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Vol. 26 No. 23 (2014)

Copyright (c) 2014 Muhammad Iqbal1, Rubina Iqbal1, Muhammad Bilal2, Muhammad Akram3, Imam Bakhsh Baloch1, Musa Kaleem Baloch1

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Antimicrobial Activities of Monoesters of Succinic Acid

https://doi.org/10.14233/ajchem.2014.16959
Muhammad Iqbal1
1Department of Chemistry, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 2Gomal College of Veterinary Sciences, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 3Medicinal Botanic Centre, PCSIR Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan *Corresponding author: Fax: +92 966 750255; Tel: +92 966 750424-429; E-mail: miqbal_44@yahoo.com
Rubina Iqbal1
1Department of Chemistry, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 2Gomal College of Veterinary Sciences, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 3Medicinal Botanic Centre, PCSIR Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan *Corresponding author: Fax: +92 966 750255; Tel: +92 966 750424-429; E-mail: miqbal_44@yahoo.com
Muhammad Bilal2
1Department of Chemistry, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 2Gomal College of Veterinary Sciences, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 3Medicinal Botanic Centre, PCSIR Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan *Corresponding author: Fax: +92 966 750255; Tel: +92 966 750424-429; E-mail: miqbal_44@yahoo.com
Muhammad Akram3
1Department of Chemistry, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 2Gomal College of Veterinary Sciences, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 3Medicinal Botanic Centre, PCSIR Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan *Corresponding author: Fax: +92 966 750255; Tel: +92 966 750424-429; E-mail: miqbal_44@yahoo.com
Imam Bakhsh Baloch1
1Department of Chemistry, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 2Gomal College of Veterinary Sciences, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 3Medicinal Botanic Centre, PCSIR Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan *Corresponding author: Fax: +92 966 750255; Tel: +92 966 750424-429; E-mail: miqbal_44@yahoo.com
Musa Kaleem Baloch1
1Department of Chemistry, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 2Gomal College of Veterinary Sciences, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan 3Medicinal Botanic Centre, PCSIR Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan *Corresponding author: Fax: +92 966 750255; Tel: +92 966 750424-429; E-mail: miqbal_44@yahoo.com

Corresponding Author(s) : Muhammad Iqbal1

Asian Journal of Chemistry, Vol. 26 No. 23 (2014)

Abstract

Present study describes the antimicrobial activities of the di- and tri-substituted benzyl monoesters (1-27) derived from succinic anhydride. The monoesters were screened against two fungi (C. albicans and A. niger) and two bacteria (E. coli, P. mirabilis) strains. All the compounds displayed bioactivity against screened microbes. However, the activities were dependent on the nature of the substituents. Zones of inhibition and minimum inhibitory concentrations (MICs) of the monoesters are reported. Chloramphenicol and ketoconazole were used as standard antibacterial and antifungal drugs respectively.

Keywords

Succinic anhydride Benzyl alcohols Monoesters of succinic acid.
Iqbal1, M., Iqbal1, R., Bilal2, M., Akram3, M., Bakhsh Baloch1, I., & Kaleem Baloch1, M. (2014). Antimicrobial Activities of Monoesters of Succinic Acid. Asian Journal of Chemistry, 26(23), 8025–8028. https://doi.org/10.14233/ajchem.2014.16959
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