Copyright (c) 2019 AJC
This work is licensed under a Creative Commons Attribution 4.0 International License.
Elemental and Phytochemicals Profile in Ethno Medicinal Plants Used for Treating Cardiovascular Diseases by Mizo-Tribe of North Eastern India
Corresponding Author(s) : K.B. Singh
Asian Journal of Chemistry,
Vol. 31 No. 6 (2019): Vol 31 Issue 6
Abstract
Proton induced X-ray emission (PIXE) and gas chromatography-mass spectroscopy (GC-MS) were used to detect elements as well as phytochemicals in the Centella asiatica and Elsholtzia communis having possible roles for cardio-protections. Elements namely K, Cl, Ca, Fe, Mn, Zn and Cu were present in varying concentration with notable concentration of K, Cl and Fe. Phytochemicals such as stigmasterol, β-sitosterol, phytol and N-hexadeconic acid were detected in the C. asiatica while E. communis was found to contain β-carotene, β-sitosterol, phytol and N-hexadeconic acid. The study reveals that these two ethnomedicinal herbs are found to contain elements and phytochemical known for their cardio-protective roles.
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- S. Govindaraju and P.I. Arulselvi, J. Herbs Spices Med. Plants, 24, 37 (2018); https://doi.org/10.1080/10496475.2017.1369483.
- I. Dib, L. Angenot, A. Mihamou, P.A. Ziyyat and M. Tits, J. Herbal Med., 7, 1 (2017); https://doi.org/10.1016/j.hermed.2016.10.005.
- A. Kolasani, H. Xu and M. Millikan, Food Chem., 127, 1465 (2011); https://doi.org/10.1016/j.foodchem.2011.01.106.
- V. Dushenkov, P.B. Kumar, H. Motto and I. Raskin, Environ. Sci. Technol., 29, 1239 (1995); https://doi.org/10.1021/es00005a015.
- N. Dudareva and E. Pichersky, Plant Physiol., 122, 627 (2000); https://doi.org/10.1104/pp.122.3.627.
- B. Aksel, ed.: A. Bernhoft, A Brief Review of Bioactive Compounds in Plants, In: Bioactive Compounds in Plants-Benefits and Risks for Man and Animals, The Norwegian Academic Science Letters, Oslo, pp. 11-17 (2010).
- R. Govindarajan, M. Vijayakumar and P. Pushpangadan, J. Ethnopharmacol., 99, 165 (2005); https://doi.org/10.1016/j.jep.2005.02.035.
- H. Padalia, R. Poptani and S. Chanda, J. Herbs Spices Med. Plants, 24, 15 (2018); https://doi.org/10.1080/10496475.2017.1357159.
- A. Djeridane, M. Yousfi, B. Nadjemi, D. Boutassouna, P. Stocker and N. Vidal, Food Chem., 97, 654 (2006); https://doi.org/10.1016/j.foodchem.2005.04.028.
- M.Y. Chou, K. Hartvigsen, L.F. Hansen, L. Fogelstrand, P.X. Shaw, A. Boullier, C.J. Binder and J.L. Witztum, J. Intern. Med., 263, 479 (2008); https://doi.org/10.1111/j.1365-2796.2008.01968.x.
- F. Tohru, J. Rodney, U.L. Folz and G.H. David, Cardiovasc. Res., 55, 239 (2002); https://doi.org/10.1016/S0008-6363(02)00328-0.
- J.P. French, K.L. Hamilton, J.C. Quindry, Y. Lee, P.A. Upchurch and S.K. Powers, FASEB J., 22, 2862 (2008); https://doi.org/10.1096/fj.07-102541.
- R. Romero, T. Chaiworapongsa and J. Espinoza, J. Nutr., 133, 1668S (2003); https://doi.org/10.1093/jn/133.5.1668S.
- H. Gylling, J. Plat, S. Turley, H.N. Ginsberg, L. Ellegård, W. Jessup, P.J. Jones, D. Lütjohann, W. Maerz, L. Masana, G. Silbernagel, B. Staels, J. Borén, A.L. Catapano, G. De Backer, J. Deanfield, O.S. Descamps, P.T. Kovanen, G. Riccardi, L. Tokgözoglu and M.J. Chapman, Atheroscl., 232, 346 (2014); https://doi.org/10.1016/j.atherosclerosis.2013.11.043.
- P.K. Rai and H. Lalramnghinglova, J. Med. Plants Res., 4, 1301 (2010).
- B.K. Singh, Y. Ramakrishna and S.V. Ngachan, Genet. Resour. Crop Evol., 61, 1085 (2014); https://doi.org/10.1007/s10722-014-0130-5.
- J.P. Rajan, K.B. Singh, S. Kumar and R.K. Mishra, Asian Pac. J. Trop. Med., 7, S410 (2014); https://doi.org/10.1016/S1995-7645(14)60267-4.
- K.B. Singh and N.M. Singh, J. Adv. Biol., 4, 276 (2014).
- H. Lalramnghinglova, Ethnomedicinal Plants of Mizoram, Bishen Singh Mahendra Pal Singh: New Delhi, edn 1, p. 221(2003).
- N.K.S. Singh, C.B. Devi, T.S. Singh and N.R. Singh, Ind. J. Nat. Prod. Res., 1, 227 (2010).
- S.O. Olabanji, A.C. Adebajo, O.R. Omobuwajo, D. Ceccato, M.C. Buoso and G. Moschini, Nucl. Instrum. Methods Phys. Res. B, 318, 187 (2014); https://doi.org/10.1016/j.nimb.2013.06.052.
- K.B. Ishnava, J.B. Chauhan and M.B. Barad, Saudi J. Biol. Sci., 20, 69 (2013); https://doi.org/10.1016/j.sjbs.2012.11.003.
- L.H. Jia, Y. Liu and Y.Z. Li, J. Pharm. Anal., 1, 213 (2011); https://doi.org/10.1016/j.jpha.2011.04.002.
- J.J. Otten, J. P. Hellwig and L.D. Meyers, Dietary Reference Intake, In: The Essential Guide to Nutrient Requirements, National Academies Press (2006).
- K.O. Soetan, C.O. Olaiya and O.E. Oyewole, Afr. J. Food Sci., 4, 200 (2010).
- L. D’Elia, G. Barba, F.P. Cappuccio and P. Strazzullo, J. Am. Coll. Cardiol., 57, 1210 (2011); https://doi.org/10.1016/j.jacc.2010.09.070.
- J.B. Mason, eds.: L. Goldman, D. Ausiello, Vitamins, Trace Minerals and other Micronutrients, In: Cecil Medicine, Saunders Elsevier: Philadelphia, PA, edn 24 (2011).
- S. Rautiainen, L. Wang, J.E. Manson and H.D. Sesso, Curr. Athero. Rep., 15, 362 (2013); https://doi.org/10.1007/s11883-013-0362-4.
- L.M. Resnick, Am. J. Hypertens., 12, 99 (1999); https://doi.org/10.1016/S0895-7061(98)00275-1.
- S. Puntarulo, Mol. Aspects Med., 26, 299 (2005); https://doi.org/10.1016/j.mam.2005.07.001.
- U.C. Chaturvedi, R. Shrivastava and R.K. Upreti, Curr. Sci., 87, 1536 (2004).
- I. Bureau, C.G. Lewis and M. Fields, Nutr., 14, 366 (1998); https://doi.org/10.1016/S0899-9007(97)00490-5.
- K.L. Olin, R.M. Walter and C.L. Keen, Am. J. Clin. Nutr., 59, 654 (1994); https://doi.org/10.1093/ajcn/59.3.654.
- S.K. Nelson, C.-J. Huang, M.M. Mathias and K.G.D. Allen, J. Nutr., 122, 2101 (1992); https://doi.org/10.1093/jn/122.11.2101.
- D.I. Paynter, Biol. Trace Elem. Res., 2, 121 (1980); https://doi.org/10.1007/BF02798591.
- M. Law, Br. Med. J., 320, 861 (2000); https://doi.org/10.1136/bmj.320.7238.861.
- D.A. Taha, E.K. Wasan, K.M. Wasan and P. Gershkovich, J. Pharm. Pharm. Sci., 18, 344 (2015); https://doi.org/10.18433/J3GC84.
- J.M. McKenney, B.H. Jenks, E. Shneyvas, J.R. Brooks, S.F. Shenoy, C.M. Cook and K.C. Maki, J. Acad. Nutr. Diet., 114, 244 (2014); https://doi.org/10.1016/j.jand.2013.09.023.
- P.J. Jones, M. Raeini-Sarjaz, F.Y. Ntanios, C.A. Vanstone, J.Y. Feng and W.E. Parsons, J. Lipid Res., 41, 697 (2000).
- Z. Tan and F. Shahidi, Eur. J. Lipid Sci. Technol., 116, 1701 (2014); https://doi.org/10.1002/ejlt.201400251.
- V.P. Palace, N. Khaper, Q. Qin and P.K. Singal, Free Radic. Biol. Med., 26, 746 (1999); https://doi.org/10.1016/S0891-5849(98)00266-4.
- G.A. Kurian, S. Philip and T. Varghese, J. Ethanophar., 97, 457 (2005); https://doi.org/10.1016/j.jep.2004.11.028.
References
S. Govindaraju and P.I. Arulselvi, J. Herbs Spices Med. Plants, 24, 37 (2018); https://doi.org/10.1080/10496475.2017.1369483.
I. Dib, L. Angenot, A. Mihamou, P.A. Ziyyat and M. Tits, J. Herbal Med., 7, 1 (2017); https://doi.org/10.1016/j.hermed.2016.10.005.
A. Kolasani, H. Xu and M. Millikan, Food Chem., 127, 1465 (2011); https://doi.org/10.1016/j.foodchem.2011.01.106.
V. Dushenkov, P.B. Kumar, H. Motto and I. Raskin, Environ. Sci. Technol., 29, 1239 (1995); https://doi.org/10.1021/es00005a015.
N. Dudareva and E. Pichersky, Plant Physiol., 122, 627 (2000); https://doi.org/10.1104/pp.122.3.627.
B. Aksel, ed.: A. Bernhoft, A Brief Review of Bioactive Compounds in Plants, In: Bioactive Compounds in Plants-Benefits and Risks for Man and Animals, The Norwegian Academic Science Letters, Oslo, pp. 11-17 (2010).
R. Govindarajan, M. Vijayakumar and P. Pushpangadan, J. Ethnopharmacol., 99, 165 (2005); https://doi.org/10.1016/j.jep.2005.02.035.
H. Padalia, R. Poptani and S. Chanda, J. Herbs Spices Med. Plants, 24, 15 (2018); https://doi.org/10.1080/10496475.2017.1357159.
A. Djeridane, M. Yousfi, B. Nadjemi, D. Boutassouna, P. Stocker and N. Vidal, Food Chem., 97, 654 (2006); https://doi.org/10.1016/j.foodchem.2005.04.028.
M.Y. Chou, K. Hartvigsen, L.F. Hansen, L. Fogelstrand, P.X. Shaw, A. Boullier, C.J. Binder and J.L. Witztum, J. Intern. Med., 263, 479 (2008); https://doi.org/10.1111/j.1365-2796.2008.01968.x.
F. Tohru, J. Rodney, U.L. Folz and G.H. David, Cardiovasc. Res., 55, 239 (2002); https://doi.org/10.1016/S0008-6363(02)00328-0.
J.P. French, K.L. Hamilton, J.C. Quindry, Y. Lee, P.A. Upchurch and S.K. Powers, FASEB J., 22, 2862 (2008); https://doi.org/10.1096/fj.07-102541.
R. Romero, T. Chaiworapongsa and J. Espinoza, J. Nutr., 133, 1668S (2003); https://doi.org/10.1093/jn/133.5.1668S.
H. Gylling, J. Plat, S. Turley, H.N. Ginsberg, L. Ellegård, W. Jessup, P.J. Jones, D. Lütjohann, W. Maerz, L. Masana, G. Silbernagel, B. Staels, J. Borén, A.L. Catapano, G. De Backer, J. Deanfield, O.S. Descamps, P.T. Kovanen, G. Riccardi, L. Tokgözoglu and M.J. Chapman, Atheroscl., 232, 346 (2014); https://doi.org/10.1016/j.atherosclerosis.2013.11.043.
P.K. Rai and H. Lalramnghinglova, J. Med. Plants Res., 4, 1301 (2010).
B.K. Singh, Y. Ramakrishna and S.V. Ngachan, Genet. Resour. Crop Evol., 61, 1085 (2014); https://doi.org/10.1007/s10722-014-0130-5.
J.P. Rajan, K.B. Singh, S. Kumar and R.K. Mishra, Asian Pac. J. Trop. Med., 7, S410 (2014); https://doi.org/10.1016/S1995-7645(14)60267-4.
K.B. Singh and N.M. Singh, J. Adv. Biol., 4, 276 (2014).
H. Lalramnghinglova, Ethnomedicinal Plants of Mizoram, Bishen Singh Mahendra Pal Singh: New Delhi, edn 1, p. 221(2003).
N.K.S. Singh, C.B. Devi, T.S. Singh and N.R. Singh, Ind. J. Nat. Prod. Res., 1, 227 (2010).
S.O. Olabanji, A.C. Adebajo, O.R. Omobuwajo, D. Ceccato, M.C. Buoso and G. Moschini, Nucl. Instrum. Methods Phys. Res. B, 318, 187 (2014); https://doi.org/10.1016/j.nimb.2013.06.052.
K.B. Ishnava, J.B. Chauhan and M.B. Barad, Saudi J. Biol. Sci., 20, 69 (2013); https://doi.org/10.1016/j.sjbs.2012.11.003.
L.H. Jia, Y. Liu and Y.Z. Li, J. Pharm. Anal., 1, 213 (2011); https://doi.org/10.1016/j.jpha.2011.04.002.
J.J. Otten, J. P. Hellwig and L.D. Meyers, Dietary Reference Intake, In: The Essential Guide to Nutrient Requirements, National Academies Press (2006).
K.O. Soetan, C.O. Olaiya and O.E. Oyewole, Afr. J. Food Sci., 4, 200 (2010).
L. D’Elia, G. Barba, F.P. Cappuccio and P. Strazzullo, J. Am. Coll. Cardiol., 57, 1210 (2011); https://doi.org/10.1016/j.jacc.2010.09.070.
J.B. Mason, eds.: L. Goldman, D. Ausiello, Vitamins, Trace Minerals and other Micronutrients, In: Cecil Medicine, Saunders Elsevier: Philadelphia, PA, edn 24 (2011).
S. Rautiainen, L. Wang, J.E. Manson and H.D. Sesso, Curr. Athero. Rep., 15, 362 (2013); https://doi.org/10.1007/s11883-013-0362-4.
L.M. Resnick, Am. J. Hypertens., 12, 99 (1999); https://doi.org/10.1016/S0895-7061(98)00275-1.
S. Puntarulo, Mol. Aspects Med., 26, 299 (2005); https://doi.org/10.1016/j.mam.2005.07.001.
U.C. Chaturvedi, R. Shrivastava and R.K. Upreti, Curr. Sci., 87, 1536 (2004).
I. Bureau, C.G. Lewis and M. Fields, Nutr., 14, 366 (1998); https://doi.org/10.1016/S0899-9007(97)00490-5.
K.L. Olin, R.M. Walter and C.L. Keen, Am. J. Clin. Nutr., 59, 654 (1994); https://doi.org/10.1093/ajcn/59.3.654.
S.K. Nelson, C.-J. Huang, M.M. Mathias and K.G.D. Allen, J. Nutr., 122, 2101 (1992); https://doi.org/10.1093/jn/122.11.2101.
D.I. Paynter, Biol. Trace Elem. Res., 2, 121 (1980); https://doi.org/10.1007/BF02798591.
M. Law, Br. Med. J., 320, 861 (2000); https://doi.org/10.1136/bmj.320.7238.861.
D.A. Taha, E.K. Wasan, K.M. Wasan and P. Gershkovich, J. Pharm. Pharm. Sci., 18, 344 (2015); https://doi.org/10.18433/J3GC84.
J.M. McKenney, B.H. Jenks, E. Shneyvas, J.R. Brooks, S.F. Shenoy, C.M. Cook and K.C. Maki, J. Acad. Nutr. Diet., 114, 244 (2014); https://doi.org/10.1016/j.jand.2013.09.023.
P.J. Jones, M. Raeini-Sarjaz, F.Y. Ntanios, C.A. Vanstone, J.Y. Feng and W.E. Parsons, J. Lipid Res., 41, 697 (2000).
Z. Tan and F. Shahidi, Eur. J. Lipid Sci. Technol., 116, 1701 (2014); https://doi.org/10.1002/ejlt.201400251.
V.P. Palace, N. Khaper, Q. Qin and P.K. Singal, Free Radic. Biol. Med., 26, 746 (1999); https://doi.org/10.1016/S0891-5849(98)00266-4.
G.A. Kurian, S. Philip and T. Varghese, J. Ethanophar., 97, 457 (2005); https://doi.org/10.1016/j.jep.2004.11.028.