Nine Representative Phytochemicals Occurring in Leaves and Rhizomes of Alpinia oxyphylla Different to Those of Fruits Determined Using LC-MS/MS

Yong-Hui Li; Feng Chen; Hai-Long Li; Yin-Feng Tan; Jun-Qing Zhang

doi:10.14233/ajchem.2015.18017

Issue

Vol. 27 No. 5 (2015): Vol 27 Issue 5

Issue Published : February 20, 2015

This work is licensed under a Creative Commons Attribution 4.0 International License.

Nine Representative Phytochemicals Occurring in Leaves and Rhizomes of Alpinia oxyphylla Different to Those of Fruits Determined Using LC-MS/MS

https://doi.org/10.14233/ajchem.2015.18017

Yong-Hui Li

School of Pharmacy, Hainan Medical University, Haikou, P.R. China; Hainan Provincial Key Laboratory of R&D of Tropical Herbs, Haikou, P.R. China

Feng Chen

School of Pharmacy, Hainan Medical University, Haikou, P.R. China; Hainan Provincial Key Laboratory of R&D of Tropical Herbs, Haikou, P.R. China

Hai-Long Li

School of Pharmacy, Hainan Medical University, Haikou, P.R. China; Hainan Provincial Key Laboratory of R&D of Tropical Herbs, Haikou, P.R. China

Yin-Feng Tan

School of Pharmacy, Hainan Medical University, Haikou, P.R. China; Hainan Provincial Key Laboratory of R&D of Tropical Herbs, Haikou, P.R. China

Jun-Qing Zhang

School of Pharmacy, Hainan Medical University, Haikou, P.R. China; Hainan Provincial Key Laboratory of R&D of Tropical Herbs, Haikou, P.R. China

Corresponding Author(s) : Jun-Qing Zhang

jqzhang2011@163.com

Asian Journal of Chemistry, Vol. 27 No. 5 (2015): Vol 27 Issue 5
Article Published : February 20, 2015

Abstract

Alpinia oxyphylla is commonly used in traditional East Asian medicine. Usually, only its fruits are regarded as an important medicinal plant part. However, the plant resource of A. oxyphylla is insufficient. Therefore, we question whether the leaves or rhizomes can be used as alternative parts for this genus based on phytochemical composition. In the present study, nine chemical components (i.e., tectochrysin, izalpinin, chrysin, apigenin-4',7-dimethyl ether, kaempferide, yakuchinone A, yakuchinone B, oxyphyllacinol and nootkatone) were regarded as representative constitutes of fruits. The abundance of the nine constituents in leaves and rhizomes was evaluated by a validated LC-MS/MS method and then compared with that of fruits. The results revealed that the monitoring of the nine phytochemicals were also made in leaves or rhizomes samples as fruits. The content levels of these compounds were comparable between leaves and rhizomes, but both were significantly less than fruits. As the fruits ripening (from day 10 to day 50), the content levels of flavonoid were increased with fluctuation in rhizomes. In contrast, the concentrations measured in leaves decreased. The content changes of nootkatone and diarylheptanoid with growth time were similar between rhizomes and leaves. Additional work is required to assess the bioactive properties of the fruits, leaves or rhizomes and make the best use of these valuable medicinal plant resources.

Keywords

A. oxyphylla rhizomes and leaves Harvest times Diarylheptanoids Flavonoids LC-MS/MS

Li, Y.-H., Chen, F., Li, H.-L., Tan, Y.-F., & Zhang, J.-Q. (2015). Nine Representative Phytochemicals Occurring in Leaves and Rhizomes of Alpinia oxyphylla Different to Those of Fruits Determined Using LC-MS/MS. Asian Journal of Chemistry, 27(5), 1837–1842. https://doi.org/10.14233/ajchem.2015.18017

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References

P.P.H. But, T. Kimura, J.X. Guo and C.K. Sung, International Collation of Traditional and Folk Medicine: Northeast Asia, Part II, Alpinia oxyphylla, World Scientific, Singapore, p. 202 (1997).
K.-S. Chun, J.-Y. Kang, O.H. Kim, H. Kang and Y.-J. Surh, J. Environ. Pathol. Toxicol. Oncol., 21, 9 (2002); doi:10.1615/JEnvironPatholToxicolOncol.v21.i2.60.
T.Y. Shin, J.H. Won, H.M. Kim and S.H. Kim, Am. J. Chin. Med., 29, 293 (2001); doi:10.1142/S0192415X01000319.
J. Yamahara, Y.H. Li and Y. Tamai, Chem. Pharm. Bull. (Tokyo), 38, 3053 (1990); doi:10.1248/cpb.38.3053.
X.Y. Yu, L.J. An, Y.Q. Wang, H. Zhao and C.Z. Gao, Toxicol. Lett., 144, 205 (2003); doi:10.1016/S0378-4274(03)00219-4.
Z.J. Zhang, L.C. Cheang, M.W. Wang, G.H. Li, I.K. Chu, Z.X. Lin and S.M. Lee, Cell. Mol. Neurobiol., 32, 27 (2012); doi:10.1007/s10571-011-9731-0.
L. Huang, Y. Zhu, Z. Dong, G.B. Chen, J. Li and J. Zhao, Zhong Yao Cai, 31, 722 (2008).
F. Chen, H.L. Li, Y.H.Y.F. Li, Y.-F. Tan and J.-Q. Zhang, Chem. Cent. J., 7, 131 (2013); doi:10.1186/1752-153X-7-131.
http://www.39kf.com/medicine/news/ysfx/2012-09-29-838438.shtml.
W.J. Song, Y.H. Li, J.G. Wang, Z.Y. Li and J.Q. Zhang, Drug Test. Anal., 6, 239 (2014); doi:10.1002/dta.1462.
Z.J. Qing, W. Yong, L.Y. Hui, L.W. Yong, L.H. Long, D.J. Ao and P.L. Xia, Arch. Pharm. Res., 35, 2143 (2012); doi:10.1007/s12272-012-1211-7.
Y.H. Li, F. Chen, J.F. Wang, Y. Wang, J.Q. Zhang and T. Guo, Chem. Cent. J., 7, 134 (2013); doi:10.1186/1752-153X-7-134.
F. Chen, H.L. Li, Y.F. Tan, W.W. Guan, J.Q. Zhang, Y.H. Li, Y.S. Zhao and Z.M. Qin, Molecules, 19, 4510 (2014); doi:10.3390/molecules19044510.
E.J. Seo, D.U. Lee, J.H. Kwak, S.M. Lee, Y.S. Kim and Y.S. Jung, J. Ethnopharmacol., 135, 48 (2011); doi:10.1016/j.jep.2011.02.025.
K. Tsoyi, H.J. Jang, Y.S. Lee, Y. Kim, H.J. Kim, H.G. Seo, J.H. Lee, J.H. Kwak, D.U. Lee and K.C. Chang, J. Ethnopharmacol., 137, 1311 (2011); doi:10.1016/j.jep.2011.07.062.
R.J. Lin, C.M. Yen, T.H. Chou, F.Y. Chiang, G.H. Wang, Y.P. Tseng, L. Wang, T.W. Huang, H.C. Wang, L.P. Chan, H.Y. Ding and C.H. Liang, BMC Complement. Altern. Med., 13, 237 (2013); doi:10.1186/1472-6882-13-237.
R. Yamazaki, H. Hatano, R. Aiyama, T. Matsuzaki, S. Hashimoto and T. Yokokura, Eur. J. Pharmacol., 404, 375 (2000); doi:10.1016/S0014-2999(00)00620-8.
K.S. Chun, K.K. Park, J. Lee, M. Kang and Y.J. Surh, Oncol. Res., 13, 37 (2002).
K.S. Chun, Y. Sohn, H.S. Kim, O.H. Kim, K.K. Park, J.M. Lee, A. Moon and S.S. Lee, Mutat. Res., 428, 49 (1999); doi:10.1016/S1383-5742(99)00031-9.
J.Q. Zhang, S. Wang, Y.H. Li, P. Xu, F. Chen, Y. Tan and J.A. Duan, Fitoterapia, 89, 149 (2013); doi:10.1016/j.fitote.2013.04.001.

References

P.P.H. But, T. Kimura, J.X. Guo and C.K. Sung, International Collation of Traditional and Folk Medicine: Northeast Asia, Part II, Alpinia oxyphylla, World Scientific, Singapore, p. 202 (1997).

K.-S. Chun, J.-Y. Kang, O.H. Kim, H. Kang and Y.-J. Surh, J. Environ. Pathol. Toxicol. Oncol., 21, 9 (2002); doi:10.1615/JEnvironPatholToxicolOncol.v21.i2.60.

T.Y. Shin, J.H. Won, H.M. Kim and S.H. Kim, Am. J. Chin. Med., 29, 293 (2001); doi:10.1142/S0192415X01000319.

J. Yamahara, Y.H. Li and Y. Tamai, Chem. Pharm. Bull. (Tokyo), 38, 3053 (1990); doi:10.1248/cpb.38.3053.

X.Y. Yu, L.J. An, Y.Q. Wang, H. Zhao and C.Z. Gao, Toxicol. Lett., 144, 205 (2003); doi:10.1016/S0378-4274(03)00219-4.

Z.J. Zhang, L.C. Cheang, M.W. Wang, G.H. Li, I.K. Chu, Z.X. Lin and S.M. Lee, Cell. Mol. Neurobiol., 32, 27 (2012); doi:10.1007/s10571-011-9731-0.

L. Huang, Y. Zhu, Z. Dong, G.B. Chen, J. Li and J. Zhao, Zhong Yao Cai, 31, 722 (2008).

F. Chen, H.L. Li, Y.H.Y.F. Li, Y.-F. Tan and J.-Q. Zhang, Chem. Cent. J., 7, 131 (2013); doi:10.1186/1752-153X-7-131.

http://www.39kf.com/medicine/news/ysfx/2012-09-29-838438.shtml.

W.J. Song, Y.H. Li, J.G. Wang, Z.Y. Li and J.Q. Zhang, Drug Test. Anal., 6, 239 (2014); doi:10.1002/dta.1462.

Z.J. Qing, W. Yong, L.Y. Hui, L.W. Yong, L.H. Long, D.J. Ao and P.L. Xia, Arch. Pharm. Res., 35, 2143 (2012); doi:10.1007/s12272-012-1211-7.

Y.H. Li, F. Chen, J.F. Wang, Y. Wang, J.Q. Zhang and T. Guo, Chem. Cent. J., 7, 134 (2013); doi:10.1186/1752-153X-7-134.

F. Chen, H.L. Li, Y.F. Tan, W.W. Guan, J.Q. Zhang, Y.H. Li, Y.S. Zhao and Z.M. Qin, Molecules, 19, 4510 (2014); doi:10.3390/molecules19044510.

E.J. Seo, D.U. Lee, J.H. Kwak, S.M. Lee, Y.S. Kim and Y.S. Jung, J. Ethnopharmacol., 135, 48 (2011); doi:10.1016/j.jep.2011.02.025.

K. Tsoyi, H.J. Jang, Y.S. Lee, Y. Kim, H.J. Kim, H.G. Seo, J.H. Lee, J.H. Kwak, D.U. Lee and K.C. Chang, J. Ethnopharmacol., 137, 1311 (2011); doi:10.1016/j.jep.2011.07.062.

R.J. Lin, C.M. Yen, T.H. Chou, F.Y. Chiang, G.H. Wang, Y.P. Tseng, L. Wang, T.W. Huang, H.C. Wang, L.P. Chan, H.Y. Ding and C.H. Liang, BMC Complement. Altern. Med., 13, 237 (2013); doi:10.1186/1472-6882-13-237.

R. Yamazaki, H. Hatano, R. Aiyama, T. Matsuzaki, S. Hashimoto and T. Yokokura, Eur. J. Pharmacol., 404, 375 (2000); doi:10.1016/S0014-2999(00)00620-8.

K.S. Chun, K.K. Park, J. Lee, M. Kang and Y.J. Surh, Oncol. Res., 13, 37 (2002).

K.S. Chun, Y. Sohn, H.S. Kim, O.H. Kim, K.K. Park, J.M. Lee, A. Moon and S.S. Lee, Mutat. Res., 428, 49 (1999); doi:10.1016/S1383-5742(99)00031-9.

J.Q. Zhang, S. Wang, Y.H. Li, P. Xu, F. Chen, Y. Tan and J.A. Duan, Fitoterapia, 89, 149 (2013); doi:10.1016/j.fitote.2013.04.001.

Issue

Vol. 27 No. 5 (2015): Vol 27 Issue 5

Nine Representative Phytochemicals Occurring in Leaves and Rhizomes of Alpinia oxyphylla Different to Those of Fruits Determined Using LC-MS/MS

Corresponding Author(s) : Jun-Qing Zhang

Abstract

Keywords

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