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Synthesis of 2-[2-(4-Substituted-1,3,5-triazin-2-loxy)phenyl]-3,3-dimethoxypropanoate
Corresponding Author(s) : Juan Luo
Asian Journal of Chemistry,
Vol. 27 No. 8 (2015): Vol 27 Issue 8
Abstract
In this article, the synthesis of a series of novel compounds, methyl 2-[2-(4-substituted-1,3,5-triazin-2-yloxy)phenyl]-3,3-dimethoxy-propanoate is reported. 4,6-Dichloro-N,N-diethyl-1,3,5-triazin-2-amine reacted with methyl 2-(2-hydroxyphenyl)-3,3-dimethoxypropanoate to give methyl 2-[2-{4-chloro-6- (diethylamino)-1,3,5-triazin-2-yloxy}phenyl]-3,3-dimethoxypropanoate, which then reacted with phenols or thiophenols to give nine novel targets compounds. The structures of target compounds had been characterized by IR, 1H NMR and HRMS.
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- J.C. Yang, Q. Wu, R.L. Liu, S.C. Ma and C.L. Liu, Agrochemicals, 47, 402 (2008).
- G.S. Zhang, Pesticides Sci. Admin., 24, 30 (2003).
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- G.H. Lu, H.B. Chu, M. Chen and C.L. Yang, Chin. Chem. Lett., 25, 61 (2014); doi:10.1016/j.cclet.2013.10.007.
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- M. Li, R.l. Liu, Z.N. Li, C.L. Liu and Z.M. Li, Agrochemicals, 48, 405 (2009).
- K. Sun, H.F. Wu, H. Zhang, F.R. Wang, W. Cao, J. Zhao, H. Yang and J.B. Xu, Modern Agrochem., 12, 17 (2013).
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References
J.C. Yang, Q. Wu, R.L. Liu, S.C. Ma and C.L. Liu, Agrochemicals, 47, 402 (2008).
G.S. Zhang, Pesticides Sci. Admin., 24, 30 (2003).
S. Kroiß and W. Steglich, Tetrahedron, 60, 4921 (2004); doi:10.1016/j.tet.2004.03.092.
D.G. Brooke and J.C. Morris, Tetrahedron Lett., 49, 2414 (2008); doi:10.1016/j.tetlet.2008.02.056.
B. Chai, S.Y. Wang, W.Q. Yu, H.C. Li, C.J. Song, Y. Xu, C.L. Liu and J.B. Chang, Bioorg. Med. Chem. Lett., 23, 3505 (2013); doi:10.1016/j.bmcl.2013.04.045.
G.H. Lu, H.B. Chu, M. Chen and C.L. Yang, Chin. Chem. Lett., 25, 61 (2014); doi:10.1016/j.cclet.2013.10.007.
H.C. Li, B.S. Chai, Z.N. Li, J.C. Yang and C.L. Liu, Chin. Chem. Lett., 20, 1287 (2009); doi:10.1016/j.cclet.2009.05.028.
B.S. Chai, C.L. Liu, H.C. Li, S.W. Liu, Y. Xu, Y.Q. Song and J.B. Chang, Chin. Chem. Lett., 25, 137 (2014); doi:10.1016/j.cclet.2013.10.006.
M. Li, R.l. Liu, Z.N. Li, C.L. Liu and Z.M. Li, Agrochemicals, 48, 405 (2009).
K. Sun, H.F. Wu, H. Zhang, F.R. Wang, W. Cao, J. Zhao, H. Yang and J.B. Xu, Modern Agrochem., 12, 17 (2013).
H.Y. Wang, S.Q. Li, Z.J. Fan, J.Y. Chen, F. Chai, S. Li and C.L. Liu, Fine Chem. Intermed., 40, 66 (2010).
A.Y. Guan, C.L. Liu, Z.N. Li and M.X. Zhang, Chin. Chem. Lett., 22, 663 (2011); doi:10.1016/j.cclet.2010.12.028.
T. Hermon and E.Y. Tshuva, J. Org. Chem., 73, 5953 (2008); doi:10.1021/jo800966s.
J. Dong, D.H. Liao, J.S. Lou and H.J. Pi, Fine Chem. Intermed., 37, 25 (2007).