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Vol. 26 No. 20 (2014)

Copyright (c) 2014 Zülbiye Önal*, Ayhan Özalp, Ilhan Özer Ilhan, Güzin Aslan

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Synthesis and Characterization of Diazenyl-1,3-diphenylpropane-1,3-dione and 5-[Hydroxy(phenyl)methyl]-4-phenylpyrimidine Derivatives

https://doi.org/10.14233/ajchem.2014.17461
Zülbiye Önal*
Department of Chemistry, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey *Corresponding author: Fax: +90 352 4374931 E-mail: zulbiye@erciyes.edu.tr
Ayhan Özalp
Department of Chemistry, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey *Corresponding author: Fax: +90 352 4374931 E-mail: zulbiye@erciyes.edu.tr
Ilhan Özer Ilhan
Department of Chemistry, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey *Corresponding author: Fax: +90 352 4374931 E-mail: zulbiye@erciyes.edu.tr
Güzin Aslan
Department of Chemistry, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey *Corresponding author: Fax: +90 352 4374931 E-mail: zulbiye@erciyes.edu.tr

Corresponding Author(s) : Zülbiye Önal*

Asian Journal of Chemistry, Vol. 26 No. 20 (2014)

Abstract

Various novel diazenyl-1,3-diphenylpropane-1,3-dione derivatives (2a-f) were prepared by the condensation of the diazonium salts of N-aminopyrimidine derivatives with b-diketones. Also, a series of novel 5-[hydroxy(phenyl)methyl]-4-phenylpyrimidine derivatives (3a-f) were synthesized from the reduction reactions of N-aminopyrimidine derivatives with NaBH4. The structures of all the new synthesized compounds were characterized by the 13C-NMR, 1H-NMR and IR spectroscopic data and elemental analysis.

Keywords

N-Aminopyrimidines Diazonium salts b-Diketones Reduction Reactions.
Önal*, Z., Özalp, A., Özer Ilhan, I., & Aslan, G. (2014). Synthesis and Characterization of Diazenyl-1,3-diphenylpropane-1,3-dione and 5-[Hydroxy(phenyl)methyl]-4-phenylpyrimidine Derivatives. Asian Journal of Chemistry, 26(20), 6931–6934. https://doi.org/10.14233/ajchem.2014.17461
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References
  1. A.S. Galabov, E. Velichkova, A. Karparov, D. Sidzhakova, D. Danchev and N. Chakova, Arzneimittelforschung, 34, 9 (1984).
  2. N. Azas, P. Rathelot, S. Djekou, F. Delmas, A. Gellis, C. Di Giorgio, P. Vanelle and P. Timon-David, Farmaco, 58, 1263 (2003).
  3. P.F. Juby, T.W. Hudyma, M. Brown, J.M. Essery and R.A. Partyka, J. Med. Chem., 22, 263 (1979).
  4. P.F. Juby, T.W. Hudyma, M. Brown, J.M. Essery and R.A. Partyka, J. Med. Chem., 25, 1145 (1982).
  5. S. Raic-Malic, D. Svedruzic, T. Gazivoda, A. Marunovic, A. Hergold-Brundic, A. Nagl, J. Balzarini, E. De Clercq and M. Mintas, J. Med. Chem., 43, 4806 (2000).
  6. B. Altural, Y. Akçamur, E. Saripinar, I. Yildirim and G. Kollenz, Monatsh. Chem., 120, 1015 (1989).
  7. Y. Akçamur, B. Altural, E. Saripinar, G. Kollenz, O. Kappe, E.M. Peters, E.-M. Peters and H.-G. Von Schnering, J. Heterocycl. Chem., 25, 1419 (1988).
  8. E. Saripinar, Y. Guzel, Z. Onal, I.O. Ilhan and Y. Akcamur, J. Chem. Soc. Pak., 22, 308 (2000).
  9. E. Saripinar, Ç. Yilmaz, D. Ünal, I. Özer Ilhan, N. Yazir and Y. Akçamur, Heterocycles, 68, 2045 (2006).
  10. I. Yildirim and I. Koca, Kuwait J. Sci. Eng, 32, 49 (2005).
  11. Z. Önal and I. Yildirim, Heterocycl. Commun., 13, 113 (2007).
  12. Z. Önal, I. Yildirim, F. Kandemirli and T. Arslan, Struct. Chem., 21, 809 (2010).
  13. Z. Önal, E. Saripinar and I.Ö. Ilhan, J. Heterocycl. Chem., 38, 397 (2001).
  14. Z. Önal and B. Altural, Turk. J. Chem., 23, 401 (1999).
  15. Z. Önal and A.C. Daylan, Asian J. Chem., 19, 2647 (2007).
  16. Z. Önal, N. Atli and Ö.I. Ilhan, Heterocycl. Commun., 15, 385 (2009).
  17. Z. Önal, H. Ceran and E. Sahin, Heterocycl. Commun., 14, 245 (2008).
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