Synthesis of Novel 2,4-Di(o-Hydroxyphenyl)-6-substituted Amino-1,3,5-triazine

Junrong Jiang

doi:10.14233/ajchem.2015.18434

Issue

Vol. 27 No. 5 (2015): Vol 27 Issue 5

Issue Published : February 20, 2015

This work is licensed under a Creative Commons Attribution 4.0 International License.

Synthesis of Novel 2,4-Di(o-Hydroxyphenyl)-6-substituted Amino-1,3,5-triazine

https://doi.org/10.14233/ajchem.2015.18434

Junrong Jiang

State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou 310014, P.R. China; Biopharmaceutical R & D Center, Taizhou Vocational and Technical College, Taizhou 318000, P.R. China

Corresponding Author(s) : Junrong Jiang

jiangjr@tzvtc.com

Asian Journal of Chemistry, Vol. 27 No. 5 (2015): Vol 27 Issue 5
Article Published : February 20, 2015

Abstract

Seven novel 1,3,5-triazine derivatives were synthesized in good to high yields (69.19-91.15 %) by the reaction of substituted guanidine with 2-(2-hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one in ethanol. The products were recrystallized from ethanol or ethanol-DMF mixture and their structures were confirmed by ¹H NMR and FT-IR.

Keywords

Guanidine 2-(2-Hydroxyphenyl)-4H-benzo[e][1 3]oxazin-4-one Triazine

Jiang, J. (2015). Synthesis of Novel 2,4-Di(o-Hydroxyphenyl)-6-substituted Amino-1,3,5-triazine. Asian Journal of Chemistry, 27(5), 1959–1960. https://doi.org/10.14233/ajchem.2015.18434

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References

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G.H. Kuo, A. Deangelis, S. Emanuel, A. Wang, Y. Zhang, P.J. Connolly, X. Chen, R.H. Gruninger, C. Rugg, A.F. Pesquera, S.A. Middleton, L. Jolliffe and W.V. Murray, J. Med. Chem., 48, 4535 (2005); doi:10.1021/jm040214h.

Y.F. Zhou, Z.X. Sun, J.M. Froelich, T. Hermann and D. Wall, Bioorg. Med. Chem. Lett., 16, 5451 (2006); doi:10.1016/j.bmcl.2006.07.052.

E. Piera, F. Comelles, P. Erra and M.R. Infante, J. Chem. Soc., Perkin Trans. II, 335 (1998); doi:10.1039/A705565J.

D. Schaubroeck, J. De Baets, T. Desmet, P. Dubruel, E. Schacht, L. Van Vaeck and A. Van Calster, Appl. Surf. Sci., 256, 6269 (2010); doi:10.1016/j.apsusc.2010.04.003.

X.C. Wang, G. Wang and X.C. Jiao, Agrochemical, 50, 320 (2011).

Y.F. Sun, D.F. Zhao and H.S. Freeman, Dyes Pigments, 74, 608 (2007); doi:10.1016/j.dyepig.2006.04.001.

Y.G. Huang, Y.Q. Zhang and J.M. Shreeve, Chem. Eur. J., 17, 1538 (2011); doi:10.1002/chem.201002363.

J.A. Mikroyannidis, S.S. Sharma, Y.K. Vijay and G.D. Sharma, ACS Appl. Mater. Interfaces, 2, 270 (2010); doi:10.1021/am9006897.

A. García, B. Insuasty, M.Á. Herranz, R. Martínez-Álvarez and N. Martín, Org. Lett., 11, 5398 (2009); doi:10.1021/ol902203t.

A.R. Silva, V. Budarin, J.H. Clark, C. Freire and B. de Castro, Carbon, 45, 1951 (2007); doi:10.1016/j.carbon.2007.06.013.

G. Blotny, Tetrahedron, 62, 9507 (2006); doi:10.1016/j.tet.2006.07.039.

T. Bolle, A. Valet, D.G. Leppard, S.M. Andrews, R. Ravichandran, M. Grob and D. Simon, US Patent 2005075465 (2005).

J. Haase, T. Ehlis, E. Borsos, D. Huglin and B. Herzog, US Patent 2005129632 (2005).

D. Reinehr, G. Metzger, P. Michaelis and H. Luther, US Patent 2007274933 (2007).

K.D.Burdeska, EP 0497734(1992).

D. Reinehr and J.P. Bacher, US Patent 5478935(1995).

R.B. Gupta, D.J. Jakiela, S. Venimadhavan, R.C. Cappadona and V.K. Pai, US Patent 2004204585 (2004).

R.B. Gupta, D.J. Jakiela, S. Venimadhvan, R.C. Cappadona and V.K. Pai, US Patent 6486317(2002).

C.A. Migdal, J.B. Hines and E.W. Kluger, US Patent 4826978(1989).

H. Henneberger and M. Wagner, US Patent 543813(1995).

M. Sun, H.T. Wei, C.L. Shi, Y.G. Zheng and M. Ji, Chin. J. New Drugs, 18, 850 (2009).

Issue

Vol. 27 No. 5 (2015): Vol 27 Issue 5

Synthesis of Novel 2,4-Di(o-Hydroxyphenyl)-6-substituted Amino-1,3,5-triazine

Corresponding Author(s) : Junrong Jiang

Abstract

Keywords

Full Article

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