Isolation and Identification of Flavonoid Compound from Nutmeg Leaves (Myristica fragrans Houtt)

Binawati Ginting; Lamek Marpaung; Tonel Barus; Partomuan Simanjuntak3

doi:10.14233/ajchem.2016.19342

Issue

Vol. 28 No. 1 (2016): Vol 28 Issue 1

Issue Published : October 5, 2015

This work is licensed under a Creative Commons Attribution 4.0 International License.

Isolation and Identification of Flavonoid Compound from Nutmeg Leaves (Myristica fragrans Houtt)

https://doi.org/10.14233/ajchem.2016.19342

Binawati Ginting

Faculty of Mathematics and Natural Sciences, Syiah Kuala University, Jl Tanoh Abee, Kopelma Unsyiah, Banda Aceh, Indonesia; Faculty of Mathematics and Natural Sciences, Sumatra Utara University, Jalan Padang Bulan, Medan, Indonesia

Lamek Marpaung

Faculty of Mathematics and Natural Sciences, Sumatra Utara University, Jalan Padang Bulan, Medan, Indonesia

Tonel Barus

Faculty of Mathematics and Natural Sciences, Sumatra Utara University, Jalan Padang Bulan, Medan, Indonesia

Partomuan Simanjuntak3

1Faculty of Mathematics and Natural Sciences, Syiah Kuala University, Jl Tanoh Abee, Kopelma Unsyiah, Banda Aceh, Indonesia 2Faculty of Mathematics and Natural Sciences, Sumatra Utara University, Jalan Padang Bulan, Medan, Indonesia 3Research Centre for Biotechnology, Indonesian Institute of Sciences, Cibinong, Indonesia 4Faculty of Pharmacy, Pancasila University, Srengseng Sawah Jagakarsa, Jakarta, Indonesia *Corresponding author: Tel: +62 81360738524; E-mail: bina_laras@yahoo.com

Corresponding Author(s) : Binawati Ginting

bina_laras@yahoo.com

Asian Journal of Chemistry, Vol. 28 No. 1 (2016): Vol 28 Issue 1
Article Published : October 6, 2015

Abstract

A flavonoid compound i.e. 3,5,7,4'-tetrahydroxy-dihydroflavonol or dihydrocaempferol which has contents an antioxidant activity with IC₅₀ value about 9.75 ppm were successfully isolated and identified. The structures of the obtained compound are identified using spectral data analysis such as ultra-violet, infrared, 1D NMR (¹H NMR, ¹³C NMR), 2D NMR (COSY, HMQC and HMBC) and mass spectra.

Keywords

Nutmeg Myristica fragrans Flavonoid Antioxidant Spectral data analysis

Ginting, B., Marpaung, L., Barus, T., & Simanjuntak3, P. (2015). Isolation and Identification of Flavonoid Compound from Nutmeg Leaves (Myristica fragrans Houtt). Asian Journal of Chemistry, 28(1), 199–202. https://doi.org/10.14233/ajchem.2016.19342

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References

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References

S. Chatterjee, Z. Niaz, S. Gautam, S. Adhikari, P.S. Variyar and A. Sharma, Food Chem., 101, 515 (2007); doi:10.1016/j.foodchem.2006.02.008.

S.P. Piaru, R. Mahmud, A.M.S. Abdul Majid and Z.D. Mahmoud Nassar, Asian Pacific J. Trop. Med., 5, 294 (2012); doi:10.1016/S1995-7645(12)60042-X.

R. Kartika, T. Barus, R. Surbakti and P. Simanjuntak, Asian J. Chem., 26, 6047 (2014); doi:10.14233/ajchem.2014.16562.

G. Yen and H. Chen, J. Agric. Food Chem., 43, 27 (1995); doi:10.1021/jf00049a007.

M.Y. Wang, B.J. West, C.J. Jensen, D. Nowicki, C. Su, A.K. Palu and G. Anderson, Acta Pharmacol. Sin., 23, 1127 (2002).

M. Flach and M.T. Willink, in eds.: D.C. de Guzman and M.S. Siemonsma, Myristica fragrans Houtt. In: Plant Resources of South East Asia, No.: 13, Spices, pp. 143-148 (1999).

J.Y. Chung, J.H. Choo, M.H. Lee and J.K. Hwang, Phytomedicine, 13, 261 (2006); doi:10.1016/j.phymed.2004.04.007.

I.H. Burkill, A Dictionary of the Economic Products of Malay Peninsular, Ministry of Agriculture, Kuala Lumpur, Malaysia, pp. 1547-1556 (1966).

G.S. Sonavane, V.P. Sarveiya, V.S. Kasture and S.B. Kasture, Pharmacol. Biochem. Behav., 71, 239 (2002); doi:10.1016/S0091-3057(01)00660-8.

S.F. Sulaiman and K.L. Ooi, Food Control, 25, 533 (2012); doi:10.1016/j.foodcont.2011.11.005.

M. Hattori, S. Hada, Y. Kawata, Y. Tezuka, T. Kikuchi and T. Namba, Chem. Pharm. Bull. (Tokyo), 35, 3315 (1987); doi:10.1248/cpb.35.3315.

M. Hattori, X.W. Yang, Y.Z. Shu, N. Kakiuchi, Y. Tezuka, T. Kikuchi and T. Namba, Chem. Pharm. Bull. (Tokyo), 36, 648 (1988); doi:10.1248/cpb.36.648.

M. Gopalarkishnan and A.G. Mathews, Indian Cocoa Arecanut Species J., 64, 105 (1983).

A.D. Gupta, V.K. Bansal, V. Babu and N. Maithil, J. Genetic Eng. Biotechnol., 11, 25 (2013); doi:10.1016/j.jgeb.2012.12.001.

S. Pillai, R. Mahmud, W.C. Lee and S. Perumal, APCBEE Procedia, 2, 92 (2012); doi:10.1016/j.apcbee.2012.06.017.

A. Takikawa, K. Abe, M. Yamamoto, S. Ishimaru, M. Yasui, Y. Okubo and K. Yokoigawa, J. Biosci. Bioeng., 94, 315 (2002); doi:10.1016/S1389-1723(02)80170-0.

P. Molyneux, J. Songklanakarin Sci. Technol., 26, 211 (2004).

B. Shan, Y.Z. Cai, M. Sun and H. Corke, J. Agric. Food Chem., 53, 7749 (2005); doi:10.1021/jf051513y.

Issue

Vol. 28 No. 1 (2016): Vol 28 Issue 1

Isolation and Identification of Flavonoid Compound from Nutmeg Leaves (Myristica fragrans Houtt)

Corresponding Author(s) : Binawati Ginting

Abstract

Keywords

Full Article

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References

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