.1111/j.1749-6632.1998.tb09886.x.
  3. M.R. Khan, W. Rizvi, G.N. Khan, R.A. Khan and S. Shaheen, J. Ethnopharmacol., 122, 91 (2009); https://doi.org/10.1016/j.jep.2008.12.006.
  4. R.A. Khan, M.R. Khan and S. Sahreen, J. Ethnopharmacol., 128, 452 (2010); https://doi.org/10.1016/j.jep.2010.01.026.
  5. A. Sofowora, E. Ogunbodede and A. Onayade, Afr. J. Tradit. Complement. Altern. Med., 10, 210 (2013).
  6. R.A. Khan, M.R. Khan, S. Sahreen and J. Bokhari, Afr. J. Biotechnol., 9, 3883 (2010); https://doi.org/10.5897/AJB2010.000-3261.
  7. M.R. Khan, J. Haroon, R.A. Khan, J. Bokhari and U. Rashid, J. Med. Plants Res., 5, 2514 (2011).
  8. R.A. Khan, M.R. Khan, S. Sahreen, S. Jan, J. Bokhari and U. Rashid, Afr. J. Biotechnol., 10, 5377 (2011); https://doi.org/10.5897/AJB10.2194.
  9. Y.Z. Cai, M. Sun and H. Corke, J. Agric. Food Chem., 51, 2288 (2003); https://doi.org/10.1021/jf030045u.
  10. S. Sahreen, M.R. Khan and R.A. Khan, Food Chem., 122, 1205 (2010); https://doi.org/10.1016/j.foodchem.2010.03.120.
  11. S. Sahreen, M.R. Khan and R.A. Khan, BMC Complement. Altern. Med., 11, 48 (2011); https://doi.org/10.1186/1472-6882-11-48.
  12. E. Bursal, E. Koksal, I. Gulçin, G. Bilsel and A.C. Goren, Food Res. Int., 51, 66 (2013); https://doi.org/10.1016/j.foodres.2012.11.022.
  13. I. Gulcin, Arch. Toxicol., 86, 345 (2012); https://doi.org/10.1007/s00204-011-0774-2.
  14. P.C. Sharma, Data Base on Medicinal Plants used in Ayurveda, Central Council for Research in Ayurveda and Siddha, vol. 5, pp. 164-168 (2002).
  15. K.R. Nadkarni, Indian Material Medica, Popular Prakashan, Bombay, vol. 2, p. 1186 (2002).
  16. G.S. Kumar, K.N. Jayaveera, C.K. Ashok Kumar, P.S. Umachigi, B.M. Vrushabendra and D.V. Kishore, Trop. J. Pharm. Res., 6, 717 (2007).
  17. B.P. Raval, M.P. Suthar and R. Patel, Int. J. Pharm. Res., 1, 31 (2009).
  18. K.K. Bhutani, A.N. Jadhav and V. Kalia, J. Ethnopharmacol., 94, 197 (2004); https://doi.org/10.1016/j.jep.2004.04.022.
  19. N.R. Krishnaswamy, Chemistry of Natural Products-A Laboratory Hand Book, University Press (India) Pvt. Ltd., Hyderabad, India, p. 123 (2003).
  20. W. Brand-Williams, M.E. Cuvelier and C. Berset, LWT-Food Sci. Technol., 28, 25 (1995); https://doi.org/10.1016/S0023-6438(95)80008-5.
  21. T.A. Koleva II, T.A. van Beek, J.P.H. Linssen, A. Groot and L.N. Evstatieva, Phytochem. Anal., 13, 8 (2002); https://doi.org/10.1002/pca.611.
  22. R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. Rice-Evans, Free Radic. Biol. Med., 26, 1231 (1999); https://doi.org/10.1016/S0891-5849(98)00315-3.
  23. B. Halliwell and J.M.C. Gutteridge, FEBS Lett., 128, 347 (1981); https://doi.org/10.1016/0014-5793(81)80114-7.
  24. M. Umamaheswari and T.K. Chatterjee, Afr. J. Tradit. Compl. Altern. Med., 5, 61 (2008).
  25. H.Y. Kil, E.S. Seong, B.K. Ghimire, I.M. Chung, S.S. Kwon, E.J. Goh, K. Hoe, M.J. Kim, J.D. Lim, D. Lee and C.Y. Yu, Food. Chem., 115, 1234 (2009); https://doi.org/10.1016/j.foodchem.2009.01.032.
  26. H.O. Vongtau, J. Abbah, B.A. Chindo, O. Mosugu, A.O. Salawu, H.O. Kwanashie and K.S. Gamaniel, J. Pharm. Biol., 43, 113 (2005); https://doi.org/10.1080/13880200590919401.
  27. K.A. Oluyemi, U.C. Okwuonu, D.G. Baxter and T.O. Oyesola, Int. J. Morphol., 25, 609 (2007); https://doi.org/10.4067/S0717-95022007000300023.
  28. R. Tambe, M. Kulkarni and K. Bhise, J. Pharmacogn. Phytochem., 2, 45 (2013).
  29. E.U. Etuk, B.M. Agaie, M.J. Ladan and I. Garba, Afr. J. Pharm. Pharmacol., 3, 151 (2009).
  30. R.J. Ruch, S.J. Cheng and J.E. Klaunig, Carcinogenesis, 10, 1003 (1989); https://doi.org/10.1093/carcin/10.6.1003.
  31. M.L.R. Motar, G. Thomas and J.M. Barbosa Fillo, J. Ethnopharmacol., 95, 139 (1985).
  32. D.S. Ogunleye and S.F. Ibitoye, Trop. J. Pharm. Res., 2, 239 (2003).
  33. R.C. Decorti and W.A. Creacy, eds.: W.I. Taylor and N.R. Fanworths, The Cantharadus Alkaloids, Marcel Dekker, New York, p. 237 (1975).
  34. P.X. Nunes, F.S. Silva, J.R.Guedes da S. Almeida, J.T. de Lima, L.A. de A. Ribeiro, L.J. Quintans Jr. and J.M.B. Filho, ed.: V. Rao, Biological Oxidations and Antioxidant Activity of Natural Products, In: Phytochemicals as Nutraceuticals-Global Approaches to Their Role in Nutrition and Health, InTech, Chap. 1, (2012).
  35. I. Gulcin, M. Oktay, E. Kirecci and O.I. Kufrevioglu, Food Chem., 83, 371 (2003); https://doi.org/10.1016/S0308-8146(03)00098-0.
  36. M. Vijayabaskaran, G. Babu, N. Venkateswaramurthy, R.K. Yuvaraja, B.P. Sivakumar and B. Jayakar, Int. J. Pharm. Technol., 2, 320 (2010).
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