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Vol. 28 No. 8 (2016): Vol 28 Issue 8

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Synthesis and Characterization of Novel Pyridine Associated 1,2,4-Triazolo-1,3,4-thiadiazines

https://doi.org/10.14233/ajchem.2016.19795
Sudugu Ramakrishna Reddy
Department of Chemistry, University College of Engineering, Osmania University, Hyderabad-500 007, India
Ch. Venkata Ramana Reddy
Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad-500 085, India
B. Satyanarayana
Department of Chemistry, University College of Engineering, Osmania University, Hyderabad-500 007, India

Corresponding Author(s) : B. Satyanarayana

ramkrishnajntu@gmail.com

Asian Journal of Chemistry, Vol. 28 No. 8 (2016): Vol 28 Issue 8

Abstract

A series of novel 3-(1-methyl-1H-pyrazol-4-yl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadaizine and its derivatives (8a-f) were synthesized by using 1-methyl-1H-pyrazole-4-carboxylic acid (3) as starting material and by involving 1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester (4), 1-methyl-1H-pyrazole-4-carboxylic acid hydrazide (5), 5-(1-methyl-1H-pyrazol-4-yl)-[1,3,4]oxadiazole-2-thiol (6) and 4-amino-5-(1-methyl-1H-pyrazol-4-yl)-4H-[1,2,4]triazole-3-thiol (7) as intermediate.

Keywords

Pyrazoles Thiadiazoles Heterocyclic chemistry
Reddy, S. R., Ramana Reddy, C. V., & Satyanarayana, B. (2016). Synthesis and Characterization of Novel Pyridine Associated 1,2,4-Triazolo-1,3,4-thiadiazines. Asian Journal of Chemistry, 28(8), 1708–1712. https://doi.org/10.14233/ajchem.2016.19795
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