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Vol. 28 No. 2 (2016): Vol 28 Issue 2

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Enzymatic Synthesis of Citronellyl Palmitate in Organic Media: Process Optimization and Kinetic Evaluation

https://doi.org/10.14233/ajchem.2016.19276
Ayoub Rashid
Department of Chemistry, Government College University, Lahore 54000, Pakistan
Naeem Akhtar Virk
Department of Chemistry, Government College University, Lahore 54000, Pakistan
Abdul Rehman Sadiq Butt
Department of Chemistry, Government College University, Lahore 54000, Pakistan
Ahmad Adnan
Department of Chemistry, Government College University, Lahore 54000, Pakistan
Muhammad Pervaiz
Department of Chemistry, Government College University, Lahore 54000, Pakistan
Muhammad Arshad Raza
Department of Chemistry, Government College University, Lahore 54000, Pakistan
Quratulain Syed
PCSIR Laboratories, Lahore, Pakistan

Corresponding Author(s) : Ahmad Adnan

mpbhatti@gmail.com

Asian Journal of Chemistry, Vol. 28 No. 2 (2016): Vol 28 Issue 2

Abstract

Kinetics of citronellyl palmitate ester formation from citronellol-palmitic acid was studied by using immobilized lipase Novozym 435 Candida antarctica. Lipase immobilized onto macroporous acrylic resin gave the best results. Different parameters like reaction medium, temperature, substrate concentration were optimized for the enzymatic synthesis of citronellyl palmitate. The optimum temperature was 30 °C, optimum molar ratio of alcohol to acid was 1:1. The best solvent for maximum esterification was n-hexane. At higher concentration of alcohol enzyme inhibition took place.

Keywords

Lipase Novozyme 435 by Candida antarctica Citronellol palmitic acid n-Hexane
Rashid, A., Virk, N. A., Sadiq Butt, A. R., Adnan, A., Pervaiz, M., Raza, M. A., & Syed, Q. (2015). Enzymatic Synthesis of Citronellyl Palmitate in Organic Media: Process Optimization and Kinetic Evaluation. Asian Journal of Chemistry, 28(2), 298–300. https://doi.org/10.14233/ajchem.2016.19276
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