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Vol. 29 No. 10 (2017): Vol 29 Issue 10

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Identification of Atropine and Scopolamine from Datura L. Plant and Market Samples by GC-MS

https://doi.org/10.14233/ajchem.2017.20619
D. Nandini
Research and Development Centre, Bharatiar University, Coimbatore-641 046, India
B.S. Ravikumar
Department of Botany, A.V.K. College for Women, Hassan-573 201, India
S.R. Amaraneni
Department of Chemistry, Dayananda Sagar University, Bengaluru-560 068, India

Corresponding Author(s) : D. Nandini

nandinidholepat@gmail.com

Asian Journal of Chemistry, Vol. 29 No. 10 (2017): Vol 29 Issue 10

Abstract

Datura plant which generally grows as weed, is also used for medicinal purposes. The plant is narcotic and used to treat skin diseases and rheumatic pain. Atropine and scopolamine are the main alkaloids in the plant. Atropine is antimuscuranic whereas, scopolamine affects central nervous system. In the present study, the presence of atropine and scopolamine were verified in leaves and seeds of Datura stramonium and D. metel. Argemone mexicana which is another weed is also generally identified as ‘Datturi’ and a popular chewing product called ‘pan masala’ were also subjected to GC-MS analysis. Hexane extracts did not show the presence of atropine and scopolamine. However, ethyl acetate and methanol extracts of both species of Datura elucidated the presence of alkaloids. Argemone mexicana and ‘Pan masala’ did not show the presence of atropine and scopolamine. This confirms that Argemone mexicana, is not an alternate to Datura and commercial ‘Pan masala’ does not contains the alkaloids.

Keywords

Datura Argemone mexicana Pan masala Atropine Scopolamine GC-MS
Nandini, D., Ravikumar, B., & Amaraneni, S. (2017). Identification of Atropine and Scopolamine from Datura L. Plant and Market Samples by GC-MS. Asian Journal of Chemistry, 29(10), 2116–2118. https://doi.org/10.14233/ajchem.2017.20619
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